Chinese data of efficacy of low- and high-dose of iodine-131 for the ablation of thyroid remnant

Article Figures & Data


	1850 MBq n=155	3700 MBq n=123	t/Ï‡²	P
Age-yr	44±13	45±13	-0.716	0.475
Female sex-no. (%)	112 (72.3%)	87 (70.7%)	0.079	0.790
Time from thyroidectomy to thyroid ablation-days	53±30	55±36	-0.565	0.572
Type of thyroidectomy-no. (%)
Total thyroidectomy	145 (93.5%)	109 (88.6%)
Near total thyroidectomy	10 (6.5%)	14 (11.4%)	2.114	0.197
Histology-no. (%)
Papillary	151 (97.4%)	117 (95.1%)
Follicular	3 (1.9%)	4 (3.3%)
Mix	1 (0.6%)	2 (1.6%)	1.121	.591
Tumor size (cm)	1.46±1.52	1.39±0.98	0.422	0.673
Multifocal cancer-no. (%)
Yes	87 (56.1%)	62 (50.4%)
No	64 (41.3%)	57 (46.3%)
Unknown	4 (2.6%)	4 (3.3%)	0.928	0.629
T Stage-no. (%)
T1	94 (60.6%)	77 (62.6%)
T2	19 (12.3%)	12 (9.8%)
T3	28 (18.1%)	21 (17.1%)
Tx (Unknown size)	14 (9.0%)	13 (10.6%)	3.143	0.556
Lymph node metastasis-no. (%)
N0	48 (30.9%)	36 (29.3%)
N1a	66 (42.6%)	54 (43.9%)
N1b	41(26.5%)	33 (26.8%)	0.851	0.993
Serum Tg (ng/ml)	10.04±19.80	12.84±24.82	-1.046	0.296
TSH (uIU/ml)	70.67±34.95	65.80±32.76	1.186	0.237
¹³¹I-WBS-no. (%)
Stage I	5 (3.2%)	5 (4.1%)
Stage II	41 (26.5%)	22 (17.9%)
Stage III	109 (70.3%)	96 (78.0%)	2.910	0.244
Positive Anti-Tg Ab-no. (%)	34 (22.1%)	36 (29.3%)	1.872	0.210
Residence place-no. (%)
Coastal areas	136 (87.7%)	110 (89.4%)
Non-coastal areas	19 (12.3%)	13 (10.6%)	0.192	0.709


	Odds of success vs unsuccessful ablation for the first value proportionate to the second value
Independent predicting factors	P values	OR	95% CI for OR
Predictors of first-dose successful ablation
Age	0.022	1.040	1.006-1.075
TgAb-off	0.020	2.651	1.164-6.040
The factors not associated with treatment response
Dose of administered ¹³¹I: 1850 vs. 3700 (MBq)	0.465	0.724	0.304-1.723
Sex: female vs. male	0.291	1.812	0.300-5.471
Residence:	0.838	0.874	0.240-3.183
Interval	0.684	0.636	0.072-5.601
Size	0.409	1.232	0.751-2.021
LNM: Yes or not	0.100	0.353	0.103-1.218
Baseline serum Tg	0.252	0.983	0.955-1.012
Baseline serum TSH	0.901	1.001	0.988-1.014
Type of thyroidectomy: TT vs. NTT	0.726	0757	0.160-3.579