Research ArticleNeurology
Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease
Steven Deleye, Ann-Marie Waldron, Jeroen Verhaeghe, Astrid Bottelbergs, Leonie Wyffels, Bianca Van Broeck, Xavier Langlois, Mark Schmidt, Sigrid Stroobants and Steven Staelens
Journal of Nuclear Medicine December 2017, 58 (12) 1977-1983; DOI: https://doi.org/10.2967/jnumed.116.187625
Steven Deleye
1Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium
Ann-Marie Waldron
1Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium
Jeroen Verhaeghe
1Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium
Astrid Bottelbergs
2Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium
Leonie Wyffels
1Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium
3Nuclear Medicine Department, University Hospital Antwerp, Antwerp, Belgium; and
Bianca Van Broeck
2Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium
Xavier Langlois
4Foundational Neuroscience Center, Abbvie, Cambridge, Massachusetts
Mark Schmidt
2Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium
Sigrid Stroobants
3Nuclear Medicine Department, University Hospital Antwerp, Antwerp, Belgium; and
Steven Staelens
1Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium
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Journal of Nuclear Medicine
Vol. 58, Issue 12
December 1, 2017
Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease
Steven Deleye, Ann-Marie Waldron, Jeroen Verhaeghe, Astrid Bottelbergs, Leonie Wyffels, Bianca Van Broeck, Xavier Langlois, Mark Schmidt, Sigrid Stroobants, Steven Staelens
Journal of Nuclear Medicine Dec 2017, 58 (12) 1977-1983; DOI: 10.2967/jnumed.116.187625
Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease
Steven Deleye, Ann-Marie Waldron, Jeroen Verhaeghe, Astrid Bottelbergs, Leonie Wyffels, Bianca Van Broeck, Xavier Langlois, Mark Schmidt, Sigrid Stroobants, Steven Staelens
Journal of Nuclear Medicine Dec 2017, 58 (12) 1977-1983; DOI: 10.2967/jnumed.116.187625
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