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Review ArticleContinuing Education

Quantification of Lung PET Images: Challenges and Opportunities

Delphine L. Chen, Joseph Cheriyan, Edwin R. Chilvers, Gourab Choudhury, Christopher Coello, Martin Connell, Marie Fisk, Ashley M. Groves, Roger N. Gunn, Beverley F. Holman, Brian F. Hutton, Sarah Lee, William MacNee, Divya Mohan, David Parr, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Edwin J.R. van Beek, Laurence Vass, Jeremy W. Wellen, Ian Wilkinson and Frederick J. Wilson
Journal of Nuclear Medicine February 2017, 58 (2) 201-207; DOI: https://doi.org/10.2967/jnumed.116.184796
Delphine L. Chen
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri
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Joseph Cheriyan
2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
3Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
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Edwin R. Chilvers
2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
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Gourab Choudhury
4Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Christopher Coello
5Imanova Ltd., London, United Kingdom
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Martin Connell
4Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Marie Fisk
2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
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Ashley M. Groves
6Institute of Nuclear Medicine, University College London, London, United Kingdom
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Roger N. Gunn
5Imanova Ltd., London, United Kingdom
7Department of Medicine, Imperial College London, London, United Kingdom
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Beverley F. Holman
6Institute of Nuclear Medicine, University College London, London, United Kingdom
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Brian F. Hutton
6Institute of Nuclear Medicine, University College London, London, United Kingdom
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Sarah Lee
8Medical Image Analysis Consultant, London, United Kingdom
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William MacNee
4Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Divya Mohan
9Clinical Discovery, Respiratory Therapy Area Unit, GlaxoSmithKline R&D, King of Prussia, Pennsylvania
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David Parr
10University Hospitals Coventry and Warwickshire, Coventry, United Kingdom
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Deepak Subramanian
11Derby Teaching Hospitals NHS Foundation Trust, Derby, United Kingdom
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Ruth Tal-Singer
9Clinical Discovery, Respiratory Therapy Area Unit, GlaxoSmithKline R&D, King of Prussia, Pennsylvania
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Kris Thielemans
6Institute of Nuclear Medicine, University College London, London, United Kingdom
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Edwin J.R. van Beek
4Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Laurence Vass
2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
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Jeremy W. Wellen
12Worldwide Research and Development, Pfizer, Inc., Cambridge, Massachusetts; and
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Ian Wilkinson
2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
3Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
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Frederick J. Wilson
13Experimental Medicine Imaging, GlaxoSmithKline, Stevenage, United Kingdom
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Article Information

vol. 58 no. 2 201-207
DOI 
https://doi.org/10.2967/jnumed.116.184796
PubMed 
28082432

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 1, 2016
  • Accepted for publication January 10, 2017
  • Published online February 1, 2017.

Article Versions

  • previous version (January 12, 2017 - 04:47).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Delphine L. Chen1,
  2. Joseph Cheriyan2,3,
  3. Edwin R. Chilvers2,
  4. Gourab Choudhury4,
  5. Christopher Coello5,
  6. Martin Connell4,
  7. Marie Fisk2,
  8. Ashley M. Groves6,
  9. Roger N. Gunn5,7,
  10. Beverley F. Holman6,
  11. Brian F. Hutton6,
  12. Sarah Lee8,
  13. William MacNee4,
  14. Divya Mohan9,
  15. David Parr10,
  16. Deepak Subramanian11,
  17. Ruth Tal-Singer9,
  18. Kris Thielemans6,
  19. Edwin J.R. van Beek4,
  20. Laurence Vass2,
  21. Jeremy W. Wellen12,
  22. Ian Wilkinson2,3 and
  23. Frederick J. Wilson13
  1. 1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri
  2. 2Department of Medicine, University of Cambridge, Cambridge, United Kingdom
  3. 3Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
  4. 4Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
  5. 5Imanova Ltd., London, United Kingdom
  6. 6Institute of Nuclear Medicine, University College London, London, United Kingdom
  7. 7Department of Medicine, Imperial College London, London, United Kingdom
  8. 8Medical Image Analysis Consultant, London, United Kingdom
  9. 9Clinical Discovery, Respiratory Therapy Area Unit, GlaxoSmithKline R&D, King of Prussia, Pennsylvania
  10. 10University Hospitals Coventry and Warwickshire, Coventry, United Kingdom
  11. 11Derby Teaching Hospitals NHS Foundation Trust, Derby, United Kingdom
  12. 12Worldwide Research and Development, Pfizer, Inc., Cambridge, Massachusetts; and
  13. 13Experimental Medicine Imaging, GlaxoSmithKline, Stevenage, United Kingdom
  1. For correspondence or reprints contact: Delphine L. Chen, Washington University School of Medicine, Campus Box 8225, 510 S. Kingshighway Blvd., St. Louis, MO 63110. E-mail: chend{at}wustl.edu
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Journal of Nuclear Medicine: 58 (2)
Journal of Nuclear Medicine
Vol. 58, Issue 2
February 1, 2017
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Quantification of Lung PET Images: Challenges and Opportunities
Delphine L. Chen, Joseph Cheriyan, Edwin R. Chilvers, Gourab Choudhury, Christopher Coello, Martin Connell, Marie Fisk, Ashley M. Groves, Roger N. Gunn, Beverley F. Holman, Brian F. Hutton, Sarah Lee, William MacNee, Divya Mohan, David Parr, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Edwin J.R. van Beek, Laurence Vass, Jeremy W. Wellen, Ian Wilkinson, Frederick J. Wilson
Journal of Nuclear Medicine Feb 2017, 58 (2) 201-207; DOI: 10.2967/jnumed.116.184796

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Quantification of Lung PET Images: Challenges and Opportunities
Delphine L. Chen, Joseph Cheriyan, Edwin R. Chilvers, Gourab Choudhury, Christopher Coello, Martin Connell, Marie Fisk, Ashley M. Groves, Roger N. Gunn, Beverley F. Holman, Brian F. Hutton, Sarah Lee, William MacNee, Divya Mohan, David Parr, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Edwin J.R. van Beek, Laurence Vass, Jeremy W. Wellen, Ian Wilkinson, Frederick J. Wilson
Journal of Nuclear Medicine Feb 2017, 58 (2) 201-207; DOI: 10.2967/jnumed.116.184796
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  • Article
    • Abstract
    • CLINICAL APPLICATIONS INVESTIGATED WITH 18F-FDG PET IMAGING
    • ANALYSIS METHODS AND THEIR APPLICATIONS IN LUNG DISEASES
    • ISSUES AND SUGGESTED CONSIDERATIONS
    • CONCLUSION
    • Footnotes
    • REFERENCES
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Keywords

  • Pulmonary
  • lung inflammation
  • molecular imaging
  • positron emission tomography
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