RT Journal Article
SR Electronic
T1 Image-guided High-Intensity Focused Ultrasound, A Novel Application for Interventional Nuclear Medicine?
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP jnumed.120.256230
DO 10.2967/jnumed.120.256230
A1 Xinrui Zhang
A1 Lisa Landgraf
A1 Nikolaos Bailis
A1 Michael Unger
A1 Thies H. Jochimsen
A1 Andreas Melzer
YR 2021
UL http://jnm.snmjournals.org/content/early/2021/06/04/jnumed.120.256230.abstract
AB Image-guided high-intensity focused ultrasound (HIFU) has been increasingly used in medicine over the past few decades, and several systems for such have become commercially available. HIFU has passed regulatory approval for the ablation of various solid tumors, the treatment of neurological diseases, and the palliative management of bone metastases around the world. The mechanical and thermal effects of focused ultrasound provide a possibility for histotripsy, support radiation therapy, and targeted drug delivery. The integration of imaging modalities into HIFU systems allows for precise temperature monitoring and accurate treatment planning, increasing the safety and efficiency of treatment. Preclinical and clinical results have demonstrated the potential of image-guided HIFU to reduce adverse effects and increase the quality of life postoperatively. Interventional nuclear image-guided HIFU is an attractive noninvasive option for the future.