Journal of Nuclear Medicine: 60 (7)

July 1, 2019; Volume 60,Issue 7

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine July 1, 2019, 60 (7) 8A;

Discussions with Leaders

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A Conversation Between Susanne Schaffert and Ken Herrmann
Susanne Schaffert and Ken Herrmann

Journal of Nuclear Medicine July 1, 2019, 60 (7) 875-878; DOI: https://doi.org/10.2967/jnumed.119.231035

Hot Topics

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Imaging of CAR T-Cells in Cancer Patients: Paving the Way to Treatment Monitoring and Outcome Prediction
Simone Krebs, Vladimir Ponomarev, Susan Slovin and Heiko Schöder

Journal of Nuclear Medicine July 1, 2019, 60 (7) 879-881; DOI: https://doi.org/10.2967/jnumed.119.227561

The State of the Art

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Evaluating the Role of Theranostics in Grade 3 Neuroendocrine Neoplasms
Najeff Waseem, Carina Mari Aparici and Pamela L. Kunz

Journal of Nuclear Medicine July 1, 2019, 60 (7) 882-891; DOI: https://doi.org/10.2967/jnumed.118.217851

Continuing Education

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Advanced Imaging in Cardiac Sarcoidosis
Roberto Ramirez, Maria Trivieri, Zahi A. Fayad, Amir Ahmadi, Jagat Narula and Edgar Argulian

Journal of Nuclear Medicine July 1, 2019, 60 (7) 892-898; DOI: https://doi.org/10.2967/jnumed.119.228130

Oncology

Clinical
- INVITED PERSPECTIVE
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    Immuno-PET to Optimize the Dose of Monoclonal Antibodies for Cancer Therapy: How Much Is Enough?
    Raymond M. Reilly
    
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 899-901; DOI: https://doi.org/10.2967/jnumed.119.225854
- FEATURED ARTICLE OF THE MONTH
  - Open Access
    Immuno-PET Imaging to Assess Target Engagement: Experience from ⁸⁹Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors
    C. Willemien Menke-van der Houven van Oordt, Adam McGeoch, Mats Bergstrom, Iain McSherry, Deborah A. Smith, Matthew Cleveland, Wasfi Al-Azzam, Liangfu Chen, Henk Verheul, Otto S. Hoekstra, Danielle J. Vugts, Immanuel Freedman, Marc Huisman, Chris Matheny, Guus van Dongen and Sean Zhang
    
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 902-909; DOI: https://doi.org/10.2967/jnumed.118.214726
Translational
- FEATURED TRANSLATIONAL SCIENCE ARTICLE
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    Phase I Study of CTT1057, an ¹⁸F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer
    Spencer C. Behr, Rahul Aggarwal, Henry F. VanBrocklin, Robert R. Flavell, Kenneth Gao, Eric J. Small, Joseph Blecha, Salma Jivan, Thomas A. Hope, Jeffry P. Simko, John Kurhanewicz, Susan M. Noworolski, Natalie J. Korn, Romelyn De Los Santos, Matthew R. Cooperberg, Peter R. Carroll, Hao G. Nguyen, Kirsten L. Greene, Beatrice Langton-Webster, Clifford E. Berkman and Youngho Seo
    
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 910-916; DOI: https://doi.org/10.2967/jnumed.118.220715
Basic
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  MEK Inhibition Induces Therapeutic Iodine Uptake in a Murine Model of Anaplastic Thyroid Cancer
  Oussama ElMokh, Vincent Taelman, Piotr Radojewski, Matthias A. Roelli, Amandine Stoss, Rebecca A. Dumont, Matthias S. Dettmer, Wayne A. Phillips, Martin A. Walter and Roch-Philippe Charles
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 917-923; DOI: https://doi.org/10.2967/jnumed.118.216721
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  N-(2-(Dimethylamino)Ethyl)-4-¹⁸F-Fluorobenzamide: A Novel Molecular Probe for High-Contrast PET Imaging of Malignant Melanoma
  Ayoung Pyo, Hyeon Sik Kim, Hyung Seok Kim, Misun Yun, Dong-Yeon Kim and Jung-Joon Min
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 924-929; DOI: https://doi.org/10.2967/jnumed.118.221416
- FEATURED BASIC SCIENCE ARTICLE
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    P2X7 PET Radioligand ¹⁸F-PTTP for Differentiation of Lung Tumor from Inflammation
    Zhequan Fu, Qingyu Lin, Bingxin Hu, Yingying Zhang, Weijia Chen, Jing Zhu, Yanzhao Zhao, Hak Soo Choi, Hongcheng Shi and Dengfeng Cheng
    
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 930-936; DOI: https://doi.org/10.2967/jnumed.118.222547

Theranostics

Clinical
- SPECIAL CONTRIBUTION
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    NANETS/SNMMI Procedure Standard for Somatostatin Receptor–Based Peptide Receptor Radionuclide Therapy with ¹⁷⁷Lu-DOTATATE
    Thomas A. Hope, Amanda Abbott, Karen Colucci, David L. Bushnell, Linda Gardner, William S. Graham, Sheila Lindsay, David C. Metz, Daniel A. Pryma, Michael G. Stabin and Jonathan R. Strosberg
    
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 937-943; DOI: https://doi.org/10.2967/jnumed.118.230607
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  Combination of ⁶⁸Ga-PSMA PET/CT and Multiparametric MRI Improves the Detection of Clinically Significant Prostate Cancer: A Lesion-by-Lesion Analysis
  Mengxia Chen, Qing Zhang, Chengwei Zhang, Xiaozhi Zhao, Giancarlo Marra, Jie Gao, Xiaoyu Lv, Bing Zhang, Yao Fu, Feng Wang, Xuefeng Qiu and Hongqian Guo
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 944-949; DOI: https://doi.org/10.2967/jnumed.118.221010
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  Rapid Modulation of PSMA Expression by Androgen Deprivation: Serial ⁶⁸Ga-PSMA-11 PET in Men with Hormone-Sensitive and Castrate-Resistant Prostate Cancer Commencing Androgen Blockade
  Louise Emmett, Charlotte Yin, Megan Crumbaker, George Hruby, Andrew Kneebone, Richard Epstein, Quoc Nguyen, Adam Hickey, Noah Ihsheish, Gordon O’Neill, Lisa Horvath, Venu Chalasani, Phillip Stricker and Anthony M. Joshua
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 950-954; DOI: https://doi.org/10.2967/jnumed.118.223099
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  Clinical Outcomes of ¹⁷⁷Lu-PSMA Radioligand Therapy in Earlier and Later Phases of Metastatic Castration-Resistant Prostate Cancer Grouped by Previous Taxane Chemotherapy
  Thomas W. Barber, Aviral Singh, Harshad R. Kulkarni, Karin Niepsch, Baki Billah and Richard P. Baum
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 955-962; DOI: https://doi.org/10.2967/jnumed.118.216820
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  Impact of ⁶⁸Ga-PSMA PET/CT on the Radiotherapeutic Approach to Prostate Cancer in Comparison to CT: A Retrospective Analysis
  Nina-Sophie Schmidt-Hegemann, Chukwuka Eze, Minglun Li, Paul Rogowski, Christian Schaefer, Christian Stief, Alexander Buchner, Constantinos Zamboglou, Wolfgang Peter Fendler, Ute Ganswindt, Clemens Cyran, Peter Bartenstein, Claus Belka and Harun Ilhan
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 963-970; DOI: https://doi.org/10.2967/jnumed.118.220855
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  Detection Rate of ¹⁸F-Choline PET/CT and ⁶⁸Ga-PSMA-HBED-CC PET/CT for Prostate Cancer Lymph Node Metastases with Direct Link from PET to Histopathology: Dependence on the Size of Tumor Deposits in Lymph Nodes
  Cordula A. Jilg, Vanessa Drendel, H. Christian Rischke, Teresa I. Beck, Kathrin Reichel, Malte Krönig, Ulrich Wetterauer, Wolfgang Schultze-Seemann, Philipp T. Meyer and Werner Vach
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 971-977; DOI: https://doi.org/10.2967/jnumed.118.220541

Neurology

Clinical
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  Automatic Extraction of a Reference Region for the Noninvasive Quantification of Translocator Protein in Brain Using ¹¹C-PBR28
  Paolo Zanotti-Fregonara, William C. Kreisl, Robert B. Innis and Chul Hyoung Lyoo
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 978-984; DOI: https://doi.org/10.2967/jnumed.118.222927
Translational
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  Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate ¹¹C-Metoclopramide Assessed with PET Imaging in Humans
  Nicolas Tournier, Martin Bauer, Verena Pichler, Lukas Nics, Eva-Maria Klebermass, Karsten Bamminger, Peter Matzneller, Maria Weber, Rudolf Karch, Fabien Caillé, Sylvain Auvity, Solène Marie, Walter Jäger, Wolfgang Wadsak, Marcus Hacker, Markus Zeitlinger and Oliver Langer
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 985-991; DOI: https://doi.org/10.2967/jnumed.118.219972
Basic
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  Quantitative Analysis of ¹⁸F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
  Akihiro Takano, Laigao Chen, Sangram Nag, Michael A. Brodney, Ryosuke Arakawa, Cheng Chang, Nahid Amini, Shawn D. Doran, Jason K. Dutra, Timothy J. McCarthy, Charles E. Nolan, Brian T. O’Neill, Anabella Villalobos, Lei Zhang and Christer Halldin
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 992-997; DOI: https://doi.org/10.2967/jnumed.118.217372

Infectious Disease

Clinical
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  ¹⁸F-FDG PET/CT–Guided Treatment Duration in Patients with High-Risk Staphylococcus Aureus Bacteremia: A Proof of Principle
  Marvin A.H. Berrevoets, Ilse J.E. Kouijzer, Kitty Slieker, Erik H.J.G. Aarntzen, Bart Jan Kullberg, Jaap Ten Oever and Chantal P. Bleeker-Rovers
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 998-1002; DOI: https://doi.org/10.2967/jnumed.118.221929

Radiochemistry

Basic
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  ¹⁸F-Branched-Chain Amino Acids: Structure–Activity Relationships and PET Imaging Potential
  Matthew B. Nodwell, Hua Yang, Helen Merkens, Noeen Malik, Milena Čolović, Björn Wagner, Rainer E. Martin, François Bénard, Paul Schaffer and Robert Britton
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 1003-1009; DOI: https://doi.org/10.2967/jnumed.118.220483
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  DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use
  Maximilian Klingler, Dominik Summer, Christine Rangger, Roland Haubner, Julie Foster, Jane Sosabowski, Clemens Decristoforo, Irene Virgolini and Elisabeth von Guggenberg
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 1010-1016; DOI: https://doi.org/10.2967/jnumed.118.221283
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  In Vitro and In Vivo Characterization of an ¹⁸F-AlF-Labeled PSMA Ligand for Imaging of PSMA-Expressing Xenografts
  Susanne Lütje, Gerben M. Franssen, Ken Herrmann, Otto C. Boerman, Mark Rijpkema, Martin Gotthardt and Sandra Heskamp
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 1017-1022; DOI: https://doi.org/10.2967/jnumed.118.218941
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  Development and In Vivo Evaluation of a κ-Opioid Receptor Agonist as a PET Radiotracer with Superior Imaging Characteristics
  Songye Li, Ming-Qiang Zheng, Mika Naganawa, Sujin Kim, Hong Gao, Michael Kapinos, David Labaree and Yiyun Huang
  
  Journal of Nuclear Medicine July 1, 2019, 60 (7) 1023-1030; DOI: https://doi.org/10.2967/jnumed.118.220517

Instrumentation

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Performance Characteristics of the Digital Biograph Vision PET/CT System
Joyce van Sluis, Johan de Jong, Jenny Schaar, Walter Noordzij, Paul van Snick, Rudi Dierckx, Ronald Borra, Antoon Willemsen and Ronald Boellaard

Journal of Nuclear Medicine July 1, 2019, 60 (7) 1031-1036; DOI: https://doi.org/10.2967/jnumed.118.215418

Erratum

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Erratum
Journal of Nuclear Medicine July 1, 2019, 60 (7) 1030;

SNMMI Newsline

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NRC Training and Experience Requirements for Radiopharmaceuticals Requiring a Written Directive
Journal of Nuclear Medicine July 1, 2019, 60 (7) 9N-12N;
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The Distinction Between an AU and an ABNM-Certified MD
George M. Segall

Journal of Nuclear Medicine July 1, 2019, 60 (7) 10N;
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In Memoriam: Monte Blau, PhD, 1926–2019
Hank F. Kung, Karen C. Rosenspire and Robert H. Mach

Journal of Nuclear Medicine July 1, 2019, 60 (7) 11N-12N;
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SNMMI Leadership Update: Influx of New Ideas and Opportunities Collaboration Propels Growth
Vasken Dilsizian

Journal of Nuclear Medicine July 1, 2019, 60 (7) 13N;
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Lawhn-Heath Named 2019 Henkin Fellow
Journal of Nuclear Medicine July 1, 2019, 60 (7) 14N;
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Newsbriefs
Journal of Nuclear Medicine July 1, 2019, 60 (7) 14N-16N;
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From the Literature
Journal of Nuclear Medicine July 1, 2019, 60 (7) 16N-19N;

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Table of Contents

This Month in JNM

Discussions with Leaders

Hot Topics

The State of the Art

Continuing Education

Oncology

Clinical

INVITED PERSPECTIVE

FEATURED ARTICLE OF THE MONTH

Translational

FEATURED TRANSLATIONAL SCIENCE ARTICLE

Basic

FEATURED BASIC SCIENCE ARTICLE

Theranostics

Clinical

SPECIAL CONTRIBUTION

Neurology

Clinical

Translational

Basic

Infectious Disease

Clinical

Radiochemistry

Basic

Instrumentation

Erratum

SNMMI Newsline

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