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Journal of Nuclear Medicine

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Table of Contents

July 1, 2019; Volume 60,Issue 7

This Month in JNM

  • You have access
    This Month in JNM
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 8A;

Discussions with Leaders

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    A Conversation Between Susanne Schaffert and Ken Herrmann
    Susanne Schaffert and Ken Herrmann
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 875-878; DOI: https://doi.org/10.2967/jnumed.119.231035

Hot Topics

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    Imaging of CAR T-Cells in Cancer Patients: Paving the Way to Treatment Monitoring and Outcome Prediction
    Simone Krebs, Vladimir Ponomarev, Susan Slovin and Heiko Schöder
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 879-881; DOI: https://doi.org/10.2967/jnumed.119.227561

The State of the Art

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    Evaluating the Role of Theranostics in Grade 3 Neuroendocrine Neoplasms
    Najeff Waseem, Carina Mari Aparici and Pamela L. Kunz
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 882-891; DOI: https://doi.org/10.2967/jnumed.118.217851

Continuing Education

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    Advanced Imaging in Cardiac Sarcoidosis
    Roberto Ramirez, Maria Trivieri, Zahi A. Fayad, Amir Ahmadi, Jagat Narula and Edgar Argulian
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 892-898; DOI: https://doi.org/10.2967/jnumed.119.228130

Oncology

  • Clinical

    • INVITED PERSPECTIVE

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        Immuno-PET to Optimize the Dose of Monoclonal Antibodies for Cancer Therapy: How Much Is Enough?
        Raymond M. Reilly
        Journal of Nuclear Medicine July 1, 2019, 60 (7) 899-901; DOI: https://doi.org/10.2967/jnumed.119.225854
    • FEATURED ARTICLE OF THE MONTH

      • Open Access
        Immuno-PET Imaging to Assess Target Engagement: Experience from 89Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors
        C. Willemien Menke-van der Houven van Oordt, Adam McGeoch, Mats Bergstrom, Iain McSherry, Deborah A. Smith, Matthew Cleveland, Wasfi Al-Azzam, Liangfu Chen, Henk Verheul, Otto S. Hoekstra, Danielle J. Vugts, Immanuel Freedman, Marc Huisman, Chris Matheny, Guus van Dongen and Sean Zhang
        Journal of Nuclear Medicine July 1, 2019, 60 (7) 902-909; DOI: https://doi.org/10.2967/jnumed.118.214726
  • Translational

    • FEATURED TRANSLATIONAL SCIENCE ARTICLE

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        Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer
        Spencer C. Behr, Rahul Aggarwal, Henry F. VanBrocklin, Robert R. Flavell, Kenneth Gao, Eric J. Small, Joseph Blecha, Salma Jivan, Thomas A. Hope, Jeffry P. Simko, John Kurhanewicz, Susan M. Noworolski, Natalie J. Korn, Romelyn De Los Santos, Matthew R. Cooperberg, Peter R. Carroll, Hao G. Nguyen, Kirsten L. Greene, Beatrice Langton-Webster, Clifford E. Berkman and Youngho Seo
        Journal of Nuclear Medicine July 1, 2019, 60 (7) 910-916; DOI: https://doi.org/10.2967/jnumed.118.220715
  • Basic

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      MEK Inhibition Induces Therapeutic Iodine Uptake in a Murine Model of Anaplastic Thyroid Cancer
      Oussama ElMokh, Vincent Taelman, Piotr Radojewski, Matthias A. Roelli, Amandine Stoss, Rebecca A. Dumont, Matthias S. Dettmer, Wayne A. Phillips, Martin A. Walter and Roch-Philippe Charles
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 917-923; DOI: https://doi.org/10.2967/jnumed.118.216721
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      N-(2-(Dimethylamino)Ethyl)-4-18F-Fluorobenzamide: A Novel Molecular Probe for High-Contrast PET Imaging of Malignant Melanoma
      Ayoung Pyo, Hyeon Sik Kim, Hyung Seok Kim, Misun Yun, Dong-Yeon Kim and Jung-Joon Min
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 924-929; DOI: https://doi.org/10.2967/jnumed.118.221416
    • FEATURED BASIC SCIENCE ARTICLE

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        P2X7 PET Radioligand 18F-PTTP for Differentiation of Lung Tumor from Inflammation
        Zhequan Fu, Qingyu Lin, Bingxin Hu, Yingying Zhang, Weijia Chen, Jing Zhu, Yanzhao Zhao, Hak Soo Choi, Hongcheng Shi and Dengfeng Cheng
        Journal of Nuclear Medicine July 1, 2019, 60 (7) 930-936; DOI: https://doi.org/10.2967/jnumed.118.222547

Theranostics

  • Clinical

    • SPECIAL CONTRIBUTION

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        NANETS/SNMMI Procedure Standard for Somatostatin Receptor–Based Peptide Receptor Radionuclide Therapy with 177Lu-DOTATATE
        Thomas A. Hope, Amanda Abbott, Karen Colucci, David L. Bushnell, Linda Gardner, William S. Graham, Sheila Lindsay, David C. Metz, Daniel A. Pryma, Michael G. Stabin and Jonathan R. Strosberg
        Journal of Nuclear Medicine July 1, 2019, 60 (7) 937-943; DOI: https://doi.org/10.2967/jnumed.118.230607
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      Combination of 68Ga-PSMA PET/CT and Multiparametric MRI Improves the Detection of Clinically Significant Prostate Cancer: A Lesion-by-Lesion Analysis
      Mengxia Chen, Qing Zhang, Chengwei Zhang, Xiaozhi Zhao, Giancarlo Marra, Jie Gao, Xiaoyu Lv, Bing Zhang, Yao Fu, Feng Wang, Xuefeng Qiu and Hongqian Guo
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 944-949; DOI: https://doi.org/10.2967/jnumed.118.221010
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      Rapid Modulation of PSMA Expression by Androgen Deprivation: Serial 68Ga-PSMA-11 PET in Men with Hormone-Sensitive and Castrate-Resistant Prostate Cancer Commencing Androgen Blockade
      Louise Emmett, Charlotte Yin, Megan Crumbaker, George Hruby, Andrew Kneebone, Richard Epstein, Quoc Nguyen, Adam Hickey, Noah Ihsheish, Gordon O’Neill, Lisa Horvath, Venu Chalasani, Phillip Stricker and Anthony M. Joshua
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 950-954; DOI: https://doi.org/10.2967/jnumed.118.223099
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      Clinical Outcomes of 177Lu-PSMA Radioligand Therapy in Earlier and Later Phases of Metastatic Castration-Resistant Prostate Cancer Grouped by Previous Taxane Chemotherapy
      Thomas W. Barber, Aviral Singh, Harshad R. Kulkarni, Karin Niepsch, Baki Billah and Richard P. Baum
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 955-962; DOI: https://doi.org/10.2967/jnumed.118.216820
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      Impact of 68Ga-PSMA PET/CT on the Radiotherapeutic Approach to Prostate Cancer in Comparison to CT: A Retrospective Analysis
      Nina-Sophie Schmidt-Hegemann, Chukwuka Eze, Minglun Li, Paul Rogowski, Christian Schaefer, Christian Stief, Alexander Buchner, Constantinos Zamboglou, Wolfgang Peter Fendler, Ute Ganswindt, Clemens Cyran, Peter Bartenstein, Claus Belka and Harun Ilhan
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 963-970; DOI: https://doi.org/10.2967/jnumed.118.220855
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      Detection Rate of 18F-Choline PET/CT and 68Ga-PSMA-HBED-CC PET/CT for Prostate Cancer Lymph Node Metastases with Direct Link from PET to Histopathology: Dependence on the Size of Tumor Deposits in Lymph Nodes
      Cordula A. Jilg, Vanessa Drendel, H. Christian Rischke, Teresa I. Beck, Kathrin Reichel, Malte Krönig, Ulrich Wetterauer, Wolfgang Schultze-Seemann, Philipp T. Meyer and Werner Vach
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 971-977; DOI: https://doi.org/10.2967/jnumed.118.220541

Neurology

  • Clinical

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      Automatic Extraction of a Reference Region for the Noninvasive Quantification of Translocator Protein in Brain Using 11C-PBR28
      Paolo Zanotti-Fregonara, William C. Kreisl, Robert B. Innis and Chul Hyoung Lyoo
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 978-984; DOI: https://doi.org/10.2967/jnumed.118.222927
  • Translational

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      Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate 11C-Metoclopramide Assessed with PET Imaging in Humans
      Nicolas Tournier, Martin Bauer, Verena Pichler, Lukas Nics, Eva-Maria Klebermass, Karsten Bamminger, Peter Matzneller, Maria Weber, Rudolf Karch, Fabien Caillé, Sylvain Auvity, Solène Marie, Walter Jäger, Wolfgang Wadsak, Marcus Hacker, Markus Zeitlinger and Oliver Langer
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 985-991; DOI: https://doi.org/10.2967/jnumed.118.219972
  • Basic

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      Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
      Akihiro Takano, Laigao Chen, Sangram Nag, Michael A. Brodney, Ryosuke Arakawa, Cheng Chang, Nahid Amini, Shawn D. Doran, Jason K. Dutra, Timothy J. McCarthy, Charles E. Nolan, Brian T. O’Neill, Anabella Villalobos, Lei Zhang and Christer Halldin
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 992-997; DOI: https://doi.org/10.2967/jnumed.118.217372

Infectious Disease

  • Clinical

    • You have access
      18F-FDG PET/CT–Guided Treatment Duration in Patients with High-Risk Staphylococcus Aureus Bacteremia: A Proof of Principle
      Marvin A.H. Berrevoets, Ilse J.E. Kouijzer, Kitty Slieker, Erik H.J.G. Aarntzen, Bart Jan Kullberg, Jaap Ten Oever and Chantal P. Bleeker-Rovers
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 998-1002; DOI: https://doi.org/10.2967/jnumed.118.221929

Radiochemistry

  • Basic

    • You have access
      18F-Branched-Chain Amino Acids: Structure–Activity Relationships and PET Imaging Potential
      Matthew B. Nodwell, Hua Yang, Helen Merkens, Noeen Malik, Milena Čolović, Björn Wagner, Rainer E. Martin, François Bénard, Paul Schaffer and Robert Britton
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 1003-1009; DOI: https://doi.org/10.2967/jnumed.118.220483
    • You have access
      DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use
      Maximilian Klingler, Dominik Summer, Christine Rangger, Roland Haubner, Julie Foster, Jane Sosabowski, Clemens Decristoforo, Irene Virgolini and Elisabeth von Guggenberg
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 1010-1016; DOI: https://doi.org/10.2967/jnumed.118.221283
    • You have access
      In Vitro and In Vivo Characterization of an 18F-AlF-Labeled PSMA Ligand for Imaging of PSMA-Expressing Xenografts
      Susanne Lütje, Gerben M. Franssen, Ken Herrmann, Otto C. Boerman, Mark Rijpkema, Martin Gotthardt and Sandra Heskamp
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 1017-1022; DOI: https://doi.org/10.2967/jnumed.118.218941
    • You have access
      Development and In Vivo Evaluation of a κ-Opioid Receptor Agonist as a PET Radiotracer with Superior Imaging Characteristics
      Songye Li, Ming-Qiang Zheng, Mika Naganawa, Sujin Kim, Hong Gao, Michael Kapinos, David Labaree and Yiyun Huang
      Journal of Nuclear Medicine July 1, 2019, 60 (7) 1023-1030; DOI: https://doi.org/10.2967/jnumed.118.220517

Instrumentation

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    Performance Characteristics of the Digital Biograph Vision PET/CT System
    Joyce van Sluis, Johan de Jong, Jenny Schaar, Walter Noordzij, Paul van Snick, Rudi Dierckx, Ronald Borra, Antoon Willemsen and Ronald Boellaard
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 1031-1036; DOI: https://doi.org/10.2967/jnumed.118.215418

Erratum

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    Erratum
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 1030;

SNMMI Newsline

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    NRC Training and Experience Requirements for Radiopharmaceuticals Requiring a Written Directive
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 9N-12N;
  • You have access
    The Distinction Between an AU and an ABNM-Certified MD
    George M. Segall
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 10N;
  • You have access
    In Memoriam: Monte Blau, PhD, 1926–2019
    Hank F. Kung, Karen C. Rosenspire and Robert H. Mach
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 11N-12N;
  • You have access
    SNMMI Leadership Update: Influx of New Ideas and Opportunities Collaboration Propels Growth
    Vasken Dilsizian
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 13N;
  • You have access
    Lawhn-Heath Named 2019 Henkin Fellow
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 14N;
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    Newsbriefs
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 14N-16N;
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    From the Literature
    Journal of Nuclear Medicine July 1, 2019, 60 (7) 16N-19N;
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In this issue

Journal of Nuclear Medicine: 60 (7)
Journal of Nuclear Medicine
Vol. 60, Issue 7
July 1, 2019
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Immuno-PET Imaging to Assess Target Engagement: Experience from 89Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors
  • P2X7 PET Radioligand 18F-PTTP for Differentiation of Lung Tumor from Inflammation
  • Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer
  • Evaluating the Role of Theranostics in Grade 3 Neuroendocrine Neoplasms
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      • INVITED PERSPECTIVE
      • FEATURED ARTICLE OF THE MONTH
    • Translational
      • FEATURED TRANSLATIONAL SCIENCE ARTICLE
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      • FEATURED BASIC SCIENCE ARTICLE
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  • Neurology
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  • Absorbed Dose–Response Relationship in Patients with Gastroenteropancreatic Neuroendocrine Tumors Treated with [177Lu]Lu-DOTATATE: One Step Closer to Personalized Medicine
  • MIRD Pamphlet No. 28, Part 1: MIRDcalc—A Software Tool for Medical Internal Radiation Dosimetry
  • Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study
  • High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
  • Total-Body Perfusion Imaging with [11C]-Butanol
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