RT Journal Article
SR Electronic
T1 The Effects of Temperature Change on Tc-99m MAA Radiochemical Purity
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 165
OP 165
VO 62
IS supplement 1
A1 Fatimah Almuallim
A1 Cybil Nielsen
A1 Arielle Knafel
YR 2021
UL http://jnm.snmjournals.org/content/62/supplement_1/165.abstract
AB 165Purpose: The purpose of this study was to evaluate whether significant temperature changes on Tc99m-MAA can affect the radiochemical purity. Methods: This was a prospective study. Sixty one samples were obtained including the control sample, each was around 18.5 megabecquerel. All Samples were tested for radiochemical purity before and after temperature change and the results were analyzed using a two sample, paired t-test. Samples were divided into four groups of 15 samples. The first group was heated in a 49 C° bath for 15 minutes, the second group was frozen for 15 minutes, the Third group was heated in a 49 C° bath for 90 minutes, and the fourth group was frozen for 90 minutes. After all samples thawed to room temperature, they were tested for radiochemical purity using saline and silica gel strips. The control sample was tested four times with each group. Results: The control sample had an average radiochemical purity of 98.9% for the four times it was tested. All four groups had an average of 99% radiochemical purity, with a p-value of 0.2 indicating that no changes had occurred in the radiochemical purity of all samples after temperature changes. Conclusions: Temperature changes do not affect the radiochemical purity of Tc99m-MAA.