Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of 18F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

Santiago Bullich; Olivier Barret; Cristian Constantinescu; Christine Sandiego; Andre Mueller; Mathias Berndt; Caroline Papin; Audrey Perrotin; Norman Koglin; Heiko Kroth; Andrea Pfeifer; Gilles Tamagnan; Jennifer Madonia; John P. Seibyl; Kenneth Marek; Susan De Santi; Ludger M. Dinkelborg; Andrew W. Stephens

doi:10.2967/jnumed.119.236240

Research ArticleNeurology

Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of ¹⁸F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

Santiago Bullich, Olivier Barret, Cristian Constantinescu, Christine Sandiego, Andre Mueller, Mathias Berndt, Caroline Papin, Audrey Perrotin, Norman Koglin, Heiko Kroth, Andrea Pfeifer, Gilles Tamagnan, Jennifer Madonia, John P. Seibyl, Kenneth Marek, Susan De Santi, Ludger M. Dinkelborg and Andrew W. Stephens

Journal of Nuclear Medicine June 2020, 61 (6) 920-927; DOI: https://doi.org/10.2967/jnumed.119.236240

Santiago Bullich

1Life Molecular Imaging GmbH, Berlin, Germany

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Olivier Barret

2Invicro, New Haven, Connecticut

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Cristian Constantinescu

2Invicro, New Haven, Connecticut

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Christine Sandiego

2Invicro, New Haven, Connecticut

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Andre Mueller

1Life Molecular Imaging GmbH, Berlin, Germany

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Mathias Berndt

1Life Molecular Imaging GmbH, Berlin, Germany

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Caroline Papin

1Life Molecular Imaging GmbH, Berlin, Germany

2Invicro, New Haven, Connecticut

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Audrey Perrotin

1Life Molecular Imaging GmbH, Berlin, Germany

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Norman Koglin

1Life Molecular Imaging GmbH, Berlin, Germany

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Heiko Kroth

3AC Immune SA, Lausanne, Switzerland; and

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Andrea Pfeifer

3AC Immune SA, Lausanne, Switzerland; and

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Gilles Tamagnan

2Invicro, New Haven, Connecticut

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Jennifer Madonia

2Invicro, New Haven, Connecticut

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John P. Seibyl

2Invicro, New Haven, Connecticut

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Kenneth Marek

2Invicro, New Haven, Connecticut

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Susan De Santi

4Life Molecular Imaging Inc., Boston, Massachusetts

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Ludger M. Dinkelborg

1Life Molecular Imaging GmbH, Berlin, Germany

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Andrew W. Stephens

1Life Molecular Imaging GmbH, Berlin, Germany

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Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of ¹⁸F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

Journal of Nuclear Medicine Jun 2020, 61 (6) 920-927; DOI: 10.2967/jnumed.119.236240

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Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of ¹⁸F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

Journal of Nuclear Medicine Jun 2020, 61 (6) 920-927; DOI: 10.2967/jnumed.119.236240

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tau PET
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Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of ¹⁸F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

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