Initial Results of 68Ga-FAPI-46 PET/MRI to Assess Response to Neoadjuvant Chemotherapy in Breast Cancer

Philipp Backhaus; Matthias C. Burg; Inga Asmus; Michaela Pixberg; Florian Büther; Hans-Jörg Breyholz; Randy Yeh; Stefanie B. Weigel; Patricia Stichling; Walter Heindel; Stefanie Bobe; Peter Barth; Joke Tio; Michael Schäfers

doi:10.2967/jnumed.122.264871

Research ArticleClinical Investigation

Initial Results of ⁶⁸Ga-FAPI-46 PET/MRI to Assess Response to Neoadjuvant Chemotherapy in Breast Cancer

Philipp Backhaus, Matthias C. Burg, Inga Asmus, Michaela Pixberg, Florian Büther, Hans-Jörg Breyholz, Randy Yeh, Stefanie B. Weigel, Patricia Stichling, Walter Heindel, Stefanie Bobe, Peter Barth, Joke Tio and Michael Schäfers

Journal of Nuclear Medicine May 2023, 64 (5) 717-723; DOI: https://doi.org/10.2967/jnumed.122.264871

Philipp Backhaus

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Matthias C. Burg

4Clinic for Radiology, University Hospital Münster, Münster, Germany;

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Inga Asmus

1Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;

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Michaela Pixberg

1Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;

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Florian Büther

1Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;

2European Institute for Molecular Imaging, University of Münster, Münster, Germany;

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Hans-Jörg Breyholz

1Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;

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Randy Yeh

3Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York City, New York;

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Stefanie B. Weigel

4Clinic for Radiology, University Hospital Münster, Münster, Germany;

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Patricia Stichling

4Clinic for Radiology, University Hospital Münster, Münster, Germany;

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Walter Heindel

4Clinic for Radiology, University Hospital Münster, Münster, Germany;

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Stefanie Bobe

2European Institute for Molecular Imaging, University of Münster, Münster, Germany;

5Gerhard-Domagk Institute for Pathology, University of Münster, Münster, Germany; and

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Peter Barth

5Gerhard-Domagk Institute for Pathology, University of Münster, Münster, Germany; and

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Joke Tio

6Department of Gynecology and Obstetrics, University Hospital Münster, Münster, Germany

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Michael Schäfers

1Department of Nuclear Medicine, University Hospital Münster, Münster, Germany;

2European Institute for Molecular Imaging, University of Münster, Münster, Germany;

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Journal of Nuclear Medicine

Vol. 64, Issue 5

May 1, 2023

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Initial Results of ⁶⁸Ga-FAPI-46 PET/MRI to Assess Response to Neoadjuvant Chemotherapy in Breast Cancer

Journal of Nuclear Medicine May 2023, 64 (5) 717-723; DOI: 10.2967/jnumed.122.264871

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Initial Results of ⁶⁸Ga-FAPI-46 PET/MRI to Assess Response to Neoadjuvant Chemotherapy in Breast Cancer

Journal of Nuclear Medicine May 2023, 64 (5) 717-723; DOI: 10.2967/jnumed.122.264871

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Predicting Pathologic Complete Response in Locally Advanced Rectal Cancer with [68Ga]Ga-FAPI-04 PET, [18F]FDG PET, and Contrast-Enhanced MRI: Lesion-to-Lesion Comparison with Pathology
[18F]AlF-NOTA-FAPI-04 PET/CT for Predicting Pathologic Response of Resectable Esophageal Squamous Cell Carcinoma to Neoadjuvant Camrelizumab and Chemotherapy: A Phase II Clinical Trial
68Ga-Labeled Fibroblast Activation Protein Inhibitor PET/CT for the Early and Late Prediction of Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Prospective Study

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Keywords

FAPI
PET/MRI
breast cancer
neoadjuvant chemotherapy
deescalation

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