Journal of Nuclear Medicine: 63 (12)

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December 1, 2022; Volume 63,Issue 12

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine December 1, 2022, 63 (12) 12A;

Discussions with Leaders

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Leading in Urology and Pioneering in Social Media Outreach
Declan Murphy, Ken Herrmann and Michael Hofman

Journal of Nuclear Medicine December 1, 2022, 63 (12) 1783-1785; DOI: https://doi.org/10.2967/jnumed.122.265028

The State of the Art

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Fibroblast Activation Protein Inhibitor Imaging in Nonmalignant Diseases: A New Perspective for Molecular Imaging
Christian Schmidkonz, Torsten Kuwert, Armin Atzinger, Michael Cordes, Georg Schett, Andreas Ramming and Theresa Götz

Journal of Nuclear Medicine December 1, 2022, 63 (12) 1786-1792; DOI: https://doi.org/10.2967/jnumed.122.264205

Continuing Education

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From Concept to Regulatory Drug Approval: Lessons for Theranostics
Marlon Perera and Michael J. Morris

Journal of Nuclear Medicine December 1, 2022, 63 (12) 1793-1801; DOI: https://doi.org/10.2967/jnumed.121.263301

Focus on Molecular Imaging

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Nanoparticle Diagnostics and Theranostics in the Clinic
Roger M. Pallares, Felix M. Mottaghy, Volkmar Schulz, Fabian Kiessling and Twan Lammers

Journal of Nuclear Medicine December 1, 2022, 63 (12) 1802-1808; DOI: https://doi.org/10.2967/jnumed.122.263895

Theranostics

Clinical
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  Validation of ¹⁸F-rhPSMA-7 and ¹⁸F-rhPSMA-7.3 PET Imaging Results with Histopathology from Salvage Surgery in Patients with Biochemical Recurrence of Prostate Cancer
  Markus Kroenke, Lilit Schweiger, Thomas Horn, Bernhard Haller, Kristina Schwamborn, Alexander Wurzer, Tobias Maurer, Hans-Jürgen Wester, Matthias Eiber and Isabel Rauscher
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1809-1814; DOI: https://doi.org/10.2967/jnumed.121.263707
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  Using ⁶⁸Ga-PSMA-11 PET/CT for Therapy Response Assessment in Patients with Metastatic Castration-Resistant Prostate Cancer: Application of EAU/EANM Recommendations in Clinical Practice
  Chloé S. Denis, François Cousin, Bram De Laere, Roland Hustinx, Brieuc R. Sautois and Nadia Withofs
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1815-1821; DOI: https://doi.org/10.2967/jnumed.121.263611
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  ⁶⁸Ga-PSMA-11 PET/MRI in Patients with Newly Diagnosed Intermediate- or High-Risk Prostate Adenocarcinoma: PET Findings Correlate with Outcomes After Definitive Treatment
  Farshad Moradi, Heying Duan, Hong Song, Guido A. Davidzon, Benjamin I. Chung, Alan E. C. Thong, Andreas M. Loening, Pejman Ghanouni, Geoffrey Sonn and Andrei Iagaru
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1822-1828; DOI: https://doi.org/10.2967/jnumed.122.263897
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  Correlation of ⁶⁸Ga-RM2 PET with Postsurgery Histopathology Findings in Patients with Newly Diagnosed Intermediate- or High-Risk Prostate Cancer
  Heying Duan, Lucia Baratto, Richard E. Fan, Simon John Christoph Soerensen, Tie Liang, Benjamin Inbeh Chung, Alan Eih Chih Thong, Harcharan Gill, Christian Kunder, Tanya Stoyanova, Mirabela Rusu, Andreas M. Loening, Pejman Ghanouni, Guido A. Davidzon, Farshad Moradi, Geoffrey A. Sonn and Andrei Iagaru
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1829-1835; DOI: https://doi.org/10.2967/jnumed.122.263971
- SPECIAL CONTRIBUTION
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    Joint EANM, SNMMI, and IAEA Enabling Guide: How to Set up a Theranostics Center
    Ken Herrmann, Luca Giovanella, Andrea Santos, Jonathan Gear, Pinar Ozgen Kiratli, Jens Kurth, Ana M. Denis-Bacelar, Roland Hustinx, Marianne Patt, Richard L. Wahl, Diana Paez, Francesco Giammarile, Hossein Jadvar, Neeta Pandit-Taskar, Munir Ghesani and Jolanta Kunikowska
    
    Journal of Nuclear Medicine December 1, 2022, 63 (12) 1836-1843; DOI: https://doi.org/10.2967/jnumed.122.264321
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  Repetitive Early ⁶⁸Ga-FAPI PET Acquisition Comparing ⁶⁸Ga-FAPI-02, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-FAPI-74: Methodologic and Diagnostic Implications for Malignant, Inflammatory/Reactive, and Degenerative Lesions
  Frederik M. Glatting, Jorge Hoppner, Dawn P. Liew, Antonia van Genabith, Anna-Maria Spektor, Levin Steinbach, Alexander Hubert, Clemens Kratochwil, Frederik L. Giesel, Katharina Dendl, Hendrik Rathke, Hans-Ulrich Kauczor, Peter E. Huber, Uwe Haberkorn and Manuel Röhrich
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1844-1851; DOI: https://doi.org/10.2967/jnumed.122.264069
Basic
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  A Dimeric FAP-Targeting Small-Molecule Radioconjugate with High and Prolonged Tumor Uptake
  Andrea Galbiati, Aureliano Zana, Matilde Bocci, Jacopo Millul, Abdullah Elsayed, Jacqueline Mock, Dario Neri and Samuele Cazzamalli
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1852-1858; DOI: https://doi.org/10.2967/jnumed.122.264036
- FEATURED ARTICLE OF THE MONTH
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    Improved Tumor Responses with Sequential Targeted α-Particles Followed by Interleukin 2 Immunocytokine Therapies in Treatment of CEA-Positive Breast and Colon Tumors in CEA Transgenic Mice
    Megan Minnix, Maciej Kujawski, Erasmus Poku, Paul J. Yazaki, Jeffrey Y. Wong and John E. Shively
    
    Journal of Nuclear Medicine December 1, 2022, 63 (12) 1859-1864; DOI: https://doi.org/10.2967/jnumed.122.264126

Oncology

Clinical
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  ¹⁸F-DOPA PET/CT at the Forefront of Initial or Presurgical Evaluation of Small-Intestine Neuroendocrine Tumors
  Eric Ouvrard, Louis De Mestier, Caroline Boursier, Boumediene Lachachi, Nicolas Sahakian, Elodie Chevalier, Nidaa Mikail, Josefina Carullo, Aurélie Bando-Delaunay, Thomas Walter, Gabriel G. Malouf, Pietro Addeo, Gilles Poncet, Frederic Sebag, Rachida Lebtahi, Bernard Goichot, David Taïeb and Alessio Imperiale
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1865-1870; DOI: https://doi.org/10.2967/jnumed.122.263984
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  First-in-Humans PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using ¹⁸F-labeled Active-Site Inhibited Factor VII (¹⁸F-ASIS): Potential as Companion Diagnostic
  Mathias Loft, Camilla Christensen, Malene M. Clausen, Esben A. Carlsen, Carsten P. Hansen, Niels Kroman, Seppo W. Langer, Claus Høgdall, Jacob Madsen, Nic Gillings, Carsten H. Nielsen, Thomas L. Klausen, Søren Holm, Annika Loft, Anne K. Berthelsen and Andreas Kjaer
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1871-1879; DOI: https://doi.org/10.2967/jnumed.122.264068
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  ⁸⁹Zr-Labeled High-Density Lipoprotein Nanoparticle PET Imaging Reveals Tumor Uptake in Patients with Esophageal Cancer
  Kang H. Zheng, Jeffrey Kroon, Jasper Schoormans, Oliver Gurney-Champion, Sybren L. Meijer, Suzanne S. Gisbertz, Maarten C.C.M. Hulshof, Danielle J. Vugts, Guus A.M.S. van Dongen, Bram F. Coolen, Hein J. Verberne, Aart J. Nederveen, Erik S.G. Stroes and Hanneke W.M. van Laarhoven
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1880-1886; DOI: https://doi.org/10.2967/jnumed.121.263330
- BRIEF COMMUNICATION
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    ¹⁸F-FDG PET/CT Staging of Head and Neck Cancer: Interobserver Agreement and Accuracy—Results from Multicenter ACRIN 6685 Clinical Trial
    Rathan M. Subramaniam, Fenghai M. Duan, Justin Romanoff, Jian Qin Yu, Twyla Bartel, Farrokh Dehdashti, Charles M. Intenzo, Lilja Solnes, JoRean Sicks, Brendan C. Stack and Val J. Lowe
    
    Journal of Nuclear Medicine December 1, 2022, 63 (12) 1887-1890; DOI: https://doi.org/10.2967/jnumed.122.263902
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  Safety and Efficacy of ¹⁶⁶Ho Radioembolization in Hepatocellular Carcinoma: The HEPAR Primary Study
  Margot T.M. Reinders, Karel J. van Erpecum, Maarten L.J. Smits, Arthur J.A.T. Braat, Joep de Bruijne, Rutger Bruijnen, Dave Sprengers, Robert A. de Man, Erik Vegt, Jan N.M. IJzermans, Adriaan Moelker and Marnix G.E.H. Lam
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1891-1898; DOI: https://doi.org/10.2967/jnumed.122.263823
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  Noninvasive Assessment of Acute Graft-Versus-Host Disease of the Gastrointestinal Tract After Allogeneic Hemopoietic Stem Cell Transplantation Using ¹⁸F-FDG PET
  Martin H. Cherk, Robert Khor, Thomas W. Barber, Kenneth S.K. Yap, Sushrut Patil, Patricia Walker, Sharon Avery, Stuart Roberts, William Kemp, Alan Pham, Michael Bailey and Victor Kalff
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1899-1905; DOI: https://doi.org/10.2967/jnumed.121.263688

Cardiovascular

Clinical
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    Prevalence and Outcomes of Cardiac Amyloidosis in All-Comer Referrals for Bone Scintigraphy
    Christian Nitsche, Katharina Mascherbauer, Raffaella Calabretta, Matthias Koschutnik, Carolina Dona, Varius Dannenberg, Felix Hofer, Kseniya Halavina, Andreas A. Kammerlander, Tatjana Traub-Weidinger, Georg Goliasch, Christian Hengstenberg, Marcus Hacker and Julia Mascherbauer
    
    Journal of Nuclear Medicine December 1, 2022, 63 (12) 1906-1911; DOI: https://doi.org/10.2967/jnumed.122.264041

Neurology

Basic
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  Evaluation of (rac)-, (R)-, and (S)-¹⁸F-OF-NB1 for Imaging GluN2B Subunit–Containing N-Methyl-d-Aspartate Receptors in Nonhuman Primates
  Hazem Ahmed, Ming-Qiang Zheng, Kelly Smart, Hanyi Fang, Li Zhang, Paul R. Emery, Hong Gao, Jim Ropchan, Ahmed Haider, Gilles Tamagnan, Richard E. Carson, Simon M. Ametamey and Yiyun Huang
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1912-1918; DOI: https://doi.org/10.2967/jnumed.122.263977
Translational
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  First-in-Human Evaluation of ¹⁸F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
  Yuichi Wakabayashi, Per Stenkrona, Ryosuke Arakawa, Xuefeng Yan, Maia G. Van Buskirk, Madeline D. Jenkins, Jose A. Montero Santamaria, Kevin P. Maresca, Akihiro Takano, Jeih-San Liow, Thomas A. Chappie, Andrea Varrone, Sangram Nag, Lei Zhang, Zoë A. Hughes, Christopher J. Schmidt, Shawn D. Doran, Andrew Mannes, Paolo Zanotti-Fregonara, Maarten Ooms, Cheryl L. Morse, Sami S. Zoghbi, Christer Halldin, Victor W. Pike and Robert B. Innis
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1919-1924; DOI: https://doi.org/10.2967/jnumed.122.263838

AI/Advanced Image Analysis

Clinical
- Open Access
  ¹⁸F-FDG PET Maximum-Intensity Projections and Artificial Intelligence: A Win-Win Combination to Easily Measure Prognostic Biomarkers in DLBCL Patients
  Kibrom B. Girum, Louis Rebaud, Anne-Ségolène Cottereau, Michel Meignan, Jérôme Clerc, Laetitia Vercellino, Olivier Casasnovas, Franck Morschhauser, Catherine Thieblemont and Irène Buvat
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1925-1932; DOI: https://doi.org/10.2967/jnumed.121.263501
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  Distinction of Lymphoma from Sarcoidosis on ¹⁸F-FDG PET/CT: Evaluation of Radiomics-Feature–Guided Machine Learning Versus Human Reader Performance
  Pierre Lovinfosse, Marta Ferreira, Nadia Withofs, Alexandre Jadoul, Céline Derwael, Anne-Noelle Frix, Julien Guiot, Claire Bernard, Anh Nguyet Diep, Anne-Françoise Donneau, Marie Lejeune, Christophe Bonnet, Wim Vos, Patrick E. Meyer and Roland Hustinx
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1933-1940; DOI: https://doi.org/10.2967/jnumed.121.263598
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  Fully Automated, Semantic Segmentation of Whole-Body ¹⁸F-FDG PET/CT Images Based on Data-Centric Artificial Intelligence
  Lalith Kumar Shiyam Sundar, Josef Yu, Otto Muzik, Oana C. Kulterer, Barbara Fueger, Daria Kifjak, Thomas Nakuz, Hyung Min Shin, Annika Katharina Sima, Daniela Kitzmantl, Ramsey D. Badawi, Lorenzo Nardo, Simon R. Cherry, Benjamin A. Spencer, Marcus Hacker and Thomas Beyer
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1941-1948; DOI: https://doi.org/10.2967/jnumed.122.264063

Endocrinology

Translational
- Open Access
  Development of Fluorinated NP-59: A Revival of Cholesterol Use Imaging with PET
  Allen F. Brooks, Wade P. Winton, Jenelle Stauff, Janna Arteaga, Bradford Henderson, Jeremy Niedbala, Peter J.H. Scott and Benjamin L. Viglianti
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1949-1955; DOI: https://doi.org/10.2967/jnumed.122.263864

Gastroenterology

Basic
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  Staging Liver Fibrosis by Fibroblast Activation Protein Inhibitor PET in a Human-Sized Swine Model
  Ali Pirasteh, Sarvesh Periyasamy, Jennifer Jean Meudt, Yongjun Liu, Laura M. Lee, Kyle M. Schachtschneider, Lawrence B. Schook, Ron C. Gaba, Lu Mao, Adnan Said, Alan Blair McMillan, Paul F. Laeseke and Dhanansayan Shanmuganayagam
  
  Journal of Nuclear Medicine December 1, 2022, 63 (12) 1956-1961; DOI: https://doi.org/10.2967/jnumed.121.263736

Illustrated Post

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A Long Axial Field of View Enables PET/CT in Toddler Without Sedation
Michala Reichkendler, Flemming L. Andersen, Lise Borgwardt, Ulrikka Nygaard, Elisabeth Albrecht-Beste, Kim F. Andersen, Anna Ljunggren, Nynne Abrahamsen, Annika Loft, Liselotte Højgaard and Barbara M. Fischer

Journal of Nuclear Medicine December 1, 2022, 63 (12) 1962; DOI: https://doi.org/10.2967/jnumed.121.263626

Departments

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Recruitment
Journal of Nuclear Medicine December 1, 2022, 63 (12) 10A;

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine December 1, 2022, 63 (12) 13N-24N;
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2022 SNMMI Highlights Lecture: Oncology and Therapy, Part 1
Heiko Schöder

Journal of Nuclear Medicine December 1, 2022, 63 (12) 13N-18N;
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SNMMI Adopts New Strategic Plan
Munir Ghesani

Journal of Nuclear Medicine December 1, 2022, 63 (12) 19N-20N;
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NewsBriefs
Journal of Nuclear Medicine December 1, 2022, 63 (12) 21N;
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From the Literature
Journal of Nuclear Medicine December 1, 2022, 63 (12) 22N-24N;

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This Month in JNM

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Continuing Education

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Theranostics

Clinical

SPECIAL CONTRIBUTION

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FEATURED ARTICLE OF THE MONTH

Oncology

Clinical

BRIEF COMMUNICATION

Cardiovascular

Clinical

FEATURED CLINICAL INVESTIGATION ARTICLE

Neurology

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Translational

AI/Advanced Image Analysis

Clinical

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