Overview and Analysis of the Utility of 1- and 3-Hour 99mTechnetium-Pyrophosphate Planar and SPECT/CT Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis

Nicholas Link; Matthew Curry; Yitong Fu

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Overview and Analysis of the Utility of 1- and 3-Hour 99mTechnetium-Pyrophosphate Planar and SPECT/CT Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis

Nicholas Link, Matthew Curry and Yitong Fu

Journal of Nuclear Medicine May 2020, 61 (supplement 1) 1611;

Nicholas Link

1University of Tennessee Knoxville Knoxville TN United States

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Matthew Curry

1University of Tennessee Knoxville Knoxville TN United States

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Yitong Fu

2University of TN Medical Center at Knoxville Knoxville TN United States

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Quantifying myocardial 99mTechnetium-Pyrophosphate uptake utilizing 1-hour planar imaging H/L ratio
Negative H/L ratio of less than 1
Equivocal H/L ratio of 1.0-1.5
Strongly Suggestive H/L ratio greater than 1.5

Semi-quantitative Visual Grading of Myocardial 99mTechnetium-Pyrophosphate Uptake Relative to Rib

Grade 0	No myocardial uptake and normal bone uptake
Grade 1	Myocardial uptake less than rib uptake
Grade 2	Myocardial uptake equal to rib uptake
Grade 3	Myocardial uptake greater than rib uptake with mild/absent rib uptake

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Journal of Nuclear Medicine

Vol. 61, Issue supplement 1

May 1, 2020

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Overview and Analysis of the Utility of 1- and 3-Hour 99mTechnetium-Pyrophosphate Planar and SPECT/CT Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis

Nicholas Link, Matthew Curry, Yitong Fu

Journal of Nuclear Medicine May 2020, 61 (supplement 1) 1611;

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Overview and Analysis of the Utility of 1- and 3-Hour 99mTechnetium-Pyrophosphate Planar and SPECT/CT Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis

Nicholas Link, Matthew Curry, Yitong Fu

Journal of Nuclear Medicine May 2020, 61 (supplement 1) 1611;

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Overview and Analysis of the Utility of 1- and 3-Hour 99mTechnetium-Pyrophosphate Planar and SPECT/CT Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis

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Negative	H/L ratio of less than 1
Equivocal	H/L ratio of 1.0-1.5
Strongly Suggestive	H/L ratio greater than 1.5