Journal of Nuclear Medicine: 62 (8)

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August 1, 2021; Volume 62,Issue 8

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine August 1, 2021, 62 (8) 10A;

Editor's Page

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¹⁷⁷Lu-PSMA617 and the VISION Trial: One of the Greatest Success Stories in the History of Nuclear Medicine
Johannes Czernin and Jeremie Calais

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1025-1026; DOI: https://doi.org/10.2967/jnumed.121.262710

Discussions with Leaders

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Perspectives on Cutting-Edge Clinical Trials
Michael S. Hofman, Jérémie Calais and Johannes Czernin

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1027-1030; DOI: https://doi.org/10.2967/jnumed.121.262681

Hot Topics

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Landscape Analysis of Phase 2 and 3 Clinical Trials for Targeted Radionuclide Therapy
Erik Mittra and Lisa Bodei

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1031-1032; DOI: https://doi.org/10.2967/jnumed.120.258103

Continuing Education

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Imaging of Pheochromocytoma and Paraganglioma
Jorge A. Carrasquillo, Clara C. Chen, Abhishek Jha, Alexander Ling, Frank I. Lin, Daniel A. Pryma and Karel Pacak

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1033-1042; DOI: https://doi.org/10.2967/jnumed.120.259689

Focus on Molecular Imaging

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Repurposing ^99mTc-Mebrofenin as a Probe for Molecular Imaging of Hepatocyte Transporters
Solène Marie, Irene Hernández-Lozano, Oliver Langer and Nicolas Tournier

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1043-1047; DOI: https://doi.org/10.2967/jnumed.120.261321

Editorial

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At Last, ¹⁸F-FDG for Inflammation and Infection!
Richard L. Wahl, Vasken Dilsizian and Christopher J. Palestro

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1048-1049; DOI: https://doi.org/10.2967/jnumed.121.262446

Oncology

Clinical
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  Quantification of Metastatic Prostate Cancer Whole-Body Tumor Burden with ¹⁸F-FDG PET Parameters and Associations with Overall Survival After First-Line Abiraterone or Enzalutamide: A Single-Center Retrospective Cohort Study
  Andreas G. Wibmer, Michael J. Morris, Mithat Gonen, Junting Zheng, Hedvig Hricak, Steven Larson, Howard I. Scher and Hebert Alberto Vargas
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1050-1056; DOI: https://doi.org/10.2967/jnumed.120.256602
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  PET/CT-Guided Biopsy of Suspected Lung Lesions Requires Less Rebiopsy Than CT-Guided Biopsy Due to Inconclusive Results
  Juliano J. Cerci, Mateos Bogoni, Rodrigo J. Cerci, Margaret Masukawa, Carlos C.P. Neto, Cassiano Krauzer, Stefano Fanti, Danielle G. Sakamoto, Renan B. Barreiros, Cristina Nanni and João V Vitola
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1057-1061; DOI: https://doi.org/10.2967/jnumed.120.252403
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  Lymph Node Staging with a Combined Protocol of ¹⁸F-FDG PET/MRI and Sentinel Node SPECT/CT: A Prospective Study in Patients with FIGO I/II Cervical Carcinoma
  Matthias Weissinger, Florin-Andrei Taran, Sergios Gatidis, Stefan Kommoss, Konstantin Nikolaou, Samine Sahbai, Christian la Fougère, Sara Yvonne Brucker and Helmut Dittmann
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1062-1067; DOI: https://doi.org/10.2967/jnumed.120.255919
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  Interim PET in Diffuse Large B-Cell Lymphoma
  Lars Kurch, Andreas Hüttmann, Thomas W. Georgi, Jan Rekowski, Osama Sabri, Christine Schmitz, Regine Kluge, Ulrich Dührsen and Dirk Hasenclever
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1068-1074; DOI: https://doi.org/10.2967/jnumed.120.255034

Theranostics

Clinical
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  Radiation Dosimetry of ^99mTc-PSMA I&S: A Single-Center Prospective Study
  Szabolcs Urbán, Catherine Meyer, Magnus Dahlbom, István Farkas, Gábor Sipka, Zsuzsanna Besenyi, Johannes Czernin, Jeremie Calais and László Pávics
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1075-1081; DOI: https://doi.org/10.2967/jnumed.120.253476
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  Matched-Pair Comparison of ⁶⁸Ga-PSMA-11 and ¹⁸F-rhPSMA-7 PET/CT in Patients with Primary and Biochemical Recurrence of Prostate Cancer: Frequency of Non–Tumor-Related Uptake and Tumor Positivity
  Markus Kroenke, Lilit Mirzoyan, Thomas Horn, Jan C. Peeken, Alexander Wurzer, Hans-Jürgen Wester, Marcus Makowski, Wolfgang A. Weber, Matthias Eiber and Isabel Rauscher
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1082-1088; DOI: https://doi.org/10.2967/jnumed.120.251447
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    Salvage Radiotherapy Management Decisions in Postprostatectomy Patients with Recurrent Prostate Cancer Based on ¹⁸F-Fluciclovine PET/CT Guidance
    Olayinka A. Abiodun-Ojo, Ashesh B. Jani, Akinyemi A. Akintayo, Oladunni O. Akin-Akintayo, Oluwaseun A. Odewole, Funmilayo I. Tade, Shreyas S. Joshi, Viraj A. Master, Bridget Fielder, Raghuveer K. Halkar, Chao Zhang, Subir Goyal, Mark M. Goodman and David M. Schuster
    
    Journal of Nuclear Medicine August 1, 2021, 62 (8) 1089-1096; DOI: https://doi.org/10.2967/jnumed.120.256784
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  Phase I Trial of ¹³¹I-GMIB-Anti-HER2-VHH1, a New Promising Candidate for HER2-Targeted Radionuclide Therapy in Breast Cancer Patients
  Matthias D’Huyvetter, Jens De Vos, Vicky Caveliers, Ilse Vaneycken, Johannes Heemskerk, Francois P. Duhoux, Christel Fontaine, Marian Vanhoeij, Albert D. Windhorst, Frank van der Aa, N. Harry Hendrikse, Jos L.E. Eersels, Hendrik Everaert, Pieterjan Gykiere, Nick Devoogdt, Geert Raes, Tony Lahoutte and Marleen Keyaerts
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1097-1105; DOI: https://doi.org/10.2967/jnumed.120.255679
Basic
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  Comparative Preclinical Biodistribution, Dosimetry, and Endoradiotherapy in Metastatic Castration-Resistant Prostate Cancer Using ¹⁹F/¹⁷⁷Lu-rhPSMA-7.3 and ¹⁷⁷Lu-PSMA I&T
  Nahid Yusufi, Alexander Wurzer, Michael Herz, Calogero D’Alessandria, Benedikt Feuerecker, Wolfgang Weber, Hans-Jürgen Wester, Stephan Nekolla and Matthias Eiber
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1106-1111; DOI: https://doi.org/10.2967/jnumed.120.254516

Cardiovascular

Clinical
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  Simulation of Low-Dose Protocols for Myocardial Perfusion ⁸²Rb Imaging
  Martin Lyngby Lassen, Yuka Otaki, Paul Kavanagh, Robert J.H. Miller, Daniel S. Berman and Piotr J. Slomka
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1112-1117; DOI: https://doi.org/10.2967/jnumed.120.252429

Radiobiology/Dosimetry

Clinical
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  A Novel Time–Activity Information-Sharing Approach Using Nonlinear Mixed Models for Patient-Specific Dosimetry with Reduced Imaging Time Points: Application in SPECT/CT After ¹⁷⁷Lu-DOTATATE
  Theresa P. Devasia, Yuni K. Dewaraja, Kirk A. Frey, Ka Kit Wong and Matthew J. Schipper
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1118-1125; DOI: https://doi.org/10.2967/jnumed.120.256255
- Open Access
  Evaluation of Safety and Dosimetry of ¹⁷⁷Lu-DOTA-ZOL for Therapy of Bone Metastases
  René Fernández, Elisabeth Eppard, Wencke Lehnert, Luis David Jiménez-Franco, Cristian Soza-Ried, Matías Ceballos, Jessica Ribbeck, Andreas Kluge, Frank Rösch, Marian Meckel, Konstantin Zhernosekov, Vasko Kramer and Horacio Amaral
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1126-1132; DOI: https://doi.org/10.2967/jnumed.120.255851
- SPECIAL CONTRIBUTIOIN
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    Overview of the First NRG Oncology–National Cancer Institute Workshop on Dosimetry of Systemic Radiopharmaceutical Therapy
    Emilie Roncali, Jacek Capala, Stanley H. Benedict, Gamal Akabani, Bryan Bednarz, Vikram Bhadrasain, Wesley E. Bolch, Jeffrey C. Buchsbaum, Norman C. Coleman, Yuni K. Dewaraja, Eric Frey, Michael Ghaly, Joseph Grudzinski, Robert F. Hobbs, Roger W. Howell, John L. Humm, Charles A. Kunos, Steve Larson, Frank I. Lin, Mark Madsen, Saed Mirzadeh, David Morse, Daniel Pryma, George Sgouros, Sara St. James, Richard L. Wahl, Ying Xiao, Pat Zanzonico and Katherine Zukotynski
    
    Journal of Nuclear Medicine August 1, 2021, 62 (8) 1133-1139; DOI: https://doi.org/10.2967/jnumed.120.255547

Molecular Imaging

Basic
- FEATURED ARTICLE OF THE MONTH
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    Synthesis and Evaluation of ¹⁸F-Enzalutamide, a New Radioligand for PET Imaging of Androgen Receptors: A Comparison with 16β-¹⁸F-Fluoro-5α-Dihydrotestosterone
    Inês F. Antunes, Rutger J. Dost, Hilde D. Hoving, Aren van Waarde, Rudi A.J.O Dierckx, Douwe F. Samplonius, Wijnand Helfrich, Philip H. Elsinga, Erik F.J. de Vries and Igle J. de Jong
    
    Journal of Nuclear Medicine August 1, 2021, 62 (8) 1140-1145; DOI: https://doi.org/10.2967/jnumed.120.253641
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  Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI
  Chao Wang, Benjamin I. Leach, Deanne Lister, Stephen R. Adams, Hongyan Xu, Carl Hoh, Patrick McConville, Jing Zhang, Karen Messer and Eric T. Ahrens
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1146-1153; DOI: https://doi.org/10.2967/jnumed.120.255273
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  Kinetic Modeling of ¹⁸F-(2S,4R)4-Fluoroglutamine in Mouse Models of Breast Cancer to Estimate Glutamine Pool Size as an Indicator of Tumor Glutamine Metabolism
  Varsha Viswanath, Rong Zhou, Hsiaoju Lee, Shihong Li, Abigail Cragin, Robert K. Doot, David A. Mankoff and Austin R. Pantel
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1154-1162; DOI: https://doi.org/10.2967/jnumed.120.250977

Radiochemistry

Basic
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  Mapping Arginase Expression with ¹⁸F-Fluorinated Late-Generation Arginase Inhibitors Derived from Quaternary α-Amino Acids
  Gonçalo S. Clemente, Inês F. Antunes, Santosh Kurhade, Mariska P.M. van den Berg, Jürgen W.A. Sijbesma, Aren van Waarde, Rogier C. Buijsman, Nicole Willemsen-Seegers, Reinoud Gosens, Herman Meurs, Alexander Dömling and Philip H. Elsinga
  
  Journal of Nuclear Medicine August 1, 2021, 62 (8) 1163-1170; DOI: https://doi.org/10.2967/jnumed.120.255968

Challenging Case Studies

Open Access
Postinfectious Neurologic Complications in COVID-19: A Complex Case Report
Pietro Tiraboschi, Rubjona Xhani, Simone M. Zerbi, Angelo Corso, Isabella Martinelli, Laura Fusi, Giampiero Grampa, Andrea Lombardo, Paola Cavalcante, Cristina Cappelletti, Francesca Andreetta, Alberto Sironi, Alberto Redolfi and Cristina Muscio

Journal of Nuclear Medicine August 1, 2021, 62 (8) 1171-1176; DOI: https://doi.org/10.2967/jnumed.120.256099

Errata

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Errata
Journal of Nuclear Medicine August 1, 2021, 62 (8) 1176;

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine August 1, 2021, 62 (8) 11N-22N;
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FDA Approves ¹⁸F-DCFPyL PET Agent in Prostate Cancer
Journal of Nuclear Medicine August 1, 2021, 62 (8) 11N;
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2021 SNMMI Highlights Lecture: General Nuclear Medicine
Andrei Iagaru

Journal of Nuclear Medicine August 1, 2021, 62 (8) 12N-17N;
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Larson Recognized with 2021 Paul C. Aebersold Award
Journal of Nuclear Medicine August 1, 2021, 62 (8) 18N-19N;
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Ruth Receives SNMMI Georg Charles de Hevesy Nuclear Pioneer Award
Thomas J. Ruth

Journal of Nuclear Medicine August 1, 2021, 62 (8) 19N;
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SNMMI Honors Contributors at 2021 Annual Meeting
Journal of Nuclear Medicine August 1, 2021, 62 (8) 20N-21N;
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The SNMMI 2021 Virtual Annual Meeting: Accessible, Exceptional Research and Education
Virginia Pappas

Journal of Nuclear Medicine August 1, 2021, 62 (8) 22N;

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FEATURED CLINICAL INVESTIGATION ARTICLE

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Clinical

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Molecular Imaging

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FEATURED ARTICLE OF THE MONTH

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