First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic 68Ga-FAPI-04 PET in Pancreatic and Gastric Cancer

Ruohua Chen; Xinlan Yang; Yee Ling Ng; Xiaofeng Yu; Yanmiao Huo; Xiuying Xiao; Chenpeng Zhang; Yumei Chen; Chaojie Zheng; Lianghua Li; Gang Huang; Yun Zhou; Jianjun Liu

doi:10.2967/jnumed.122.264988

Research ArticleClinical Investigation

First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic ⁶⁸Ga-FAPI-04 PET in Pancreatic and Gastric Cancer

Ruohua Chen, Xinlan Yang, Yee Ling Ng, Xiaofeng Yu, Yanmiao Huo, Xiuying Xiao, Chenpeng Zhang, Yumei Chen, Chaojie Zheng, Lianghua Li, Gang Huang, Yun Zhou and Jianjun Liu

Journal of Nuclear Medicine June 2023, 64 (6) 960-967; DOI: https://doi.org/10.2967/jnumed.122.264988

Ruohua Chen

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Xinlan Yang

4Central Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China;

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Yee Ling Ng

4Central Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China;

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Xiaofeng Yu

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Yanmiao Huo

5Department of Biliary-Pancreatic Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; and

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Xiuying Xiao

6Department of Oncology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

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Chenpeng Zhang

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Yumei Chen

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Chaojie Zheng

4Central Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China;

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Lianghua Li

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Gang Huang

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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Yun Zhou

4Central Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China;

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Jianjun Liu

1Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

2Institute of Clinical Nuclear Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

3Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, China;

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First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic ⁶⁸Ga-FAPI-04 PET in Pancreatic and Gastric Cancer

Ruohua Chen, Xinlan Yang, Yee Ling Ng, Xiaofeng Yu, Yanmiao Huo, Xiuying Xiao, Chenpeng Zhang, Yumei Chen, Chaojie Zheng, Lianghua Li, Gang Huang, Yun Zhou, Jianjun Liu

Journal of Nuclear Medicine Jun 2023, 64 (6) 960-967; DOI: 10.2967/jnumed.122.264988

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First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic ⁶⁸Ga-FAPI-04 PET in Pancreatic and Gastric Cancer

Ruohua Chen, Xinlan Yang, Yee Ling Ng, Xiaofeng Yu, Yanmiao Huo, Xiuying Xiao, Chenpeng Zhang, Yumei Chen, Chaojie Zheng, Lianghua Li, Gang Huang, Yun Zhou, Jianjun Liu

Journal of Nuclear Medicine Jun 2023, 64 (6) 960-967; DOI: 10.2967/jnumed.122.264988

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The Role of Total-Body PET in Drug Development and Evaluation: Status and Outlook
Clinical Implementation of Total-Body PET in China

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Keywords

pancreatic cancer
68Ga-FAPI-04
parametric imaging
kinetic modeling
total-body dynamic PET imaging

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First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic ⁶⁸Ga-FAPI-04 PET in Pancreatic and Gastric Cancer

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