RT Journal Article
SR Electronic
T1 A Guideline for Clinicians Performing Clinical Studies with Fluorescence Imaging
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 640
OP 645
DO 10.2967/jnumed.121.262975
VO 63
IS 5
A1 Heeman, Wido
A1 Vonk, Jasper
A1 Ntziachristos, Vasilis
A1 Pogue, Brian W.
A1 Dierckx, Rudi A.J.O.
A1 Kruijff, Schelto
A1 van Dam, Gooitzen M.
YR 2022
UL http://jnm.snmjournals.org/content/63/5/640.abstract
AB Fluorescence imaging is an emerging imaging technique that has shown many benefits for clinical care. Currently, the field is in rapid clinical translation, and an unprecedented number of clinical trials are performed. Clinicians are inundated with numerous opportunities and combinations of different imaging modalities. To streamline this process, a multidisciplinary approach is needed with drug discovery, software and systems engineering, and translational medicine. Here, we discuss the main constituents of a uniform fluorescence imaging protocol to match the clinical need and ensure consistent study designs and reliable data collection in clinical trials. In an era in which the potential of fluorescence imaging has become evident, consistent conduct of studies, data analysis, and data interpretation is essential for implementation into the standard of care.