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Research ArticleClinical Investigation

PET Imaging and Protein Expression of Prostate-Specific Membrane Antigen in Glioblastoma: A Multicenter Inventory Study

Sanne A.M. van Lith, Ilanah J. Pruis, Nelleke Tolboom, Tom J. Snijders, Dylan Henssen, Mark ter Laan, Maarten te Dorsthorst, William P.J. Leenders, Martin Gotthardt, James Nagarajah, Pierre A. Robe, Philip De Witt Hamer, Harry Hendrikse, Daniela E. Oprea-Lager, Maqsood Yaqub, Ronald Boellaard, Pieter Wesseling, Rutger K. Balvers, Frederik A. Verburg, Anita A. Harteveld, Marion Smits, Martin van den Bent, Sophie E.M. Veldhuijzen van Zanten and Elsmarieke van de Giessen
Journal of Nuclear Medicine August 2023, jnumed.123.265738; DOI: https://doi.org/10.2967/jnumed.123.265738
Sanne A.M. van Lith
1Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands;
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Ilanah J. Pruis
2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
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Nelleke Tolboom
3Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands;
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Tom J. Snijders
4Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands;
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Dylan Henssen
1Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands;
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Mark ter Laan
5Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands;
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Maarten te Dorsthorst
5Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands;
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William P.J. Leenders
6Biochemistry, Radboud University Medical Center, Nijmegen, The Netherlands;
7Predica Diagnostics, Nijmegen, The Netherlands;
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Martin Gotthardt
1Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands;
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James Nagarajah
1Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands;
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Pierre A. Robe
4Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands;
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Philip De Witt Hamer
8Neurosurgery, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Harry Hendrikse
9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Daniela E. Oprea-Lager
9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Maqsood Yaqub
9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Ronald Boellaard
9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Pieter Wesseling
10Pathology, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
11Pathology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;
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Rutger K. Balvers
12Neurosurgery, Erasmus MC, Rotterdam, The Netherlands;
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Frederik A. Verburg
2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
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Anita A. Harteveld
2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
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Marion Smits
2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
13Medical Delta, Delft, The Netherlands; and
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Martin van den Bent
14Brain Tumor Center at Erasmus MC Cancer Institute, Erasmus MC, Rotterdam, The Netherlands
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Sophie E.M. Veldhuijzen van Zanten
2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
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Elsmarieke van de Giessen
9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
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Article Information

jnumed.123.265738
DOI 
https://doi.org/10.2967/jnumed.123.265738
PubMed 
37652540

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication March 16, 2023
  • Revision received May 31, 2023
  • Published online August 31, 2023.

Article Versions

  • You are currently viewing a previous version of this article (August 31, 2023 - 06:21).
  • View the most recent version of this article
Copyright & Usage 
© 2023 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Sanne A.M. van Lith*,1,
  2. Ilanah J. Pruis*,2,
  3. Nelleke Tolboom3,
  4. Tom J. Snijders4,
  5. Dylan Henssen1,
  6. Mark ter Laan5,
  7. Maarten te Dorsthorst5,
  8. William P.J. Leenders6,7,
  9. Martin Gotthardt1,
  10. James Nagarajah1,
  11. Pierre A. Robe4,
  12. Philip De Witt Hamer8,
  13. Harry Hendrikse9,
  14. Daniela E. Oprea-Lager9,
  15. Maqsood Yaqub9,
  16. Ronald Boellaard9,
  17. Pieter Wesseling10,11,
  18. Rutger K. Balvers12,
  19. Frederik A. Verburg2,
  20. Anita A. Harteveld2,
  21. Marion Smits2,13,
  22. Martin van den Bent14,
  23. Sophie E.M. Veldhuijzen van Zanten*,2 and
  24. Elsmarieke van de Giessen*,9
  1. 1Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands;
  2. 2Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands;
  3. 3Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands;
  4. 4Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands;
  5. 5Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands;
  6. 6Biochemistry, Radboud University Medical Center, Nijmegen, The Netherlands;
  7. 7Predica Diagnostics, Nijmegen, The Netherlands;
  8. 8Neurosurgery, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
  9. 9Radiology and Nuclear Medicine, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
  10. 10Pathology, Amsterdam UMC, VUmc, Amsterdam, The Netherlands;
  11. 11Pathology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;
  12. 12Neurosurgery, Erasmus MC, Rotterdam, The Netherlands;
  13. 13Medical Delta, Delft, The Netherlands; and
  14. 14Brain Tumor Center at Erasmus MC Cancer Institute, Erasmus MC, Rotterdam, The Netherlands
  1. For correspondence or reprints, contact Sophie Veldhuijzen E.M. van Zanten (s.veldhuijzenvanzanten{at}erasmusmc.nl).
  1. ↵* Contributed equally to this work.

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PET Imaging and Protein Expression of Prostate-Specific Membrane Antigen in Glioblastoma: A Multicenter Inventory Study
Sanne A.M. van Lith, Ilanah J. Pruis, Nelleke Tolboom, Tom J. Snijders, Dylan Henssen, Mark ter Laan, Maarten te Dorsthorst, William P.J. Leenders, Martin Gotthardt, James Nagarajah, Pierre A. Robe, Philip De Witt Hamer, Harry Hendrikse, Daniela E. Oprea-Lager, Maqsood Yaqub, Ronald Boellaard, Pieter Wesseling, Rutger K. Balvers, Frederik A. Verburg, Anita A. Harteveld, Marion Smits, Martin van den Bent, Sophie E.M. Veldhuijzen van Zanten, Elsmarieke van de Giessen
Journal of Nuclear Medicine Aug 2023, jnumed.123.265738; DOI: 10.2967/jnumed.123.265738

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PET Imaging and Protein Expression of Prostate-Specific Membrane Antigen in Glioblastoma: A Multicenter Inventory Study
Sanne A.M. van Lith, Ilanah J. Pruis, Nelleke Tolboom, Tom J. Snijders, Dylan Henssen, Mark ter Laan, Maarten te Dorsthorst, William P.J. Leenders, Martin Gotthardt, James Nagarajah, Pierre A. Robe, Philip De Witt Hamer, Harry Hendrikse, Daniela E. Oprea-Lager, Maqsood Yaqub, Ronald Boellaard, Pieter Wesseling, Rutger K. Balvers, Frederik A. Verburg, Anita A. Harteveld, Marion Smits, Martin van den Bent, Sophie E.M. Veldhuijzen van Zanten, Elsmarieke van de Giessen
Journal of Nuclear Medicine Aug 2023, jnumed.123.265738; DOI: 10.2967/jnumed.123.265738
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Keywords

  • Glioblastoma
  • prostate-specific membrane antigen (PSMA)
  • PET
  • immunohistochemistry
  • RNA sequencing
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