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Journal of Nuclear Medicine

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Table of Contents

July 1, 2022; Volume 63,Issue 7

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 10A;

Editor's Page

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    More Unacceptable Denials: Now It’s PSMA-Targeted PET/CT Imaging
    Johannes Czernin, Thaiza Adams and Jeremie Calais
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 969-970; DOI: https://doi.org/10.2967/jnumed.121.264374

The State of The Art

  • Open Access
    Molecular Imaging Findings on Acute and Long-Term Effects of COVID-19 on the Brain: A Systematic Review
    Philipp T. Meyer, Sabine Hellwig, Ganna Blazhenets and Jonas A. Hosp
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 971-980; DOI: https://doi.org/10.2967/jnumed.121.263085

Standard of Care

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    Alzheimer Disease: Standard of Diagnosis, Treatment, Care, and Prevention
    Stefan Teipel, Deborah Gustafson, Rik Ossenkoppele, Oskar Hansson, Claudio Babiloni, Michael Wagner, Steffi G. Riedel-Heller, Ingo Kilimann and Yi Tang
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 981-985; DOI: https://doi.org/10.2967/jnumed.121.262239

Continuing Education

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    Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 2: Inflammation, Fibrosis, Thrombosis, Calcification, and Amyloidosis Imaging
    John C. Stendahl, Jennifer M. Kwan, Darko Pucar and Mehran M. Sadeghi
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 986-994; DOI: https://doi.org/10.2967/jnumed.121.263507

Special Contribution

  • Female Authors in Nuclear Medicine Journals: A Survey from 2014 to 2020
    Open Access
    Female Authors in Nuclear Medicine Journals: A Survey from 2014 to 2020
    Charline Lasnon, Gilles Girault, Rachida Lebtahi, Catherine Ansquer, Justine Lequesne and Elske Quak
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 995-1000; DOI: https://doi.org/10.2967/jnumed.121.262773

Oncology

  • Clinical

    • <sup>18</sup>F-FDG PET Improves Baseline Clinical Predictors of Response in Diffuse Large B-Cell Lymphoma: The HOVON-84 Study
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      18F-FDG PET Improves Baseline Clinical Predictors of Response in Diffuse Large B-Cell Lymphoma: The HOVON-84 Study
      Coreline N. Burggraaff, Jakoba J. Eertink, Pieternella J. Lugtenburg, Otto S. Hoekstra, Anne I.J. Arens, Bart de Keizer, Martijn W. Heymans, Bronno van der Holt, Sanne E. Wiegers, Simone Pieplenbosch, Ronald Boellaard, Henrica C.W. de Vet, Josée M. Zijlstra and on behalf of the HOVON Imaging Working Group and the HOVON Lymphoma Working Group
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1001-1007; DOI: https://doi.org/10.2967/jnumed.121.262205
    • Molecular Signature of <sup>18</sup>F-FDG PET Biomarkers in Newly Diagnosed Multiple Myeloma Patients: A Genome-Wide Transcriptome Analysis from the CASSIOPET Study
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      Molecular Signature of 18F-FDG PET Biomarkers in Newly Diagnosed Multiple Myeloma Patients: A Genome-Wide Transcriptome Analysis from the CASSIOPET Study
      Jean-Baptiste Alberge, Françoise Kraeber-Bodéré, Bastien Jamet, Cyrille Touzeau, Hélène Caillon, Soraya Wuilleme, Marie-Christine Béné, Tobias Kampfenkel, Pieter Sonneveld, Mark van Duin, Herve Avet-Loiseau, Jill Corre, Florence Magrangeas, Thomas Carlier, Caroline Bodet-Milin, Michel Chérel, Philippe Moreau, Stéphane Minvielle and Clément Bailly
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1008-1013; DOI: https://doi.org/10.2967/jnumed.121.262884

Theranostics

  • Clinical

    • Prognostic Value of Whole-Body PET Volumetric Parameters Extracted from <sup>68</sup>Ga-DOTATOC PET/CT in Well-Differentiated Neuroendocrine Tumors
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      Prognostic Value of Whole-Body PET Volumetric Parameters Extracted from 68Ga-DOTATOC PET/CT in Well-Differentiated Neuroendocrine Tumors
      Philippe Thuillier, Virginia Liberini, Serena Grimaldi, Osvaldo Rampado, Elena Gallio, Bruno De Santi, Emanuela Arvat, Alessandro Piovesan, Roberto Filippi, Ronan Abgral, Filippo Molinari and Désirée Deandreis
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1014-1020; DOI: https://doi.org/10.2967/jnumed.121.262652
    • Correlation of <sup>68</sup>Ga-FAPi-46 PET Biodistribution with FAP Expression by Immunohistochemistry in Patients with Solid Cancers: Interim Analysis of a Prospective Translational Exploratory Study
      Open Access
      Correlation of 68Ga-FAPi-46 PET Biodistribution with FAP Expression by Immunohistochemistry in Patients with Solid Cancers: Interim Analysis of a Prospective Translational Exploratory Study
      Christine E. Mona, Matthias R. Benz, Firas Hikmat, Tristan R. Grogan, Katharina Lueckerath, Aria Razmaria, Rana Riahi, Roger Slavik, Mark D. Girgis, Giuseppe Carlucci, Kimberly A. Kelly, Samuel W. French, Johannes Czernin, David W. Dawson and Jeremie Calais
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1021-1026; DOI: https://doi.org/10.2967/jnumed.121.262426
    • The Quest for an Accurate Functional Tumor Volume with <sup>68</sup>Ga-DOTATATE PET/CT
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      The Quest for an Accurate Functional Tumor Volume with 68Ga-DOTATATE PET/CT
      Ryan P. Reddy, C. Ross Schmidtlein, Romina G. Giancipoli, Audrey Mauguen, Daniel LaFontaine, Heiko Schoder and Lisa Bodei
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1027-1032; DOI: https://doi.org/10.2967/jnumed.121.262782

Radionuclide Therapy

  • Basic

    • Glypican-3–Targeted <sup>227</sup>Th <strong>α</strong>-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma
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      Glypican-3–Targeted 227Th α-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma
      Kevin P. Labadie, Donald K. Hamlin, Aimee Kenoyer, Sara K. Daniel, Alan F. Utria, Andrew D. Ludwig, Heidi L. Kenerson, Lily Li, Jonathan G. Sham, Delphine L. Chen, Johnnie J. Orozco, Raymond S. Yeung, Chris Orvig, Yawen Li, D. Scott Wilbur and James O. Park
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1033-1038; DOI: https://doi.org/10.2967/jnumed.121.262562
    • Enhancing <sup>223</sup>Ra Treatment Efficacy by Anti-<strong>β</strong>1 Integrin Targeting
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      Enhancing 223Ra Treatment Efficacy by Anti-β1 Integrin Targeting
      Claudia Paindelli, Stefano Casarin, Feng Wang, Luis Diaz-Gomez, Jianhua Zhang, Antonios G. Mikos, Christopher J. Logothetis, Peter Friedl and Eleonora Dondossola
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1039-1045; DOI: https://doi.org/10.2967/jnumed.121.262743
    • FEATURED BASIC SCIENCE ARTICLE

      • Affibody-Mediated PNA-Based Pretargeted Cotreatment Improves Survival of Trastuzumab-Treated Mice Bearing HER2-Expressing Xenografts
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        Affibody-Mediated PNA-Based Pretargeted Cotreatment Improves Survival of Trastuzumab-Treated Mice Bearing HER2-Expressing Xenografts
        Maryam Oroujeni, Hanna Tano, Anzhelika Vorobyeva, Yongsheng Liu, Olga Vorontsova, Tianqi Xu, Kristina Westerlund, Anna Orlova, Vladimir Tolmachev and Amelie Eriksson Karlström
        Journal of Nuclear Medicine July 1, 2022, 63 (7) 1046-1051; DOI: https://doi.org/10.2967/jnumed.121.262123

Neurology

  • Clinical

    • In Vivo <sup>18</sup>F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy
      Open Access
      In Vivo 18F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy
      Maura Malpetti, Sanne S. Kaalund, Kamen A. Tsvetanov, Timothy Rittman, Mayen Briggs, Kieren S.J. Allinson, Luca Passamonti, Negin Holland, P. Simon Jones, Tim D. Fryer, Young T. Hong, Antonina Kouli, W. Richard Bevan-Jones, Elijah Mak, George Savulich, Maria Grazia Spillantini, Franklin I. Aigbirhio, Caroline H. Williams-Gray, John T. O’Brien and James B. Rowe
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1052-1057; DOI: https://doi.org/10.2967/jnumed.121.262985
    • Open Access
      Neuropsychologic Profiles and Cerebral Glucose Metabolism in Neurocognitive Long COVID Syndrome
      Andrea Dressing, Tobias Bormann, Ganna Blazhenets, Nils Schroeter, Lea I. Walter, Johannes Thurow, Dietrich August, Hanna Hilger, Katarina Stete, Kathrin Gerstacker, Susan Arndt, Alexander Rau, Horst Urbach, Siegbert Rieg, Dirk Wagner, Cornelius Weiller, Philipp T. Meyer and Jonas A. Hosp
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1058-1063; DOI: https://doi.org/10.2967/jnumed.121.262677

Cardiovascular

  • Clinical

    • FEATURED ARTICLE OF THE MONTH

      • Independent Prognostic Utility of <sup>11</sup>C-Pittsburgh Compound B PET in Patients with Light-Chain Cardiac Amyloidosis
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        Independent Prognostic Utility of 11C-Pittsburgh Compound B PET in Patients with Light-Chain Cardiac Amyloidosis
        You-Jung Choi, Youngil Koh, Hyun-Jung Lee, In-Chang Hwang, Jun-Bean Park, Yeonyee E. Yoon, Hack-Lyoung Kim, Hyung-Kwan Kim, Yong-Jin Kim, Goo-Yeong Cho, Dae-Won Sohn, Jin-Chul Paeng and Seung-Pyo Lee
        Journal of Nuclear Medicine July 1, 2022, 63 (7) 1064-1069; DOI: https://doi.org/10.2967/jnumed.121.263033

Pulmonary/Covid

  • Clinical

    • Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients: A Multicenter Study
      Open Access
      Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients: A Multicenter Study
      Pierre-Yves Le Roux, Pierre-Benoit Bonnefoy, Achraf Bahloul, Benoit Denizot, Bertrand Barres, Caroline Moreau-Triby, Astrid Girma, Amandine Pallardy, Quentin Ceyrat, Laure Sarda-Mantel, Micheline Razzouk-Cadet, Reka Zsigmond, Cachin Florent, Gilles Karcher and Pierre-Yves Salaun
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1070-1074; DOI: https://doi.org/10.2967/jnumed.121.262955
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      Lung Dose Measured on Postradioembolization 90Y PET/CT and Incidence of Radiation Pneumonitis
      Martina Stella, Rob van Rooij, Marnix G.E.H. Lam, Hugo W.A.M. de Jong and Arthur J.A.T. Braat
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1075-1080; DOI: https://doi.org/10.2967/jnumed.121.263143

Endocrinology

  • Clinical

    • Diagnostic Performance of Cervical Ultrasound, <sup>99m</sup>Tc-Sestamibi Scintigraphy, and Contrast-Enhanced <sup>18</sup>F-Fluorocholine PET in Primary Hyperparathyroidism
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      Diagnostic Performance of Cervical Ultrasound, 99mTc-Sestamibi Scintigraphy, and Contrast-Enhanced 18F-Fluorocholine PET in Primary Hyperparathyroidism
      Vincent Boudousq, Nicolas Guignard, Olivier Gilly, Benjamin Chambert, Adel Mamou, Olivier Moranne, Mathilde Zemmour, Haitham Sharara and Benjamin Lallemant
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1081-1086; DOI: https://doi.org/10.2967/jnumed.121.261900

AI/Advanced Image Analysis

  • Clinical

    • Improved Prognosis of Treatment Failure in Cervical Cancer with Nontumor PET/CT Radiomics
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      Improved Prognosis of Treatment Failure in Cervical Cancer with Nontumor PET/CT Radiomics
      Tahir I. Yusufaly, Jingjing Zou, Tyler J. Nelson, Casey W. Williamson, Aaron Simon, Meenakshi Singhal, Hannah Liu, Hank Wong, Cheryl C. Saenz, Jyoti Mayadev, Michael T. McHale, Catheryn M. Yashar, Ramez Eskander, Andrew Sharabi, Carl K. Hoh, Sebastian Obrzut and Loren K. Mell
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1087-1093; DOI: https://doi.org/10.2967/jnumed.121.262618

Radiobiology/Dosimetry

  • Clinical

    • Biodistribution and Radiation Dosimetry of Intraperitoneally Administered <sup>124</sup>I-Omburtamab in Patients with Desmoplastic Small Round Cell Tumors
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      Biodistribution and Radiation Dosimetry of Intraperitoneally Administered 124I-Omburtamab in Patients with Desmoplastic Small Round Cell Tumors
      Milan Grkovski, Shakeel Modak, Pat B. Zanzonico, Jorge A. Carrasquillo, Steven M. Larson, John L. Humm and Neeta Pandit-Taskar
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1094-1100; DOI: https://doi.org/10.2967/jnumed.121.262793
  • Translational

    • Radioembolization Dosimetry with Total-Body <sup>90</sup>Y PET
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      Radioembolization Dosimetry with Total-Body 90Y PET
      Gustavo Costa, Benjamin Spencer, Negar Omidvari, Cameron Foster, Michael Rusnak, Heather Hunt, Denise T. Caudle, Rex T. Pillai, Catherine Tram Vu and Emilie Roncali
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1101-1107; DOI: https://doi.org/10.2967/jnumed.121.263145
  • Basic

    • Toward a Patient-Specific Traceable Quantification of SPECT/CT-Based Radiopharmaceutical Distributions
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      Toward a Patient-Specific Traceable Quantification of SPECT/CT-Based Radiopharmaceutical Distributions
      Anna-Lena Theisen, Michael Lassmann and Johannes Tran-Gia
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 1108-1116; DOI: https://doi.org/10.2967/jnumed.121.262925

Special Contribution

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    Proceedings: PET Drugs—A Workshop on Inspections Management and Regulatory Considerations
    Sue Bunning, Christopher Ignace, Steve Mattmuller, Sally W. Schwarz, Peter J.H. Scott, Henry F. VanBrocklin, Steven S. Zigler and on behalf of the Coalition of Drug Manufacturers
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 1117-1123; DOI: https://doi.org/10.2967/jnumed.121.263443

Letters to the Editor

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    Tumor Sink Effect: Myth or Reality?
    Andrei Gafita, Jeremie Calais, Wolfgang P. Fendler and Matthias Eiber
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 1124; DOI: https://doi.org/10.2967/jnumed.122.264119
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    Thoughts on “Tumor Sink Effect in 68Ga-PSMA-11 PET: Myth or Reality?”
    Bastiaan M. Privé, Steffie M.B. Peters, Maike J.M. Uijen, Marcel J.R. Janssen, Willemijn A.M. van Gemert, Michael C. Kreissl, Samer Ezzidin, Mark W. Konijnenberg and James Nagarajah
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 1124-1125; DOI: https://doi.org/10.2967/jnumed.122.263802

Departments

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      Recruitment
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 13A;
    • You have access
      Errata
      Journal of Nuclear Medicine July 1, 2022, 63 (7) 100-1000;

SNMMI Newsline

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    SNMMI Newsline
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 15N-26N;
  • You have access
    Iagaru Receives First Sam Gambhir Trailblazer Award
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 15N;
  • You have access
    SNMMI Honors New Fellows for 2022
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 15N;
  • You have access
    SNMMI Image of the Year 2022: PET/CT Biomarker Predicts Post-MI Cardiac Remodeling
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 16N;
  • You have access
    New Officers for SNMMI and SNMMI-TS
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 17N-18N;
  • You have access
    Recognition of the ABNM by the NRC
    George Segall
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 19N;
  • You have access
    SNMMI Leadership Update: Opportunities for Growth in Nuclear Medicine and Molecular Imaging
    Munir Ghesani
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 20N;
  • You have access
    Newsbriefs
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 21N-26N;
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    From the Literature
    Journal of Nuclear Medicine July 1, 2022, 63 (7) 23N-26N;
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In this issue

Journal of Nuclear Medicine: 63 (7)
Journal of Nuclear Medicine
Vol. 63, Issue 7
July 1, 2022
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Complete Issue (PDF)

Issue highlights

  • Independent Prognostic Utility of 11C-Pittsburgh Compound B PET in Patients with Light-Chain Cardiac Amyloidosis
  • Affibody-Mediated PNA-Based Pretargeted Cotreatment Improves Survival of Trastuzumab-Treated Mice Bearing HER2-Expressing Xenografts
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    • Basic
      • FEATURED BASIC SCIENCE ARTICLE
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    • Clinical
      • FEATURED ARTICLE OF THE MONTH
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  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Autoimmune Encephalitis Concomitant with SARS-CoV-2 Infection: Insight from 18F-FDG PET Imaging and Neuronal Autoantibodies
  • Slow but Evident Recovery from Neocortical Dysfunction and Cognitive Impairment in a Series of Chronic COVID-19 Patients
  • Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View
  • Impact of 68Ga-PSMA-11 PET on the Management of Recurrent Prostate Cancer in a Prospective Single-Arm Clinical Trial
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