Journal of Nuclear Medicine: 63 (3)

March 1, 2022; Volume 63,Issue 3

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine March 1, 2022, 63 (3) 10A;

Discussions with Leaders

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Health Care and Nuclear Medicine in France
Dominique Le Guludec, Johannes Czernin and Jérémie Calais

Journal of Nuclear Medicine March 1, 2022, 63 (3) 327-330; DOI: https://doi.org/10.2967/jnumed.122.263863

The State of The Art

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The History of Prostate-Specific Membrane Antigen as a Theranostic Target in Prostate Cancer: The Cornerstone Role of the Prostate Cancer Foundation
Andrea K. Miyahira and Howard R. Soule

Journal of Nuclear Medicine March 1, 2022, 63 (3) 331-338; DOI: https://doi.org/10.2967/jnumed.121.262997

Hot Topics

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The Promise of Metastasis-Directed Therapy for Oligometastatic Prostate Cancer: Going Beneath the Surface with Molecular Imaging
Philip Sutera, Ryan M. Phillips, Matthew Deek, Gokhan Ozyigit, Cem Onal and Phuoc T. Tran

Journal of Nuclear Medicine March 1, 2022, 63 (3) 339-341; DOI: https://doi.org/10.2967/jnumed.121.263684

Continuing Education

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Principles of Tracer Kinetic Analysis in Oncology, Part I: Principles and Overview of Methodology
Austin R. Pantel, Varsha Viswanath, Mark Muzi, Robert K. Doot and David A. Mankoff

Journal of Nuclear Medicine March 1, 2022, 63 (3) 342-352; DOI: https://doi.org/10.2967/jnumed.121.263518

Focus on Molecular Imaging

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Latest Advances in Multimodality Imaging of Aortic Stenosis
Evangelos Tzolos, Jacek Kwiecinski, Daniel Berman, Piotr Slomka, David E. Newby and Marc R. Dweck

Journal of Nuclear Medicine March 1, 2022, 63 (3) 353-358; DOI: https://doi.org/10.2967/jnumed.121.262304

Oncology

Clinical
- INVITED PERSPECTIVE
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    Toward a Better Understanding of Immune Checkpoint Inhibitor Radiolabeled PET Imaging Studies
    Harm Westdorp, Sarah R. Verhoeff, Martin Gotthardt, Carla M.L. van Herpen, Michel M. van, den Heuvel, Sandra Heskamp and Erik H.J.G. Aarntzen
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 359-361; DOI: https://doi.org/10.2967/jnumed.121.262622
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  Study of ⁸⁹Zr-Pembrolizumab PET/CT in Patients With Advanced-Stage Non–Small Cell Lung Cancer
  Anna-Larissa N. Niemeijer, Daniela E. Oprea-Lager, Marc C. Huisman, Otto S. Hoekstra, Ronald Boellaard, Berlinda J. de Wit-van der Veen, Idris Bahce, Daniëlle J. Vugts, Guus A.M.S. van Dongen, Erik Thunnissen, Egbert F. Smit and Adrianus J. de Langen
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 362-367; DOI: https://doi.org/10.2967/jnumed.121.261926
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  Functional Characterization of Adrenocortical Masses in Nononcologic Patients Using ⁶⁸Ga-Pentixafor
  Jie Ding, Anli Tong, Yushi Zhang, Jin Wen, Hui Zhang, Marcus Hacker, Li Huo and Xiang Li
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 368-375; DOI: https://doi.org/10.2967/jnumed.121.261964
- Open Access
  A Randomized, Factorial Phase II Study to Determine the Optimal Dosing Regimen for ⁶⁸Ga-Satoreotide Trizoxetan as an Imaging Agent in Patients with Gastroenteropancreatic Neuroendocrine Tumors
  Irene Virgolini, Shadfar Bahri, Andreas Kjaer, Henning Grønbæk, Peter Iversen, Esben A. Carlsen, Mathias Loft, Ulrich Knigge, Johanna Maffey-Steffan, Christine Powell, Colin G. Miller, Thomas Rohban, Sandy McEwan and Johannes Czernin
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 376-383; DOI: https://doi.org/10.2967/jnumed.121.261936
- BRIEF COMMUNICATION
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    Value of ⁶⁸Ga-DOTATOC and Carbidopa-Assisted ¹⁸F-DOPA PET/CT for Insulinoma Localization
    Alessio Imperiale, Caroline Boursier, Nicolas Sahakian, Eric Ouvrard, Elodie Chevalier, Frédéric Sebag, Pietro Addeo and David Taïeb
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 384-388; DOI: https://doi.org/10.2967/jnumed.121.262401
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  Quantitative Radiomics Features in Diffuse Large B-Cell Lymphoma: Does Segmentation Method Matter?
  Jakoba J. Eertink, Elisabeth A.G. Pfaehler, Sanne E. Wiegers, Tim van, de Brug, Pieternella J. Lugtenburg, Otto S. Hoekstra, Josée M. Zijlstra, Henrica C.W. de Vet and Ronald Boellaard
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 389-395; DOI: https://doi.org/10.2967/jnumed.121.262117

Theranostics

Clinical
- BRIEF COMMUNICATION
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    Response to Combined Peptide Receptor Radionuclide Therapy and Checkpoint Immunotherapy with Ipilimumab Plus Nivolumab in Metastatic Merkel Cell Carcinoma
    Justin Ferdinandus, Wolfgang P. Fendler, Katharina Lueckerath, Christoph Berliner, Sabine Kurzidem, Eva Hadaschik, Joachim Klode, Lisa Zimmer, Elisabeth Livingstone, Dirk Schadendorf, Ken Herrmann, Juergen C. Becker and Selma Ugurel
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 396-398; DOI: https://doi.org/10.2967/jnumed.121.262344
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  Dosimetric Quantities in Neuroendocrine Tumors over Treatment Cycles with ¹⁷⁷Lu-DOTATATE
  Daniel Roth, Johan Gustafsson, Carl Fredrik Warfvinge, Anna Sundlöv, Anna Åkesson, Jan Tennvall and Katarina Sjögreen Gleisner
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 399-405; DOI: https://doi.org/10.2967/jnumed.121.262069
- BRIEF COMMUNICATION
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    Intraarterial Administration Boosts ¹⁷⁷Lu-HA-DOTATATE Accumulation in Salvage Meningioma Patients
    Evert-Jan P.A. Vonken, Rutger C.G. Bruijnen, Tom J. Snijders, Tatjana Seute, Marnix G.E.H. Lam, Bart de Keizer and Arthur J.A.T. Braat
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 406-409; DOI: https://doi.org/10.2967/jnumed.121.262491
- BRIEF COMMUNICATION
  - Open Access
    ¹⁷⁷Lu-Prostate-Specific Membrane Antigen Ligand After ²²³Ra Treatment in Men with Bone-Metastatic Castration-Resistant Prostate Cancer: Real-World Clinical Experience
    Oliver Sartor, Christian la Fougère, Markus Essler, Samer Ezziddin, Gero Kramer, Jörg Ellinger, Luke Nordquist, John Sylvester, Giovanni Paganelli, Avivit Peer, Martin Bögemann, Jeffrey Meltzer, Per Sandström, Frank Verholen and Daniel Y. Song
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 410-414; DOI: https://doi.org/10.2967/jnumed.121.262240
- FEATURED ARTICLE OF THE MONTH
  - Open Access
    Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using ¹⁷⁷Lu-FAP-2286: First-in-Humans Results
    Richard P. Baum, Christiane Schuchardt, Aviral Singh, Maythinee Chantadisai, Franz C. Robiller, Jingjing Zhang, Dirk Mueller, Alexander Eismant, Frankis Almaguel, Dirk Zboralski, Frank Osterkamp, Aileen Hoehne, Ulrich Reineke, Christiane Smerling and Harshad R. Kulkarni
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 415-423; DOI: https://doi.org/10.2967/jnumed.120.259192
Basic
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  A Radiotracer for Molecular Imaging and Therapy of Gastrin-Releasing Peptide Receptor–Positive Prostate Cancer
  Ivica J. Bratanovic, Chengcheng Zhang, Zhengxing Zhang, Hsiou‐Ting Kuo, Nadine Colpo, Jutta Zeisler, Helen Merkens, Carlos Uribe, Kuo‐Shyan Lin and François Bénard
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 424-430; DOI: https://doi.org/10.2967/jnumed.120.257758

Cardiovascular

Clinical
- Open Access
  Sex Differences and Caffeine Impact in Adenosine-Induced Hyperemia
  Martin Lyngby Lassen, Christina Byrne, Majid Sheykhzade, Mads Wissenberg, Preetee Kapisha Hurry, Anne Vibeke Schmedes, Andreas Kjaer and Philip Hasbak
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 431-437; DOI: https://doi.org/10.2967/jnumed.121.261970

Neurology

Clinical
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  Striatal Acetylcholine–Dopamine Imbalance in Parkinson Disease: In Vivo Neuroimaging Study with Dual-Tracer PET and Dopaminergic PET–Informed Correlational Tractography
  Carlos A. Sanchez-Catasus, Nicolaas I. Bohnen, Nicholas D’Cruz and Martijn L.T.M. Müller
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 438-445; DOI: https://doi.org/10.2967/jnumed.121.261939
Basic
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    A Longitudinal PET/MRI Study of Colony-Stimulating Factor 1 Receptor–Mediated Microglia Depletion in Experimental Stroke
    Cristina Barca, Amanda J. Kiliaan, Claudia Foray, Lydia Wachsmuth, Sven Hermann, Cornelius Faber, Michael Schäfers, Maximilian Wiesmann, Andreas H. Jacobs and Bastian Zinnhardt
    
    Journal of Nuclear Medicine March 1, 2022, 63 (3) 446-452; DOI: https://doi.org/10.2967/jnumed.121.262279

Infectious Disease

Clinical
- Open Access
  Lessons Learned from Post–COVID-19 Vaccination PET/CT Studies
  Marina Orevi, Alexandre Chicheportiche and Simona Ben Haim
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 453-460; DOI: https://doi.org/10.2967/jnumed.121.262348

Molecular Imaging

Basic
- Open Access
  PET Tracing of Biodistribution for Orally Administered ⁶⁴Cu-Labeled Polystyrene in Mice
  Changkeun Im, Hyeongi Kim, Javeria Zaheer, Jung Young Kim, Yong-Jin Lee, Choong Mo Kang and Jin Su Kim
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 461-467; DOI: https://doi.org/10.2967/jnumed.120.256982

AI/Advanced Image Analysis

Clinical
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  Evaluation of Deep Learning–Based Approaches to Segment Bowel Air Pockets and Generate Pelvic Attenuation Maps from CAIPIRINHA-Accelerated Dixon MR Images
  Hasan Sari, Ja Reaungamornrat, Onofrio A. Catalano, Javier Vera-Olmos, David Izquierdo-Garcia, Manuel A. Morales, Angel Torrado-Carvajal, Thomas S.C. Ng, Norberto Malpica, Ali Kamen and Ciprian Catana
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 468-475; DOI: https://doi.org/10.2967/jnumed.120.261032

Physics and Instrumentation

Basic
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  Performance Characteristics of the Biograph Vision Quadra PET/CT System with a Long Axial Field of View Using the NEMA NU 2-2018 Standard
  George A. Prenosil, Hasan Sari, Markus Fürstner, Ali Afshar-Oromieh, Kuangyu Shi, Axel Rominger and Michael Hentschel
  
  Journal of Nuclear Medicine March 1, 2022, 63 (3) 476-484; DOI: https://doi.org/10.2967/jnumed.121.261972

Special Contribution

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RADAR Guide: Standard Methods for Calculating Radiation Doses for Radiopharmaceuticals, Part 2—Data Analysis and Dosimetry
Michael G. Stabin, Richard E. Wendt and Glenn D. Flux

Journal of Nuclear Medicine March 1, 2022, 63 (3) 485-492; DOI: https://doi.org/10.2967/jnumed.121.262034

Letters To The Editor

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⁶⁸Ga-NODAGA-Exendin-4 PET Scanning for Focal Congenital Hyperinsulinism: Need for Replication
Indraneel Banerjee, Rakesh Sajjan, Maria Salomon Estebanez, Mark J. Dunne, Konrad Mohnike, Wolfgang Mohnike, Lisa J. States, Diva D. De Leon and Klaus Mohnike

Journal of Nuclear Medicine March 1, 2022, 63 (3) 493; DOI: https://doi.org/10.2967/jnumed.121.262984
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Reply: ⁶⁸Ga NODAGA-Exendin-4 PET Scanning for Focal Congenital Hyperinsulinism: Need for Replication
Vikas Prasad, Marti Boss, Christof Rottenburger, Winfried Brenner, Oliver Blankenstein, Sonal Prasad, Mijke Buitinga, Pratik Shah and Martin Gotthardt

Journal of Nuclear Medicine March 1, 2022, 63 (3) 493-494; DOI: https://doi.org/10.2967/jnumed.121.263167
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Adding Nontumor Radiomic Features to the Prognostic Model Is Bothersome but Useful
Lu Zhang and Bin Zhang

Journal of Nuclear Medicine March 1, 2022, 63 (3) 494-495; DOI: https://doi.org/10.2967/jnumed.121.263479
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Reply: Adding Nontumor Radiomic Features to the Prognostic Model Is Bothersome but Useful
Tahir I. Yusufaly and Loren K. Mell

Journal of Nuclear Medicine March 1, 2022, 63 (3) 495; DOI: https://doi.org/10.2967/jnumed.121.263730

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine March 1, 2022, 63 (3) 11N-22N;
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SNMMI Statement: Possible Effect of Omicron Infection on ¹⁸F-FDG–Based Imaging
Journal of Nuclear Medicine March 1, 2022, 63 (3) 11N;
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CMS Proposes Medicare Coverage Policy for Monoclonal Antibody–Based Alzheimer Treatment
Journal of Nuclear Medicine March 1, 2022, 63 (3) 12N;
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SNMMI Reacts to CMS Coverage Decision
Journal of Nuclear Medicine March 1, 2022, 63 (3) 12N;
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HFR Outage and Isotope Supply
Journal of Nuclear Medicine March 1, 2022, 63 (3) 13N;
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FDA Guidance on Patient Engagement in Medical Device Clinical Studies
Journal of Nuclear Medicine March 1, 2022, 63 (3) 13N;
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SNMMI Launches Radiopharmaceutical Therapy Centers of Excellence Program
Journal of Nuclear Medicine March 1, 2022, 63 (3) 14N;
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SNMMI Leadership Update: Call the Nuclear Oncologist
Richard L. Wahl

Journal of Nuclear Medicine March 1, 2022, 63 (3) 15N;
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Newsbriefs
Journal of Nuclear Medicine March 1, 2022, 63 (3) 16N-17N;
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From the Literature
Journal of Nuclear Medicine March 1, 2022, 63 (3) 18N-22N;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of The Art

Hot Topics

Continuing Education

Focus on Molecular Imaging

Oncology

Clinical

INVITED PERSPECTIVE

BRIEF COMMUNICATION

Theranostics

Clinical

BRIEF COMMUNICATION

BRIEF COMMUNICATION

BRIEF COMMUNICATION

FEATURED ARTICLE OF THE MONTH

Basic

Cardiovascular

Clinical

Neurology

Clinical

Basic

FEATURED BASIC SCIENCE ARTICLE

Infectious Disease

Clinical

Molecular Imaging

Basic

AI/Advanced Image Analysis

Clinical

Physics and Instrumentation

Basic

Special Contribution

Letters To The Editor

SNMMI Newsline

In this issue

Issue highlights

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