TY - JOUR T1 - <sup>18</sup>F-6-Fluoro-<span class="sc">l</span>-Dopa PET/CT Imaging of Congenital Hyperinsulinism JF - Journal of Nuclear Medicine JO - J Nucl Med SP - 51S LP - 56S DO - 10.2967/jnumed.120.246033 VL - 62 IS - Supplement 2 AU - Lisa J. States AU - J. Christopher Davis AU - Steven M. Hamel AU - Susan A. Becker AU - Hongming Zhuang Y1 - 2021/07/01 UR - http://jnm.snmjournals.org/content/62/Supplement_2/51S.abstract N2 - Congenital hyperinsulinism is characterized by persistent hypoglycemia due to inappropriate excess secretion of insulin resulting in hyperinsulinemic hypoglycemia. The clinical course varies from mild to severe, with a significant risk for brain damage. Imaging plays a valuable role in the care of infants and children with severe hypoglycemia unresponsive to medical therapy. 18F-6-fluoro-l-dopa PET/CT is the method of choice for the detection and localization of a focal lesion of hyperinsulinism. Surgical resection of a focal lesion can lead to a cure with limited pancreatectomy. This article reviews the role of 18F-6-fluoro-l-dopa PET/CT in the management of this vulnerable population. ER -