RT Journal Article
SR Electronic
T1 Joint EANM, SNMMI, and IAEA Enabling Guide: How to Set up a Theranostics Center
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1836
OP 1843
DO 10.2967/jnumed.122.264321
VO 63
IS 12
A1 Herrmann, Ken
A1 Giovanella, Luca
A1 Santos, Andrea
A1 Gear, Jonathan
A1 Ozgen Kiratli, Pinar
A1 Kurth, Jens
A1 Denis-Bacelar, Ana M.
A1 Hustinx, Roland
A1 Patt, Marianne
A1 Wahl, Richard L.
A1 Paez, Diana
A1 Giammarile, Francesco
A1 Jadvar, Hossein
A1 Pandit-Taskar, Neeta
A1 Ghesani, Munir
A1 Kunikowska, Jolanta
YR 2022
UL http://jnm.snmjournals.org/content/63/12/1836.abstract
AB The theranostics concept using the same target for both imaging and therapy dates back to the middle of the last century, when radioactive iodine was first used to treat thyroid diseases. Since then, radioiodine has become broadly established clinically for diagnostic imaging and therapy of benign and malignant thyroid disease, worldwide. However, only since the approval of SSTR2-targeting theranostics following the NETTER-1 trial in neuroendocrine tumors, and the positive outcome of the VISION trial has theranostics gained substantial attention beyond nuclear medicine. The roll-out of radioligand therapy for treating a high-incidence tumor such as prostate cancer requires the expansion of existing and the establishment of new theranostics centers. Despite wide global variation in the regulatory, financial and medical landscapes, this guide attempts to provide valuable information to enable interested stakeholders to safely initiate and operate theranostic centers. This enabling guide does not intend to answer all possible questions, but rather to serve as an overarching framework for multiple, more detailed future initiatives. It recognizes that there are regional differences in the specifics of regulation of radiation safety, but common elements of best practice valid globally.