Abstract
4089
Introduction: For gastric emptying (GE) studies the purpose of this research was to determine if there was a difference in tagging efficiency of unfiltered 99mTc-sulfur colloid and filtered 99mTc-sulfur colloid to eggbeaters.
Methods: Two separate "meals" were prepared, one with filtered 99mTc-sulfur colloid and the other with unfiltered 99mTc-sulfur colloid, tagged to eggbeaters. They were split into ten samples each (n = 20) and assayed in a dose calibrator. Five mL of saline were added to all 20 samples to "wash" any unbound 99mTcO4-. Then, the samples were capped, secured, and centrifuged for two minutes. The samples were then counted in a well counter with the solid and liquid combined. The liquid was removed from the solid and then counted separately. This was repeated for all 20 samples, using a new syringe and vial each time. Each sample was calculated for percent tagging efficiency. A two-sample unpaired t-test was performed to compare tagging efficiency between unfiltered and filtered groups.
Results: Tagging efficiency was higher unfiltered 99mTc-sulfur colloid(94.5%) than filtered 99mTc-sulfur colloid (91.8%), with a P-value of 0.004.
Conclusions: There is a difference of tagging efficiency between unfiltered 99mTc-sulfur colloid and filtered 99mTc-sulfur colloid to eggbeaters.