TY - JOUR T1 - A Guideline for Clinicians Performing Clinical Studies with Fluorescence Imaging JF - Journal of Nuclear Medicine JO - J Nucl Med SP - 640 LP - 645 DO - 10.2967/jnumed.121.262975 VL - 63 IS - 5 AU - Wido Heeman AU - Jasper Vonk AU - Vasilis Ntziachristos AU - Brian W. Pogue AU - Rudi A.J.O. Dierckx AU - Schelto Kruijff AU - Gooitzen M. van Dam Y1 - 2022/05/01 UR - http://jnm.snmjournals.org/content/63/5/640.abstract N2 - Fluorescence imaging is an emerging imaging technique that has shown many benefits for clinical care. Currently, the field is in rapid clinical translation, and an unprecedented number of clinical trials are performed. Clinicians are inundated with numerous opportunities and combinations of different imaging modalities. To streamline this process, a multidisciplinary approach is needed with drug discovery, software and systems engineering, and translational medicine. Here, we discuss the main constituents of a uniform fluorescence imaging protocol to match the clinical need and ensure consistent study designs and reliable data collection in clinical trials. In an era in which the potential of fluorescence imaging has become evident, consistent conduct of studies, data analysis, and data interpretation is essential for implementation into the standard of care. ER -