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Table of Contents

October 1, 2017; Volume 58,Issue 10

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 7A;

Editor’s Page

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    Is 16 Months of Specialized Nuclear Medicine Training Enough for Best Patient Care?
    Johannes Czernin
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1535;

Hot Topics

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    Nuclear Medicine Training: What Now?
    David Mankoff and Daniel A. Pryma
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1536-1538; DOI: https://doi.org/10.2967/jnumed.117.190132

The State of the Art

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    18F-FDG PET/CT in Lymphoma: Has Imaging-Directed Personalized Medicine Become a Reality?
    Sally F. Barrington and Peter W.M. Johnson
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1539-1544; DOI: https://doi.org/10.2967/jnumed.116.181347

Continuing Education

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    PSMA Ligands for PET Imaging of Prostate Cancer
    Sarah M. Schwarzenboeck, Isabel Rauscher, Christina Bluemel, Wolfgang P. Fendler, Steven P. Rowe, Martin G. Pomper, Ali Asfhar-Oromieh, Ken Herrmann and Matthias Eiber
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1545-1552; DOI: https://doi.org/10.2967/jnumed.117.191031

Focus on Molecular Imaging

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    Pretargeted Imaging and Therapy
    Mohamed Altai, Rosemery Membreno, Brendon Cook, Vladimir Tolmachev and Brian M. Zeglis
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1553-1559; DOI: https://doi.org/10.2967/jnumed.117.189944

Oncology

  • Basic

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      Imaging of Programmed Cell Death Ligand 1: Impact of Protein Concentration on Distribution of Anti-PD-L1 SPECT Agents in an Immunocompetent Murine Model of Melanoma
      Jessie R. Nedrow, Anders Josefsson, Sunju Park, Sagar Ranka, Sanchita Roy and George Sgouros
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1560-1566; DOI: https://doi.org/10.2967/jnumed.117.193268
  • Translational

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      18F-Fluoromisonidazole Kinetic Modeling for Characterization of Tumor Perfusion and Hypoxia in Response to Antiangiogenic Therapy
      Milan Grkovski, Sally-Ann Emmas and Sean D. Carlin
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1567-1573; DOI: https://doi.org/10.2967/jnumed.117.190892
  • Clinical

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      In Vivo Relationship Between Hypoxia and Angiogenesis in Human Glioblastoma: A Multimodal Imaging Study
      Keven Ferreira da Ponte, David Hassanein Berro, Solène Collet, Jean-Marc Constans, Evelyne Emery, Samuel Valable and Jean-Sébastien Guillamo
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1574-1579; DOI: https://doi.org/10.2967/jnumed.116.188557
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      Improved Detection of Transosseous Meningiomas Using 68Ga-DOTATATE PET/CT Compared with Contrast-Enhanced MRI
      Wolfgang G. Kunz, Lisa M. Jungblut, Philipp M. Kazmierczak, Franziska J. Vettermann, Andreas Bollenbacher, Jörg C. Tonn, Christian Schichor, Axel Rominger, Nathalie L. Albert, Peter Bartenstein, Maximilian F. Reiser and Clemens C. Cyran
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1580-1587; DOI: https://doi.org/10.2967/jnumed.117.191932
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      Alternative Means of Estimating 131I Maximum Permissible Activity to Treat Thyroid Cancer
      Kenneth J. Nichols, William Robeson, Miyuki Yoshida-Hay, Pat B. Zanzonico, Fritzgerald Leveque, Kuldeep K. Bhargava, Gene G. Tronco and Christopher J. Palestro
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1588-1595; DOI: https://doi.org/10.2967/jnumed.117.192278
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      Reader Training for the Restaging of Biochemically Recurrent Prostate Cancer Using 18F-Fluciclovine PET/CT
      Matthew P. Miller, Lale Kostakoglu, Daniel Pryma, Jian Qin Yu, Albert Chau, Eric Perlman, Bonnie Clarke, Donald Rosen and Penelope Ward
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1596-1602; DOI: https://doi.org/10.2967/jnumed.116.188375
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      Assessing Bone Marrow Activity in Patients with Myelofibrosis: Results of a Pilot Study of 18F-FLT PET
      Laetitia Vercellino, Matthieu John Ouvrier, Emmanuelle Barré, Bruno Cassinat, Virginie de Beco, Christine Dosquet, Sylvie Chevret, Véronique Meignin, Christine Chomienne, Marie-Elisabeth Toubert, Pascal Merlet and Jean-Jacques Kiladjian
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1603-1608; DOI: https://doi.org/10.2967/jnumed.116.188508

Theranostics

  • Basic

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      SSTR-Mediated Imaging in Breast Cancer: Is There a Role for Radiolabeled Somatostatin Receptor Antagonists?
      Simone U. Dalm, Joost Haeck, Gabriela N. Doeswijk, Erik de Blois, Marion de Jong and Carolien H.M. van Deurzen
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1609-1614; DOI: https://doi.org/10.2967/jnumed.116.189035
  • Clinical

    • INVITED PERSPECTIVE

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        Accuracy in the Eye of the Beholder: Can We Improve Agreement in Prostate Cancer Diagnostics with PSMA PET/CT?
        Michael S. Hofman
        Journal of Nuclear Medicine October 1, 2017, 58 (10) 1615-1616; DOI: https://doi.org/10.2967/jnumed.117.192542
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      68Ga-PSMA-11 PET/CT Interobserver Agreement for Prostate Cancer Assessments: An International Multicenter Prospective Study
      Wolfgang Peter Fendler, Jeremie Calais, Martin Allen-Auerbach, Christina Bluemel, Nina Eberhardt, Louise Emmett, Pawan Gupta, Markus Hartenbach, Thomas A. Hope, Shozo Okamoto, Christian Helmut Pfob, Thorsten D. Pöppel, Christoph Rischpler, Sarah Schwarzenböck, Vanessa Stebner, Marcus Unterrainer, Helle D. Zacho, Tobias Maurer, Christian Gratzke, Alexander Crispin, Johannes Czernin, Ken Herrmann and Matthias Eiber
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1617-1623; DOI: https://doi.org/10.2967/jnumed.117.190827
    • FEATURED ARTICLE OF THE MONTH

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        Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding
        Clemens Kratochwil, Frank Bruchertseifer, Hendrik Rathke, Marcus Bronzel, Christos Apostolidis, Wilko Weichert, Uwe Haberkorn, Frederik L. Giesel and Alfred Morgenstern
        Journal of Nuclear Medicine October 1, 2017, 58 (10) 1624-1631; DOI: https://doi.org/10.2967/jnumed.117.191395
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      Exploring New Multimodal Quantitative Imaging Indices for the Assessment of Osseous Tumor Burden in Prostate Cancer Using 68Ga-PSMA PET/CT
      Marie Bieth, Markus Krönke, Robert Tauber, Marielena Dahlbender, Margitta Retz, Stephan G. Nekolla, Bjoern Menze, Tobias Maurer, Matthias Eiber and Markus Schwaiger
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1632-1637; DOI: https://doi.org/10.2967/jnumed.116.189050

Cardiology

  • Translational

    • FEATURED TRANSLATIONAL SCIENCE ARTICLE

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        Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: A Translational 18F-FDG PET/CT Observation
        Matteo Bauckneht, Giulia Ferrarazzo, Francesco Fiz, Silvia Morbelli, Matteo Sarocchi, Fabio Pastorino, Alberto Ghidella, Elena Pomposelli, Maurizio Miglino, Pietro Ameri, Laura Emionite, Flavia Ticconi, Eleonora Arboscello, Ambra Buschiazzo, Elena Augusta Massimelli, Salvatore Fiordoro, Anna Borra, Vanessa Cossu, Annalisa Bozzano, Adalberto Ibatici, Mirco Ponzoni, Paolo Spallarossa, Andrea Gallamini, Paolo Bruzzi, Gianmario Sambuceti and Cecilia Marini
        Journal of Nuclear Medicine October 1, 2017, 58 (10) 1638-1645; DOI: https://doi.org/10.2967/jnumed.117.191122

Neurology

  • Translational

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      Evaluation of the Effect of Fingolimod Treatment on Microglial Activation Using Serial PET Imaging in Multiple Sclerosis
      Marcus Sucksdorff, Eero Rissanen, Jouni Tuisku, Salla Nuutinen, Teemu Paavilainen, Johanna Rokka, Juha Rinne and Laura Airas
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1646-1651; DOI: https://doi.org/10.2967/jnumed.116.183020

Molecular Imaging

  • Basic

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      High-Contrast PET Imaging of Vasopressin V1B Receptors with a Novel Radioligand, 11C-TASP699
      Kazumi Koga, Yuji Nagai, Masayuki Hanyu, Mitsukane Yoshinaga, Shigeyuki Chaki, Norikazu Ohtake, Satoshi Ozaki, Ming-Rong Zhang, Tetsuya Suhara and Makoto Higuchi
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1652-1658; DOI: https://doi.org/10.2967/jnumed.116.188698
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      Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease–Mediated Genome Editing
      Esther Wolfs, Bryan Holvoet, Laura Ordovas, Natacha Breuls, Nicky Helsen, Matthias Schönberger, Susanna Raitano, Tom Struys, Bert Vanbilloen, Cindy Casteels, Maurilio Sampaolesi, Koen Van Laere, Ivo Lambrichts, Catherine M. Verfaillie and Christophe M. Deroose
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1659-1665; DOI: https://doi.org/10.2967/jnumed.117.189779
  • Clinical

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      18F-Tetrafluoroborate, a PET Probe for Imaging Sodium/Iodide Symporter Expression: Whole-Body Biodistribution, Safety, and Radiation Dosimetry in Thyroid Cancer Patients
      Jim O’Doherty, Maite Jauregui-Osoro, Teresa Brothwood, Teresa Szyszko, Paul K. Marsden, Michael J. O’Doherty, Gary J.R. Cook, Philip J. Blower and Val Lewington
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1666-1671; DOI: https://doi.org/10.2967/jnumed.117.192252

Radiation Biology

  • Clinical

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      Three-Dimensional Dosimetry for Radiation Safety Estimates from Intrathecal Administration
      Jacob Y. Hesterman, Susan D. Kost, Robert W. Holt, Howard Dobson, Ajay Verma and P. David Mozley
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1672-1678; DOI: https://doi.org/10.2967/jnumed.117.190611

Imaging/Infection

  • Basic

    • FEATURED BASIC SCIENCE ARTICLE

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        Specific Imaging of Bacterial Infection Using 6″-18F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria
        Gayatri Gowrishankar, Jonathan Hardy, Mirwais Wardak, Mohammad Namavari, Robert E. Reeves, Evgenios Neofytou, Ananth Srinivasan, Joseph C. Wu, Christopher H. Contag and Sanjiv Sam Gambhir
        Journal of Nuclear Medicine October 1, 2017, 58 (10) 1679-1684; DOI: https://doi.org/10.2967/jnumed.117.191452
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      Imaging Macrophage Accumulation in a Murine Model of Chronic Pancreatitis with 125I-Iodo-DPA-713 SPECT/CT
      Catherine A. Foss, Liansheng Liu, Ronnie C. Mease, Haofan Wang, Pankaj Pasricha and Martin G. Pomper
      Journal of Nuclear Medicine October 1, 2017, 58 (10) 1685-1690; DOI: https://doi.org/10.2967/jnumed.117.189571

Physics/Instrumentation

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    Quantitative Evaluation of 2 Scatter-Correction Techniques for 18F-FDG Brain PET/MRI in Regard to MR-Based Attenuation Correction
    Jarmo Teuho, Virva Saunavaara, Tuula Tolvanen, Terhi Tuokkola, Antti Karlsson, Jouni Tuisku and Mika Teräs
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1691-1698; DOI: https://doi.org/10.2967/jnumed.117.190231
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    Simulation of Tracer Dose Reduction in 18F-FDG PET/MRI: Effects on Oncologic Reading, Image Quality, and Artifacts
    Ferdinand Seith, Holger Schmidt, Julia Kunz, Thomas Küstner, Sergios Gatidis, Konstantin Nikolaou, Christian la Fougère and Nina Schwenzer
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1699-1705; DOI: https://doi.org/10.2967/jnumed.116.184440

Letters to the Editor

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    Dual-Integrin αvβ3- and Gastrin-Releasing Peptide Receptor–Targeting PET Radiotracer (68Ga-BBN-RGD)
    Andrei Iagaru
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1706; DOI: https://doi.org/10.2967/jnumed.117.191478
  • You have access
    Reply: Dual-Integrin αvβ3- and Gastrin-Releasing Peptide Receptor–Targeting PET Radiotracer (68Ga-BBN-RGD)
    Xiaoyuan Chen
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1706-1707; DOI: https://doi.org/10.2967/jnumed.117.198374

Errata

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    Errata
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 1707;

SNMMI Newsline

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    2017 SNMMI Highlights Lecture: Neuroscience
    Alexander Drzezga
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 9N-15N;
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    SNMMI Honors Contributors at 2017 Annual Meeting
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 17N-18N;
  • You have access
    Radioiodine Theranostics: Increasing Dialogue and Collaboration
    Douglas Van Nostrand
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 19N-20N;
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    SNMMI Leadership Update: SNMMI 2018 Mid-Winter Symposium in Orlando: Focus on Theranostics
    Virginia Pappas
    Journal of Nuclear Medicine October 1, 2017, 58 (10) 21N;
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In this issue

Journal of Nuclear Medicine: 58 (10)
Journal of Nuclear Medicine
Vol. 58, Issue 10
October 1, 2017
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding
  • Specific Imaging of Bacterial Infection Using 6″-18F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria
  • Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: A Translational 18F-FDG PET/CT Observation
  • 18F-FDG PET/CT in Lymphoma: Has Imaging-Directed Personalized Medicine Become a Reality?
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      • INVITED PERSPECTIVE
      • FEATURED ARTICLE OF THE MONTH
  • Cardiology
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      • FEATURED TRANSLATIONAL SCIENCE ARTICLE
  • Neurology
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  • Initial Clinical Experience with 90Y-FAPI-46 Radioligand Therapy for Advanced-Stage Solid Tumors: A Case Series of 9 Patients
  • Total-Body PET Multiparametric Imaging of Cancer Using a Voxelwise Strategy of Compartmental Modeling
  • Prospective phase 2 trial of PSMA-targeted molecular RadiothErapy with 177Lu-PSMA-617 for metastatic castration-reSISTant Prostate Cancer (RESIST-PC): efficacy results of the UCLA cohort
  • Why We Did What We Did: PSMA PET/CT Selection Criteria for the VISION Trial
  • 68Ga-FAPI as a Diagnostic Tool in Sarcoma: Data from the 68Ga-FAPI PET Prospective Observational Trial
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