RT Journal Article SR Electronic T1 Hot Spot Imaging in Cardiovascular Diseases: An Information Statement from SNMMI, ASNC, and EANM JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1722 OP 1740 DO 10.2967/jnumed.122.264311 VO 63 IS 11 A1 Sperry, Brett W. A1 Bateman, Timothy M. A1 Akin, Esma A. A1 Bravo, Paco E. A1 Chen, Wengen A1 Dilsizian, Vasken A1 Hyafil, Fabien A1 Khor, Yiu Ming A1 Miller, Robert J.H. A1 Slart, Riemer H.J.A. A1 Slomka, Piotr A1 Verberne, Hein A1 Miller, Edward J. A1 Liu, Chi YR 2022 UL http://jnm.snmjournals.org/content/63/11/1722.abstract AB This information statement from the Society of Nuclear Medicine and Molecular Imaging, American Society of Nuclear Cardiology, and European Association of Nuclear Medicine describes the performance, interpretation, and reporting of hot spot imaging in nuclear cardiology. The field of nuclear cardiology has historically focused on cold spot imaging for the interpretation of myocardial ischemia and infarction. Hot spot imaging has been an important part of nuclear medicine, particularly for oncology or infection indications, and the use of hot spot imaging in nuclear cardiology continues to expand. This document focuses on image acquisition and processing, methods of quantification, indications, protocols, and reporting of hot spot imaging. Indications discussed include myocardial viability, myocardial inflammation, device or valve infection, large vessel vasculitis, valve calcification and vulnerable plaques, and cardiac amyloidosis. This document contextualizes the foundations of image quantification and highlights reporting in each indication for the cardiac nuclear imager.