RT Journal Article SR Electronic T1 Nuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP jnumed.121.262567 DO 10.2967/jnumed.121.262567 A1 Tyler J. Bradshaw A1 Ronald Boellaard A1 Joyita Dutta A1 Abhinav K. Jha A1 Paul Jacobs A1 Quanzheng Li A1 Chi Liu A1 Arkadiusz Sitek A1 Babak Saboury A1 Peter J.H. Scott A1 Piotr J. Slomka A1 John J. Sunderland A1 Richard L. Wahl A1 Fereshteh Yousefirizi A1 Sven Zuehlsdorff A1 Arman Rahmim A1 Irène Buvat YR 2021 UL http://jnm.snmjournals.org/content/early/2021/11/04/jnumed.121.262567.abstract AB The nuclear medicine field has seen a rapid expansion of academic and commercial interests in developing artificial intelligence (AI) algorithms. Users and developers can avoid some of the pitfalls of AI by recognizing and following best practices in AI algorithm development. In this article, recommendations for technical best practices for developing AI algorithms in nuclear medicine are provided, beginning with general recommendations followed by descriptions on how one might practice these principles for specific topics within nuclear medicine. This report was produced by the AI Task Force of the Society of Nuclear Medicine and Molecular Imaging.