RT Journal Article SR Electronic T1 Application of the Lugano Classification for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The PRoLoG Consensus Initiative (Part 2—Technical) JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 239 OP 243 DO 10.2967/jnumed.122.264124 VO 64 IS 2 A1 Ricard, Fabien A1 Barrington, Sally A1 Korn, Ron A1 Brueggenwerth, Guenther A1 Trotman, Judith A1 Cheson, Bruce A1 Salles, Gilles A1 Schwartz, Larry A1 Goldmacher, Greg A1 Jarecha, Rudresh A1 Narang, Jayant A1 Broussais, Florence A1 Galette, Paul A1 Liu, Min A1 Bajpai, Surabhi A1 Perlman, Eric A1 Gillis, Julie A1 Smalberg, Ira A1 Terve, Pierre A1 Zahlmann, Gudrun A1 Schmid, Annette YR 2023 UL http://jnm.snmjournals.org/content/64/2/239.abstract AB The aim of this initiative was to provide consensus recommendations from a consortium of academic and industry experts in the field of lymphoma and imaging for the consistent application of imaging assessment with the Lugano classification. Methods: Consensus was obtained through a series of meetings from July 2019 to October 2021 sponsored by the PINTaD (Pharma Imaging Network for Therapeutics and Diagnostics) as part of the ProLoG (PINTaD RespOnse criteria in Lymphoma wOrking Group) consensus initiative. Results: Consensus recommendations encompass all technical imaging aspects of the Lugano classification. Some technical considerations for PET/CT and diagnostic CT are clarified with regards to required imaging series and scan visits, as well as acquisition and reconstruction of PET images and influence of lesion size and background activity. Recommendations are given on the role of imaging and clinical reviewers as well as on training and monitoring. Finally, an example template of an imaging case report form is provided to support efficient collection of data with Lugano Classification. Conclusion: Consensus recommendations are made to comprehensively address technical and imaging areas of inconsistency and ambiguity in the classification encountered by end users. Such guidance should be used to support standardized acquisition and evaluation with the Lugano 2014.