Research ArticleNeurology
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates
Nicolas Tournier, Sebastien Goutal, Sylvain Auvity, Alexander Traxl, Severin Mairinger, Thomas Wanek, Ourkia-Badia Helal, Irène Buvat, Michael Soussan, Fabien Caillé and Oliver Langer
Journal of Nuclear Medicine January 2017, 58 (1) 117-122; DOI: https://doi.org/10.2967/jnumed.116.178665
Nicolas Tournier
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Sebastien Goutal
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Sylvain Auvity
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Alexander Traxl
2Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria
Severin Mairinger
2Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria
Thomas Wanek
2Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria
Ourkia-Badia Helal
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Irène Buvat
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Michael Soussan
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Fabien Caillé
1Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France
Oliver Langer
2Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria
3Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria; and
4Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria
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Journal of Nuclear Medicine
Vol. 58, Issue 1
January 1, 2017
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates
Nicolas Tournier, Sebastien Goutal, Sylvain Auvity, Alexander Traxl, Severin Mairinger, Thomas Wanek, Ourkia-Badia Helal, Irène Buvat, Michael Soussan, Fabien Caillé, Oliver Langer
Journal of Nuclear Medicine Jan 2017, 58 (1) 117-122; DOI: 10.2967/jnumed.116.178665
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates
Nicolas Tournier, Sebastien Goutal, Sylvain Auvity, Alexander Traxl, Severin Mairinger, Thomas Wanek, Ourkia-Badia Helal, Irène Buvat, Michael Soussan, Fabien Caillé, Oliver Langer
Journal of Nuclear Medicine Jan 2017, 58 (1) 117-122; DOI: 10.2967/jnumed.116.178665
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