Fibroblast Activation Protein–Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial

¹Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
²Institute of Diagnostic and Interventional Radiology and Neuroradiology, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
³German Cancer Consortium, Partner Site Essen, Essen, Germany;
⁴Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
⁵Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Essen, Germany;
⁶Division of Solid Tumor Translational Oncology, German Cancer Consortium, Partner Site Essen, Essen, Germany;
⁷German Cancer Research Center, Heidelberg, Germany;
⁸Department of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
⁹Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria;
¹⁰Division of Thoracic Surgery, Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;
¹¹National Center for Tumor Diseases, Dresden, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; and Helmholtz-Zentrum Dresden–Rossendorf, Dresden, Germany;
¹²Department of Pulmonary Medicine, Section of Interventional Pulmonology, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
¹³Department of Radiotherapy, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
¹⁴Institute of Pathology, University Hospital Essen, University of Duisburg–Essen, Essen, Germany; and
¹⁵Division of Thoracic Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg–Essen, Essen, Germany