Abstract
1285
Purpose: The purpose of this study is to compare PET/MR imaging to that of PET/CT in patients with cancer. Materials and Methods: Thirty-two patients with cancer underwent whole body simultaneous 18F-FDG PET/CT and PET/MR on the same day with a single standard administration of FDG. All the patients had a complete clinical data. All patients fasted for 4-6 hours before imaging. 185-296MBq of 18F-FDG was administered. PET/CT was started 60 minutes after injection of FDG on uMI 510 PET/CT scanner(Shanghai United Imaging healthcare Co.). Simultaneous 18F-FDG PET/MR was performed on uPMR 790(Shanghai United Imaging healthcare Co. )began 120-150 minutes after FDG injection. whole body(from vertex to the mid thigh)in a five-bed-position axial scan with PET, T1-weighted , T2-weighted imaging, WFI, FSE, SSFSE, Flair ,EPI,STIR sequences were collected. PET/CT and PET/MR images were evaluated by 2 physicians separately. A combination of biopsy, surgical pathology, and clinical and imaging follow-up were used as reference standard.
Results: PET/CT and PET/MR findings were fully concordant in 18 patients(56.25%). PET/MR imaging revealed additional findings not seen at PET/CT in 11 patients(34.38%).PET/CT revealed additional findings not seen on PET/MR images in 3 patients with small lung nodules.
Conclusions: PET/MR imaging might be more useful than PET/CT in lymph node and intraspinal metastasis evaluation. Lung nodules are difficult to be shown on MR images, and Thin-slice spiral CT of lung is necessary in PET/MR imaging. Quantitative software of Domestic PET/MR still needs further improvement.(This study was partially supported by funding from Key Specialty Construction Project of Pudong Health and Family Planning Commission of Shanghai, PWZzk2017-24)