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(R)-18F-OF-Me-NB1 n=1 (R)-11C-NR2B-Me n=2 (S)-18F-OF-NB1 n=2 fP 1.2% 0.7% 15% Baseline VT range (mL/cm3) 8.2-12.8 23.5-54.6 16.9-38.8 VND (mL/cm3) 6.4 11.2 8.3 Mean cortical BPND 0.65 2.64 2.53 GluN2B blocking Co-101,244 (0.25 mg/kg) 77% 95% 85% σ1 blocking FTC-146 (0.027 mg/kg) 30% 49% FTC-146 (0.125 mg/kg) 56% 48%
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