Abstract
1240
Objectives: To review the incidence of new breast cancer lesions in patients with dense breast, using breast mammography and compared it with high resolution breast PET. To review all the indications of high resolution breast PET. To verify that the fusion of breast mammography with high resolution breast PET is optimum.
Methods: We review all the patients in the data base from 2016 to 2018. We include only patients with breast mammography that were done in the institution in order to perform the fusion with the high resolution breast PET. A total of 105 patients with dense breast were included.
Results: 29 patients with a breast density of D (4) and 76 patients had a breast density of C (3). 40 right, 59 left and 6 bilateral lesions. Invasive ductal breast cancer was the most common. In 6 patients, all with breast density of D (4), had bilateral lesions, not suspected in the mammography. 16 patients with suspected mammography were negative with high resolution breast PET, 5 with breast density of D (4). In 8 patients with implants, in 5 the high resolution breast PET was positive, in 3 was negative, one with previous lesion and treatment with surgery and chemotherapy and two with family antecedent of cancer, one of them with breast density D (4). 16 patients had multifocal disease, 15 had multicentric disease, 16 had intraductal disease. In 34 patients the high definition breast PET contributed with more information than the breast mammography. In some patients we can conclude that the tumor was going to the nipple. With high resolution breast PET was easy to distinguish between a single or multiple focus.
Conclusions: The digital breast mammography and other techniques continue to be standard methods in breast cancer screening. The metabolism of 18FDG is higher in malignant cells in breast cancer than in normal cells, it manifests as increased uptake of the radiotracer in High Resolution Breast PET. The fusion provides morphological and metabolic information to distinguish and recognize breast cancer. High resolution breast PET is not affected by breast density. High resolution breast PET is not affected by hormonal status. High definition breast PET contributed with more information than the breast mammography. In the patients with implants the high resolution breast PET was very useful. High Resolution Breast PET with the combination of mammography can show breast cancer, as a multifocal or multicentric disease and in some cases show intraductal involvement.