PT - JOURNAL ARTICLE AU - Saboury, Babak AU - Bradshaw, Tyler AU - Boellaard, Ronald AU - Buvat, Irène AU - Dutta, Joyita AU - Hatt, Mathieu AU - Jha, Abhinav K. AU - Li, Quanzheng AU - Liu, Chi AU - McMeekin, Helena AU - Morris, Michael A. AU - Pandit-Taskar, Neeta AU - Scott, Peter J.H. AU - Siegel, Eliot AU - Sunderland, John J. AU - Pandit-Taskar, Neeta AU - Wahl, Richard L. AU - Zuehlsdorff, Sven AU - Rahmim, Arman TI - Artificial Intelligence in Nuclear Medicine: Opportunities, Challenges, and Responsibilities Toward a Trustworthy Ecosystem AID - 10.2967/jnumed.121.263703 DP - 2022 Dec 01 TA - Journal of Nuclear Medicine PG - jnumed.121.263703 4099 - http://jnm.snmjournals.org/content/early/2022/12/15/jnumed.121.263703.short 4100 - http://jnm.snmjournals.org/content/early/2022/12/15/jnumed.121.263703.full AB - Trustworthiness is a core tenet of medicine. The patient-physician relationship is evolving from a dyad to a broader ecosystem of healthcare. With the emergence of artificial intelligence (AI) in medicine, the elements of trust must be revisited. We envision a roadmap for the establishment of trustworthy AI ecosystems in nuclear medicine. In this report, AI is contextualized in the history of technological revolutions. Opportunities for AI applications in nuclear medicine related to diagnosis, therapy and workflow efficiency, as well as emerging challenges and critical responsibilities are discussed. Establishing and maintaining leadership in AI requires a concerted effort to promote the rational and safe deployment of this innovative technology by engaging patients, nuclear medicine physicians, scientists, technologists, referring providers, among other stakeholders, while protecting our patients and society. This strategic plan is prepared by the AI Task Force of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).