PT  - JOURNAL ARTICLE
AU  - Gonzalez-Montoro, Andrea
AU  - Ullah, Muhammad Nasir
AU  - Levin, Craig S.
TI  - Advances in Detector Instrumentation for PET
AID  - 10.2967/jnumed.121.262509
DP  - 2022 Aug 01
TA  - Journal of Nuclear Medicine
PG  - 1138--1144
VI  - 63
IP  - 8
4099  - http://jnm.snmjournals.org/content/63/8/1138.short
4100  - http://jnm.snmjournals.org/content/63/8/1138.full
SO  - J Nucl Med2022 Aug 01; 63
AB  - During the last 3 decades, PET has become a standard-of-care imaging technique used in the management of cancer and in the characterization of neurologic disorders and cardiovascular disease. It has also emerged as a prominent molecular imaging method to study the basic biologic pathways of disease in rodent models. This review describes the basics of PET detectors, including a detailed description of indirect and direct 511-keV photon detection methods. We will also cover key detector performance parameters and describe detector instrumentation advances during the last decade.