PT - JOURNAL ARTICLE AU - Radchenko, Valery AU - Morgenstern, Alfred AU - Jalilian, Amir R. AU - Ramogida, Caterina F. AU - Cutler, Cathy AU - Duchemin, Charlotte AU - Hoehr, Cornelia AU - Haddad, Ferrid AU - Bruchertseifer, Frank AU - Gausemel, Haavar AU - Yang, Hua AU - Osso, Joao Alberto AU - Washiyama, Kohshin AU - Czerwinski, Kenneth AU - Leufgen, Kirsten AU - Pruszyński, Marek AU - Valzdorf, Olga AU - Causey, Patrick AU - Schaffer, Paul AU - Perron, Randy AU - Maxim, Samsonov AU - Wilbur, D. Scott AU - Stora, Thierry AU - Li, Yawen TI - Production and Supply of α-Particle–Emitting Radionuclides for Targeted α-Therapy AID - 10.2967/jnumed.120.261016 DP - 2021 Nov 01 TA - Journal of Nuclear Medicine PG - 1495--1503 VI - 62 IP - 11 4099 - http://jnm.snmjournals.org/content/62/11/1495.short 4100 - http://jnm.snmjournals.org/content/62/11/1495.full SO - J Nucl Med2021 Nov 01; 62 AB - Encouraging results from targeted α-therapy have received significant attention from academia and industry. However, the limited availability of suitable radionuclides has hampered widespread translation and application. In the present review, we discuss the most promising candidates for clinical application and the state of the art of their production and supply. In this review, along with 2 forthcoming reviews on chelation and clinical application of α-emitting radionuclides, The Journal of Nuclear Medicine will provide a comprehensive assessment of the field.