Journal of Nuclear Medicine: 59 (6)

June 1, 2018; Volume 59,Issue 6

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine June 1, 2018, 59 (6) 10A;

Hot Topics

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Now Is the Time to Use ¹⁸F-FDG PET/CT to Optimize Neoadjuvant Treatment in Triple-Negative Breast Cancer!
David Groheux

Journal of Nuclear Medicine June 1, 2018, 59 (6) 863-864; DOI: https://doi.org/10.2967/jnumed.118.210922

Issues and Controversies

INVITED PERSPECTIVE
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  Perspective on How the FDA Should Review Diagnostic Radiopharmaceuticals
  Sally W. Schwarz and Bonnie Clarke
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 865-867; DOI: https://doi.org/10.2967/jnumed.117.204446
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How Should the FDA Review Diagnostic Radiopharmaceuticals?
Carol S. Marcus

Journal of Nuclear Medicine June 1, 2018, 59 (6) 868-870; DOI: https://doi.org/10.2967/jnumed.117.200337

The State of the Art

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Imaging of Nonprostate Cancers Using PSMA-Targeted Radiotracers: Rationale, Current State of the Field, and a Call to Arms
Roberto A. Salas Fragomeni, Tali Amir, Sara Sheikhbahaei, Susan C. Harvey, Mehrbod S. Javadi, Lilja B. Solnes, Ana P. Kiess, Mohamad E. Allaf, Martin G. Pomper, Michael A. Gorin and Steven P. Rowe

Journal of Nuclear Medicine June 1, 2018, 59 (6) 871-877; DOI: https://doi.org/10.2967/jnumed.117.203570

Continuing Education

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α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies—Part 1
Sophie Poty, Lynn C. Francesconi, Michael R. McDevitt, Michael J. Morris and Jason S. Lewis

Journal of Nuclear Medicine June 1, 2018, 59 (6) 878-884; DOI: https://doi.org/10.2967/jnumed.116.186338

Focus on Molecular Imaging

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Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology
Ahmet Krasniqi, Matthias D’Huyvetter, Nick Devoogdt, Fredrik Y. Frejd, Jens Sörensen, Anna Orlova, Marleen Keyaerts and Vladimir Tolmachev

Journal of Nuclear Medicine June 1, 2018, 59 (6) 885-891; DOI: https://doi.org/10.2967/jnumed.117.199901

Oncology

Clinical
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  Glioma Survival Prediction with Combined Analysis of In Vivo ¹¹C-MET PET Features, Ex Vivo Features, and Patient Features by Supervised Machine Learning
  László Papp, Nina Pötsch, Marko Grahovac, Victor Schmidbauer, Adelheid Woehrer, Matthias Preusser, Markus Mitterhauser, Barbara Kiesel, Wolfgang Wadsak, Thomas Beyer, Marcus Hacker and Tatjana Traub-Weidinger
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 892-899; DOI: https://doi.org/10.2967/jnumed.117.202267
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  First-in-Human Human Epidermal Growth Factor Receptor 2–Targeted Imaging Using ⁸⁹Zr-Pertuzumab PET/CT: Dosimetry and Clinical Application in Patients with Breast Cancer
  Gary A. Ulaner, Serge K. Lyashchenko, Christopher Riedl, Shutian Ruan, Pat B. Zanzonico, Diana Lake, Komal Jhaveri, Brian Zeglis, Jason S. Lewis and Joseph A. O’Donoghue
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 900-906; DOI: https://doi.org/10.2967/jnumed.117.202010

Theranostics

Clinical
- INVITED PERSPECTIVE
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    Somatostatin Receptor Imaging of Neuroendocrine Tumors: From Agonists to Antagonists
    Lisa Bodei and Wolfgang A. Weber
    
    Journal of Nuclear Medicine June 1, 2018, 59 (6) 907-908; DOI: https://doi.org/10.2967/jnumed.117.205161
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    Safety, Biodistribution, and Radiation Dosimetry of ⁶⁸Ga-OPS202 in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase I Imaging Study
    Guillaume P. Nicolas, Seval Beykan, Hakim Bouterfa, Jens Kaufmann, Andreas Bauman, Michael Lassmann, Jean Claude Reubi, Jean E.F. Rivier, Helmut R. Maecke, Melpomeni Fani and Damian Wild
    
    Journal of Nuclear Medicine June 1, 2018, 59 (6) 909-914; DOI: https://doi.org/10.2967/jnumed.117.199737
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  Sensitivity Comparison of ⁶⁸Ga-OPS202 and ⁶⁸Ga-DOTATOC PET/CT in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase II Imaging Study
  Guillaume P. Nicolas, Nils Schreiter, Felix Kaul, John Uiters, Hakim Bouterfa, Jens Kaufmann, Tobias E. Erlanger, Richard Cathomas, Emanuel Christ, Melpomeni Fani and Damian Wild
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 915-921; DOI: https://doi.org/10.2967/jnumed.117.199760
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  PET Using a GRPR Antagonist ⁶⁸Ga-RM26 in Healthy Volunteers and Prostate Cancer Patients
  Jingjing Zhang, Gang Niu, Xinrong Fan, Lixin Lang, Guozhu Hou, Libo Chen, Huanwen Wu, Zhaohui Zhu, Fang Li and Xiaoyuan Chen
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 922-928; DOI: https://doi.org/10.2967/jnumed.117.198929
- BRIEF COMMUNICATION
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    The Effect of Total Tumor Volume on the Biologically Effective Dose to Tumor and Kidneys for ¹⁷⁷Lu-Labeled PSMA Peptides
    Nusrat J. Begum, Anne Thieme, Nina Eberhardt, Robert Tauber, Calogero D’Alessandria, Ambros J. Beer, Gerhard Glatting, Matthias Eiber and Peter Kletting
    
    Journal of Nuclear Medicine June 1, 2018, 59 (6) 929-933; DOI: https://doi.org/10.2967/jnumed.117.203505
- INVITED PERSPECTIVE
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    Penetrating the Barriers to Successful α-Radioimmunotherapy
    Sean Carlin
    
    Journal of Nuclear Medicine June 1, 2018, 59 (6) 934-936; DOI: https://doi.org/10.2967/jnumed.117.205146

Neurology

Clinical
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  Test–Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18
  Michael D. Devous, Abhinay D. Joshi, Michael Navitsky, Sudeepti Southekal, Michael J. Pontecorvo, Haiqing Shen, Ming Lu, William R. Shankle, John P. Seibyl, Ken Marek and Mark A. Mintun
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 937-943; DOI: https://doi.org/10.2967/jnumed.117.200691
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  Flortaucipir F 18 Quantitation Using Parametric Estimation of Reference Signal Intensity
  Sudeepti Southekal, Michael D. Devous, Ian Kennedy, Michael Navitsky, Ming Lu, Abhinay D. Joshi, Michael J. Pontecorvo and Mark A. Mintun
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 944-951; DOI: https://doi.org/10.2967/jnumed.117.200006
Basic
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  Glutamatergic Biomarkers for Cocaine Addiction: A Longitudinal Study Using MR Spectroscopy and mGluR5 PET in Self-Administering Rats
  Bart de Laat, Akila Weerasekera, Gil Leurquin-Sterk, Guy Bormans, Uwe Himmelreich, Cindy Casteels and Koen Van Laere
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 952-959; DOI: https://doi.org/10.2967/jnumed.117.202614
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  Comparative In Vitro and In Vivo Quantifications of Pathologic Tau Deposits and Their Association with Neurodegeneration in Tauopathy Mouse Models
  Ruiqing Ni, Bin Ji, Maiko Ono, Naruhiko Sahara, Ming-Rong Zhang, Ichio Aoki, Agneta Nordberg, Tetsuya Suhara and Makoto Higuchi
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 960-966; DOI: https://doi.org/10.2967/jnumed.117.201632

Musculoskeletal

Clinical
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  ¹⁸F-FDG PET/MRI in Chronic Sciatica: Early Results Revealing Spinal and Nonspinal Abnormalities
  Peter W. Cipriano, Daehyun Yoon, Harsh Gandhi, Dawn Holley, Dushyant Thakur, Brian A. Hargreaves, David J. Kennedy, Matthew W. Smuck, Ivan Cheng and Sandip Biswal
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 967-972; DOI: https://doi.org/10.2967/jnumed.117.198259

Radiochemistry

Clinical
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  Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood–Brain Barrier Using Elacridar and ¹¹C-Erlotinib PET
  Remy B. Verheijen, Maqsood Yaqub, Emilia Sawicki, Olaf van Tellingen, Adriaan A. Lammertsma, Bastiaan Nuijen, Jan H.M. Schellens, Jos H. Beijnen, Alwin D.R. Huitema, N. Harry Hendrikse and Neeltje Steeghs
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 973-979; DOI: https://doi.org/10.2967/jnumed.117.195800

Inflammation/Infectious Disease

Basic
- FEATURED ARTICLE OF THE MONTH
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    Immuno-PET in Inflammatory Bowel Disease: Imaging CD4-Positive T Cells in a Murine Model of Colitis
    Amanda C. Freise, Kirstin A. Zettlitz, Felix B. Salazar, Richard Tavaré, Wen-Ting K. Tsai, Arion F. Chatziioannou, Nora Rozengurt, Jonathan Braun and Anna M. Wu
    
    Journal of Nuclear Medicine June 1, 2018, 59 (6) 980-985; DOI: https://doi.org/10.2967/jnumed.117.199075

Molecular Imaging

Basic
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  Tracers for Fluorescence-Guided Surgery: How Elongation of the Polymethine Chain in Cyanine Dyes Alters the Pharmacokinetics of a Dual-Modality c[RGDyK] Tracer
  Tessa Buckle, Danny M. van Willigen, Silvia J. Spa, Albertus W. Hensbergen, Steffen van der Wal, Clarize M. de Korne, Mick M. Welling, Henk G. van der Poel, James C.H. Hardwick and Fijs W.B. van Leeuwen
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 986-992; DOI: https://doi.org/10.2967/jnumed.117.205575

Physics and Instrumentation

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Development and Evaluation of mini-EXPLORER: A Long Axial Field-of-View PET Scanner for Nonhuman Primate Imaging
Eric Berg, Xuezhu Zhang, Julien Bec, Martin S. Judenhofer, Brijesh Patel, Qiyu Peng, Maciej Kapusta, Matthias Schmand, Michael E. Casey, Alice F. Tarantal, Jinyi Qi, Ramsey D. Badawi and Simon R. Cherry

Journal of Nuclear Medicine June 1, 2018, 59 (6) 993-998; DOI: https://doi.org/10.2967/jnumed.117.200519
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Reproducibility of MR-Based Attenuation Maps in PET/MRI and the Impact on PET Quantification in Lung Cancer
Anders Olin, Claes N. Ladefoged, Natasha H. Langer, Sune H. Keller, Johan Löfgren, Adam E. Hansen, Andreas Kjær, Seppo W. Langer, Barbara M. Fischer and Flemming L. Andersen

Journal of Nuclear Medicine June 1, 2018, 59 (6) 999-1004; DOI: https://doi.org/10.2967/jnumed.117.198853

Radiobiology/Dosimetry

SPECIAL CONTRIBUTION
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  New-Generation Fetal Dose Estimates for Radiopharmaceuticals
  Michael G. Stabin
  
  Journal of Nuclear Medicine June 1, 2018, 59 (6) 1005-1006; DOI: https://doi.org/10.2967/jnumed.117.204214

Erratum

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Erratum
Journal of Nuclear Medicine June 1, 2018, 59 (6) 992;

SNMMI Newsline

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NIH Completes Genomic Analysis of 33 Cancer Types
Journal of Nuclear Medicine June 1, 2018, 59 (6) 11N-12N;
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Outstanding JNMT Articles for 2017
Journal of Nuclear Medicine June 1, 2018, 59 (6) 12N;
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Proceedings of the NCI SBIR Workshop on Molecularly Targeted Radionuclide Therapy
Christie A. Canaria, M. Lisa Yeom, Jacek Capala and Deepa Narayanan

Journal of Nuclear Medicine June 1, 2018, 59 (6) 13N-14N;
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Outstanding JNM Articles for 2017
Journal of Nuclear Medicine June 1, 2018, 59 (6) 15N;
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ABNM Support for Research During Training
George M. Segall

Journal of Nuclear Medicine June 1, 2018, 59 (6) 16N;
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SNMMI Leadership Update: Implementing the Value Initiative
Bennett S. Greenspan

Journal of Nuclear Medicine June 1, 2018, 59 (6) 17N-18N;
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Aria Razmaria, MD, Awarded 2018 Henkin Fellowship
Journal of Nuclear Medicine June 1, 2018, 59 (6) 18N;
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Newsbriefs
Journal of Nuclear Medicine June 1, 2018, 59 (6) 19N-20N;
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From the Literature
Journal of Nuclear Medicine June 1, 2018, 59 (6) 21N-22N;

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Table of Contents

This Month in JNM

Hot Topics

Issues and Controversies

INVITED PERSPECTIVE

The State of the Art

Continuing Education

Focus on Molecular Imaging

Oncology

Clinical

Theranostics

Clinical

INVITED PERSPECTIVE

FEATURED CLINICAL INVESTIGATION ARTICLE

BRIEF COMMUNICATION

INVITED PERSPECTIVE

Neurology

Clinical

Basic

Musculoskeletal

Clinical

Radiochemistry

Clinical

Inflammation/Infectious Disease

Basic

FEATURED ARTICLE OF THE MONTH

Molecular Imaging

Basic

Physics and Instrumentation

Radiobiology/Dosimetry

SPECIAL CONTRIBUTION

Erratum

SNMMI Newsline

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