Research ArticleInflammation/Infection
In Vivo Hypoxia PET Imaging Quantifies the Severity of Arthritic Joint Inflammation in Line with Overexpression of Hypoxia-Inducible Factor and Enhanced Reactive Oxygen Species Generation
Kerstin Fuchs, Anna Kuehn, Moritz Mahling, Philipp Guenthoer, Andreas Hector, Johannes Schwenck, Dominik Hartl, Stefan Laufer, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Gerald Reischl, Martin Röcken, Bernd J. Pichler and Manfred Kneilling
Journal of Nuclear Medicine May 2017, 58 (5) 853-860; DOI: https://doi.org/10.2967/jnumed.116.185934
Kerstin Fuchs
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Anna Kuehn
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Moritz Mahling
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Philipp Guenthoer
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Andreas Hector
2Children’s Hospital of the Eberhard Karls University Tuebingen, Tuebingen, Germany
Johannes Schwenck
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
3Department of Nuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University, Tuebingen, Tuebingen, Germany
Dominik Hartl
2Children’s Hospital of the Eberhard Karls University Tuebingen, Tuebingen, Germany
4Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Pharma Research & Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland
Stefan Laufer
5Department of Pharmacy & Biochemistry, Eberhard Karls University Tuebingen, Tuebingen, Germany
Ursula Kohlhofer
6Institute of Pathology and Neuropathology, Eberhard Karls University Tuebingen and Comprehensive Cancer Center, University Hospital Tuebingen, Tuebingen, Germany; and
Leticia Quintanilla-Martinez
6Institute of Pathology and Neuropathology, Eberhard Karls University Tuebingen and Comprehensive Cancer Center, University Hospital Tuebingen, Tuebingen, Germany; and
Gerald Reischl
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Martin Röcken
7Department of Dermatology, Eberhard Karls University Tuebingen, Tuebingen, Germany
Bernd J. Pichler
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
Manfred Kneilling
1Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, Tuebingen, Germany
7Department of Dermatology, Eberhard Karls University Tuebingen, Tuebingen, Germany
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Journal of Nuclear Medicine
Vol. 58, Issue 5
May 1, 2017
In Vivo Hypoxia PET Imaging Quantifies the Severity of Arthritic Joint Inflammation in Line with Overexpression of Hypoxia-Inducible Factor and Enhanced Reactive Oxygen Species Generation
Kerstin Fuchs, Anna Kuehn, Moritz Mahling, Philipp Guenthoer, Andreas Hector, Johannes Schwenck, Dominik Hartl, Stefan Laufer, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Gerald Reischl, Martin Röcken, Bernd J. Pichler, Manfred Kneilling
Journal of Nuclear Medicine May 2017, 58 (5) 853-860; DOI: 10.2967/jnumed.116.185934
In Vivo Hypoxia PET Imaging Quantifies the Severity of Arthritic Joint Inflammation in Line with Overexpression of Hypoxia-Inducible Factor and Enhanced Reactive Oxygen Species Generation
Kerstin Fuchs, Anna Kuehn, Moritz Mahling, Philipp Guenthoer, Andreas Hector, Johannes Schwenck, Dominik Hartl, Stefan Laufer, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Gerald Reischl, Martin Röcken, Bernd J. Pichler, Manfred Kneilling
Journal of Nuclear Medicine May 2017, 58 (5) 853-860; DOI: 10.2967/jnumed.116.185934
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