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Journal of Nuclear Medicine

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Table of Contents

February 1, 2019; Volume 60,Issue 2

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 6A;

Leadership Perspectives

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    Discussions with Leaders: A Conversation Between Steven Larson and Johannes Czernin
    Steven M. Larson and Johannes Czernin
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 151-155;

Hot Topics

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    Entering the Era of Molecularly Targeted Precision Surgery in Recurrent Prostate Cancer
    Tobias Maurer, Fijs W.B. van Leeuwen, Margret Schottelius, Hans-Jürgen Wester and Matthias Eiber
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 156-157; DOI: https://doi.org/10.2967/jnumed.118.221861

Continuing Education

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    Harmonization of U.S., European Union, and Canadian First-in-Human Regulatory Requirements for Radiopharmaceuticals: Is This Possible?
    Sally W. Schwarz, Clemens Decristoforo, Anne E. Goodbody, Nikhita Singhal, Sarah Saliba, Patrick S. Ruddock, Katherine Zukotynski and Andrew A. Ross
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 158-166; DOI: https://doi.org/10.2967/jnumed.118.209460

Focus on Molecular Imaging

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    New Developments in Peptide Receptor Radionuclide Therapy
    Guillaume P. Nicolas, Alfred Morgenstern, Margret Schottelius and Melpomeni Fani
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 167-171; DOI: https://doi.org/10.2967/jnumed.118.213496

Oncology

  • Clinical

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      Long-Term Effects of Radioiodine Treatment on Salivary Gland Function in Adult Survivors of Pediatric Differentiated Thyroid Carcinoma
      Tharsana Selvakumar, Marloes Nies, Mariëlle S. Klein Hesselink, Adrienne H. Brouwers, Anouk N.A. van der Horst-Schrivers, Esther N. Klein Hesselink, Wim J.E. Tissing, Arjan Vissink and Thera P. Links; on behalf of the Dutch Pediatric Thyroid Cancer Study Consortium
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 172-177; DOI: https://doi.org/10.2967/jnumed.118.212449
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      Validation of Metabolically Active Tumor Volume and Total Lesion Glycolysis as 18F-FDG PET/CT–derived Prognostic Biomarkers in Chemorefractory Metastatic Colorectal Cancer
      Erwin Woff, Alain Hendlisz, Lieveke Ameye, Camilo Garcia, Tarek Kamoun, Thomas Guiot, Marianne Paesmans and Patrick Flamen
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 178-184; DOI: https://doi.org/10.2967/jnumed.118.210161
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      68Ga-Labeled Prostate-Specific Membrane Antigen Is a Novel PET/CT Tracer for Imaging of Hepatocellular Carcinoma: A Prospective Pilot Study
      Mikhail Kesler, Charles Levine, Dov Hershkovitz, Eyal Mishani, Yoram Menachem, Hedva Lerman, Yaniv Zohar, Oren Shibolet and Einat Even-Sapir
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 185-191; DOI: https://doi.org/10.2967/jnumed.118.214833
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      Prognostic Value of Standardized Uptake Ratio in Patients with Trimodality Treatment of Locally Advanced Esophageal Carcinoma
      Rebecca Bütof, Frank Hofheinz, Klaus Zöphel, Julia Schmollack, Christina Jentsch, Sebastian Zschaeck, Jörg Kotzerke, Jörg van den Hoff and Michael Baumann
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 192-198; DOI: https://doi.org/10.2967/jnumed.117.207670
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      Radiomics in Vulvar Cancer: First Clinical Experience Using 18F-FDG PET/CT Images
      Angela Collarino, Giorgia Garganese, Simona M. Fragomeni, Lenka M. Pereira Arias-Bouda, Francesco P. Ieria, Ronald Boellaard, Vittoria Rufini, Lioe-Fee de Geus-Oei, Giovanni Scambia, Renato A. Valdés Olmos, Alessandro Giordano, Willem Grootjans and Floris HP van Velden
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 199-206; DOI: https://doi.org/10.2967/jnumed.118.215889
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      Metabolic Tumor Volume for Response Prediction in Advanced-Stage Hodgkin Lymphoma
      Jasmin Mettler, Horst Müller, Conrad-Amadeus Voltin, Christian Baues, Bernd Klaeser, Alden Moccia, Peter Borchmann, Andreas Engert, Georg Kuhnert, Alexander Drzezga, Markus Dietlein and Carsten Kobe
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 207-211; DOI: https://doi.org/10.2967/jnumed.118.210047
  • Basic

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      Hexokinase 2 Is Targetable for HK1-Negative, HK2-Positive Tumors from a Wide Variety of Tissues of Origin
      Shili Xu, Arthur Catapang, Hanna M. Doh, Nicholas A. Bayley, Jason T. Lee, Daniel Braas, Thomas G. Graeber and Harvey R. Herschman
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 212-217; DOI: https://doi.org/10.2967/jnumed.118.212365
    • INVITED PERSPECTIVE

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        Measuring Estrogen Receptor Functionality Using Progesterone Receptor PET Imaging: Rising to the (Estradiol) Challenge!
        Michel Paquette and Éric E. Turcotte
        Journal of Nuclear Medicine February 1, 2019, 60 (2) 218-219; DOI: https://doi.org/10.2967/jnumed.118.220921
    • FEATURED BASIC SCIENCE ARTICLE

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        Sensitivity and Isoform Specificity of 18F-Fluorofuranylnorprogesterone for Measuring Progesterone Receptor Protein Response to Estradiol Challenge in Breast Cancer
        Kelley Salem, Manoj Kumar, Yongjun Yan, Justin J. Jeffery, Kyle C. Kloepping, Ciara J. Michel, Ginny L. Powers, Aparna M. Mahajan and Amy M. Fowler
        Journal of Nuclear Medicine February 1, 2019, 60 (2) 220-226; DOI: https://doi.org/10.2967/jnumed.118.211516

Theranostics

  • Clinical

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      Outcome After PSMA PET/CT–Based Salvage Radiotherapy in Patients with Biochemical Recurrence After Radical Prostatectomy: A 2-Institution Retrospective Analysis
      Nina-Sophie Schmidt-Hegemann, Christian Stief, Tak-Hyun Kim, Chukwuka Eze, Simon Kirste, Iosif Strouthos, Minglun Li, Wolfgang Schultze-Seemann, Harun Ilhan, Wolfgang Peter Fendler, Peter Bartenstein, Anca-Ligia Grosu, Ute Ganswindt, Claus Belka, Philipp T. Meyer and Constantinos Zamboglou
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 227-233; DOI: https://doi.org/10.2967/jnumed.118.212563
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      68Ga-PSMA-11 PET/CT in Primary and Recurrent Prostate Carcinoma: Implications for Radiotherapeutic Management in 121 Patients
      Stefan A. Koerber, Leon Will, Clemens Kratochwil, Matthias F. Haefner, Hendrik Rathke, Christophe Kremer, Jonas Merkle, Klaus Herfarth, Klaus Kopka, Peter L. Choyke, Tim Holland-Letz, Uwe Haberkorn, Juergen Debus and Frederik L. Giesel
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 234-240; DOI: https://doi.org/10.2967/jnumed.118.211086

Neurology

  • Clinical

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      Use of 18F-ASEM PET to Determine the Availability of the α7-Nicotinic Acetylcholine Receptor in Recent-Onset Psychosis
      Jennifer M. Coughlin, Yong Du, Jeffrey L. Crawford, Leah H. Rubin, Babak Behnam Azad, Wojciech G. Lesniak, Andrew G. Horti, David J. Schretlen, Akira Sawa and Martin G. Pomper
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 241-243; DOI: https://doi.org/10.2967/jnumed.118.213686

Pulmonary

  • Clinical

    • FEATURED ARTICLE OF THE MONTH

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        Glycoprotein IIb/IIIa Receptor Imaging with 18F-GP1 PET for Acute Venous Thromboembolism: An Open-Label, Nonrandomized, Phase 1 Study
        Chanwoo Kim, Jae Seung Lee, Youngjin Han, Sun Young Chae, Soyoung Jin, Changhwan Sung, Hye Joo Son, Seung Jun Oh, Sang Ju Lee, Jungsu S. Oh, Yong-Pil Cho, Tae-Won Kwon, Deok Hee Lee, Seongsoo Jang, Bohyun Kim, Norman Koglin, Mathias Berndt, Andrew W. Stephens and Dae Hyuk Moon
        Journal of Nuclear Medicine February 1, 2019, 60 (2) 244-249; DOI: https://doi.org/10.2967/jnumed.118.212084

Radiobiology/Dosimetry

  • Clinical

    • Open Access
      Targeting Micrometastases: The Effect of Heterogeneous Radionuclide Distribution on Tumor Control Probability
      Nadia Falzone, Boon Quan Lee, Sarah Able, Javian Malcolm, Samantha Terry, Yasir Alayed and Katherine A. Vallis
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 250-258; DOI: https://doi.org/10.2967/jnumed.117.207308

Radiochemistry

  • Basic

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      Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor
      Ahmed Haider, Irina Iten, Hazem Ahmed, Adrienne Müller Herde, Stefan Gruber, Stefanie D. Krämer, Claudia Keller, Roger Schibli, Bernhard Wünsch, Linjing Mu and Simon M. Ametamey
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 259-266; DOI: https://doi.org/10.2967/jnumed.118.212134

Molecular Imaging

  • Clinical

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      Assessment of Physiologic Intracranial Calcification in Healthy Adults Using 18F-NaF PET/CT
      Abdullah Al-Zaghal, Siavash Mehdizadeh Seraj, Thomas J. Werner, Oke Gerke, Poul F. Høilund-Carlsen and Abass Alavi
      Journal of Nuclear Medicine February 1, 2019, 60 (2) 267-271; DOI: https://doi.org/10.2967/jnumed.118.213678

Physics And Instrumentation

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    An Efficient Approach to Perform MR-Assisted PET Data Optimization in Simultaneous PET/MR Neuroimaging Studies
    Kevin T. Chen, Stephanie Salcedo, Kuang Gong, Daniel B. Chonde, David Izquierdo-Garcia, Alexander Drzezga, Bruce Rosen, Jinyi Qi, Bradford C. Dickerson and Ciprian Catana
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 272-278; DOI: https://doi.org/10.2967/jnumed.117.207142
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    Evaluation of a Novel Elastic Respiratory Motion Correction Algorithm on Quantification and Image Quality in Abdominothoracic PET/CT
    Joseph G. Meier, Carol C. Wu, Sonia L. Betancourt Cuellar, Mylene T. Truong, Jeremy J. Erasmus, Samuel A. Einstein and Osama R. Mawlawi
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 279-284; DOI: https://doi.org/10.2967/jnumed.118.213884
  • Open Access
    Spatial Normalization of 18F-Flutemetamol PET Images Using an Adaptive Principal-Component Template
    Johan Lilja, Antoine Leuzy, Konstantinos Chiotis, Irina Savitcheva, Jens Sörensen and Agneta Nordberg
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 285-291; DOI: https://doi.org/10.2967/jnumed.118.207811

Letters to the Editor

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    The War Is Opened: PSMA vs. 64CUCL2 vs. Choline PET/CT
    Laura Evangelista and Fabio Zattoni
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 292; DOI: https://doi.org/10.2967/jnumed.118.218289
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    Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
    Yang Lu and Nadera J. Sweiss
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 292-293; DOI: https://doi.org/10.2967/jnumed.118.221549
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    Reply: Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
    Panithaya Chareonthaitawee and Ron Blankstein
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 293-294; DOI: https://doi.org/10.2967/jnumed.118.221879

SNMMI Newsline

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    SNMMI and NCI Theranostics Consensus Conference 2018
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 7N;
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    FDA Releases New Draft Guidance on Compounded Drugs
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 8N;
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    SNMMI Leadership Update: SNMMI Efforts Supporting Nuclear Medicine Therapy
    Satoshi Minoshima
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 9N-18N;
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    Newsbriefs
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 10N-11N;
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    From the Literature
    Journal of Nuclear Medicine February 1, 2019, 60 (2) 12N-18N;
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In this issue

Journal of Nuclear Medicine: 60 (2)
Journal of Nuclear Medicine
Vol. 60, Issue 2
February 1, 2019
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Glycoprotein IIb/IIIa Receptor Imaging with 18F-GP1 PET for Acute Venous Thromboembolism: An Open-Label, Nonrandomized, Phase 1 Study
  • Sensitivity and Isoform Specificity of 18F-Fluorofuranylnorprogesterone for Measuring Progesterone Receptor Protein Response to Estradiol Challenge in Breast Cancer
  • Entering the Era of Molecularly Targeted Precision Surgery in Recurrent Prostate Cancer
  • Harmonization of U.S., European Union, and Canadian First-in-Human Regulatory Requirements for Radiopharmaceuticals: Is This Possible?
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      • FEATURED BASIC SCIENCE ARTICLE
  • Theranostics
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      • FEATURED ARTICLE OF THE MONTH
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  • Long-Term Follow-up and Outcomes of Retreatment in an Expanded 50-Patient Single-Center Phase II Prospective Trial of 177Lu-PSMA-617 Theranostics in Metastatic Castration-Resistant Prostate Cancer
  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Impact of 68Ga-PSMA-11 PET/CT on Staging and Management of Prostate Cancer Patients in Various Clinical Settings: A Prospective Single-Center Study
  • Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
  • Radiation Dosimetry in 177Lu-PSMA-617 Therapy Using a Single Posttreatment SPECT/CT Scan: A Novel Methodology to Generate Time- and Tissue-Specific Dose Factors
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