Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Permissions
    • Advertisers
    • Continuing Education
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Editorial Contact
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Permissions
    • Advertisers
    • Continuing Education
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Editorial Contact
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • Follow SNMMI on Twitter
  • Visit SNMMI on Facebook
Research ArticlePhysics and Instrumentation

Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications

Matthew G. Spangler-Bickell, Timothy W. Deller, Valentino Bettinardi and Floris Jansen
Journal of Nuclear Medicine February 2021, 62 (2) 287-292; DOI: https://doi.org/10.2967/jnumed.120.245597
Matthew G. Spangler-Bickell
1Department of Radiology, University of Wisconsin, Madison, Wisconsin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Timothy W. Deller
2PET/MR Engineering, GE Healthcare, Waukesha, Wisconsin; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Valentino Bettinardi
3Nuclear Medicine Unit, IRCCS Ospedale San Raffaele, Milan, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Floris Jansen
2PET/MR Engineering, GE Healthcare, Waukesha, Wisconsin; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF
Loading

Visual Abstract

Figure1
  • Download figure
  • Open in new tab
  • Download powerpoint

Abstract

Standard clinical reconstructions usually require several minutes to complete, and this time is mostly independent of the duration of the data being reconstructed. Applications such as data-driven motion estimation, which require many short frames over the duration of the scan, become unfeasible with such long reconstruction times. In this work, we present an infrastructure whereby ultra-fast list-mode reconstructions of very short frames (≤1 s) are performed. With this infrastructure, it is possible to have a dynamic series of frames that can be used for various applications, such as data-driven motion estimation, whole-body surveys, quick reconstructions of gated data to select the optimal gate for a given attenuation map, and, if the infrastructure runs simultaneously with the scan, real-time display of the reconstructed data during the scan and automated alerts for patient motion. Methods: A fast ray-tracing time-of-flight projector was implemented and parallelized. The reconstruction parameters were optimized to allow for fast performance: only a few iterations are performed, without point-spread-function modeling, and scatter correction is not used. The resulting reconstructions are thus not quantitative but are acceptable for motion estimation and visualization purposes. Data-driven motion can be estimated using image registration, with the resultant motion data being used in a fully motion-corrected list-mode reconstruction. Results: The infrastructure provided images that can be used for visualization and gating purposes and for motion estimation using image registration. Several case studies are presented, including data-driven motion estimation and correction for brain studies, abdominal studies in which respiratory and cardiac motion is visible, and a whole-body survey. Conclusion: The presented infrastructure provides the capability to quickly create a series of very short frames for PET data that can be used in a variety of applications.

  • fast reconstruction
  • list-mode reconstruction
  • real-time reconstruction
  • data-driven motion correction

Footnotes

  • Published online Jul. 9, 2020.

  • © 2021 by the Society of Nuclear Medicine and Molecular Imaging.
View Full Text

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.

SNMMI members

SNMMI Member Login

Login to the site using your SNMMI member credentials

Individuals

Non-Member Login

Login as an individual user

PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 62 (2)
Journal of Nuclear Medicine
Vol. 62, Issue 2
February 1, 2021
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications
Matthew G. Spangler-Bickell, Timothy W. Deller, Valentino Bettinardi, Floris Jansen
Journal of Nuclear Medicine Feb 2021, 62 (2) 287-292; DOI: 10.2967/jnumed.120.245597

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications
Matthew G. Spangler-Bickell, Timothy W. Deller, Valentino Bettinardi, Floris Jansen
Journal of Nuclear Medicine Feb 2021, 62 (2) 287-292; DOI: 10.2967/jnumed.120.245597
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Abstract
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSION
    • DISCLOSURE
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF

Related Articles

  • This Month in JNM
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

Physics and Instrumentation

  • Investigating Low-Dose Image Quality in Whole-Body Pediatric 18F-FDG Scans Using Time-of-Flight PET/MRI
  • Data-Driven Respiratory Gating Outperforms Device-Based Gating for Clinical 18F-FDG PET/CT
Show more Physics and Instrumentation

Clinical

  • Diagnostic Performance of Pulmonary Embolism Imaging in Patients with History of Asthma
  • Head-to-Head Evaluation of 18F-FES and 18F-FDG PET/CT in Metastatic Invasive Lobular Breast Cancer
  • Peptide Receptor Radionuclide Therapy of Late-Stage Neuroendocrine Tumor Patients with Multiple Cycles of 177Lu-DOTA-EB-TATE
Show more Clinical

Similar Articles

Keywords

  • fast reconstruction
  • list-mode reconstruction
  • real-time reconstruction
  • data-driven motion correction
SNMMI

© 2021 Journal of Nuclear Medicine

Powered by HighWire