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Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout de Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt and Karine Breckpot
Journal of Nuclear Medicine November 2021, 62 (11) 1638-1644; DOI: https://doi.org/10.2967/jnumed.120.258871
Quentin Lecocq
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Robin Maximilian Awad
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Yannick De Vlaeminck
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Wout de Mey
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Thomas Ertveldt
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Cleo Goyvaerts
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Geert Raes
2Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium;
3Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium;
Kris Thielemans
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
Marleen Keyaerts
4In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium; and
5Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
Nick Devoogdt
4In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium; and
Karine Breckpot
1Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium;
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Journal of Nuclear Medicine
Vol. 62, Issue 11
November 1, 2021
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout de Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot
Journal of Nuclear Medicine Nov 2021, 62 (11) 1638-1644; DOI: 10.2967/jnumed.120.258871
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout de Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot
Journal of Nuclear Medicine Nov 2021, 62 (11) 1638-1644; DOI: 10.2967/jnumed.120.258871
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