%0 Journal Article %A Harleen Kaur %A Isis Gayed %A Fathima Fijula Palot Manzil %T False positive radioactive iodine uptake in Nabothian cyst in a patient with thyroid cancer. %D 2022 %J Journal of Nuclear Medicine %P 2713-2713 %V 63 %N supplement 2 %X 2713 Introduction: Radioactive iodine (I-131) is widely used for remnant ablation of the well differentiated thyroid cancer. Post ablation imaging plays a vital role in determining the disease in the neck as well as evaluate the distant sites of metastasis.We present a case of false positive radiotracer uptake in the Nabothian cyst on a post ablation whole body and SPECT/CT I-131 scan in a patient with thyroid cancer.Methods: Review of electronic medical record and institutional PACS.Results: A 44-year-old female presented to our hospital with slowly growing neck mass. Initial work up with CT and Ultrasound showed large substernal goiter on the left side. Fine need biopsy was suspicious for malignancy. Patient underwent total thyroidectomy and surgical pathology revealed 7 cm papillary thyroid carcinoma. Subsequently patient was treated with 100 mci of I-131 and post ablation scan was obtained in 10 days. Whole body I- 131 scan showed uptake in the neck consistent with residual thyroid tissue. Physiological uptake was also seen in the salivary glands and bowel. Additionally, there was intense focal radiotracer uptake in the pelvis with another adjacent small subtle focus. It was not clear if this was activity in the bladder or there was additional unknown lesion in the pelvis. SPECT/CT images of the pelvis were obtained which localized the larger focus within the cervix and smaller focus within the vagina. The findings were most consistent with Nabothian cyst uptake in the cervix and possible inflammation in the vagina. Ultrasound evaluation was recommended to further characterize and confirm these findings. US was negative for any suspicious pelvic masses but showed Nabothian cysts in the cervix.Conclusions: This is an interesting case with false positive radioactive iodine uptake in Nabothian cysts in the cervix. Our case also highlights the value of SPECT/CT in localizing these lesions which otherwise are difficult to evaluate by planar imaging. %U