The Impact of Radiobiologically-Informed Dose Prescription on the Clinical Benefit of Yttrium-90 SIRT in Colorectal Cancer Patients

Elliot M Abbott; Nadia Falzone; Boon Q Lee; Christiana Kartsonaki; Helen Winter; Tessa A Greenhalgh; Daniel R McGowan; Nigar Syed; Ana M Denis-Bacelar; Philip Boardman; Ricky A Sharma; Katherine Anne Vallis

doi:10.2967/jnumed.119.233650

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The Impact of Radiobiologically-Informed Dose Prescription on the Clinical Benefit of Yttrium-90 SIRT in Colorectal Cancer Patients

Elliot M Abbott, Nadia Falzone, Boon Q Lee, Christiana Kartsonaki, Helen Winter, Tessa A Greenhalgh, Daniel R McGowan, Nigar Syed, Ana M Denis-Bacelar, Philip Boardman, Ricky A Sharma and Katherine Anne Vallis

Journal of Nuclear Medicine May 2020, jnumed.119.233650; DOI: https://doi.org/10.2967/jnumed.119.233650

Elliot M Abbott

1 University of Oxford, United Kingdom;

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Nadia Falzone

1 University of Oxford, United Kingdom;

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Boon Q Lee

1 University of Oxford, United Kingdom;

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Christiana Kartsonaki

1 University of Oxford, United Kingdom;

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Helen Winter

2 Oxford University Hospitals NHS Foundation Trust, United Kingdom;

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Tessa A Greenhalgh

2 Oxford University Hospitals NHS Foundation Trust, United Kingdom;

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Daniel R McGowan

2 Oxford University Hospitals NHS Foundation Trust, United Kingdom;

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Nigar Syed

3 Department of Radiology, Oxford University Hospitals NHS Foundation Trust, United Kingdom;

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Ana M Denis-Bacelar

4 National Physical Laboratory, United Kingdom;

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Philip Boardman

3 Department of Radiology, Oxford University Hospitals NHS Foundation Trust, United Kingdom;

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Ricky A Sharma

5 University College London, United Kingdom

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Katherine Anne Vallis

1 University of Oxford, United Kingdom;

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April 1, 2025

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The Impact of Radiobiologically-Informed Dose Prescription on the Clinical Benefit of Yttrium-90 SIRT in Colorectal Cancer Patients

Journal of Nuclear Medicine May 2020, jnumed.119.233650; DOI: 10.2967/jnumed.119.233650

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The Impact of Radiobiologically-Informed Dose Prescription on the Clinical Benefit of Yttrium-90 SIRT in Colorectal Cancer Patients

Journal of Nuclear Medicine May 2020, jnumed.119.233650; DOI: 10.2967/jnumed.119.233650

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Keywords

Oncology: Liver
radiobiology/dosimetry
radionuclide therapy
BED
colorectal cancer
liver metastases
SIRT
Yttrium-90

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