Fully Automated 89Zr Labeling and Purification of Antibodies

Alex J. Poot; Kevin W.A. Adamzek; Albert D. Windhorst; Maria J.W.D. Vosjan; Saskia Kropf; Hans-Jurgen Wester; Guus A.M.S. van Dongen; Danielle J. Vugts

doi:10.2967/jnumed.118.217158

Research ArticleRadiochemistry

Fully Automated ⁸⁹Zr Labeling and Purification of Antibodies

Alex J. Poot, Kevin W.A. Adamzek, Albert D. Windhorst, Maria J.W.D. Vosjan, Saskia Kropf, Hans-Jurgen Wester, Guus A.M.S. van Dongen and Danielle J. Vugts

Journal of Nuclear Medicine May 2019, 60 (5) 691-695; DOI: https://doi.org/10.2967/jnumed.118.217158

Alex J. Poot

1Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

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Kevin W.A. Adamzek

1Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

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Albert D. Windhorst

1Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

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Maria J.W.D. Vosjan

2BV Cyclotron VU, Amsterdam, The Netherlands

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Saskia Kropf

3Scintomics GmbH, Fuerstenfeldbruck, Germany; and

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Hans-Jurgen Wester

3Scintomics GmbH, Fuerstenfeldbruck, Germany; and

4Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany

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Guus A.M.S. van Dongen

1Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

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Danielle J. Vugts

1Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

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Journal of Nuclear Medicine

Vol. 60, Issue 5

May 1, 2019

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Fully Automated ⁸⁹Zr Labeling and Purification of Antibodies

Alex J. Poot, Kevin W.A. Adamzek, Albert D. Windhorst, Maria J.W.D. Vosjan, Saskia Kropf, Hans-Jurgen Wester, Guus A.M.S. van Dongen, Danielle J. Vugts

Journal of Nuclear Medicine May 2019, 60 (5) 691-695; DOI: 10.2967/jnumed.118.217158

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Fully Automated ⁸⁹Zr Labeling and Purification of Antibodies

Alex J. Poot, Kevin W.A. Adamzek, Albert D. Windhorst, Maria J.W.D. Vosjan, Saskia Kropf, Hans-Jurgen Wester, Guus A.M.S. van Dongen, Danielle J. Vugts

Journal of Nuclear Medicine May 2019, 60 (5) 691-695; DOI: 10.2967/jnumed.118.217158

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Keywords

automation
89Zr
Antibody Labeling
positron emission tomography
radiopharmaceuticals
Good Manufacturing Practice

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