Research ArticleBasic Science Investigations
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme
Laigao Chen, Nabeel Nabulsi, Mika Naganawa, Kenneth Zasadny, Marc B. Skaddan, Lei Zhang, Soheila Najafzadeh, Shu-fei Lin, Christopher J. Helal, Tracey L. Boyden, Cheng Chang, Jim Ropchan, Richard E. Carson, Anabella Villalobos and Yiyun Huang
Journal of Nuclear Medicine September 2016, 57 (9) 1448-1453; DOI: https://doi.org/10.2967/jnumed.115.171454
Laigao Chen
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Nabeel Nabulsi
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Mika Naganawa
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Kenneth Zasadny
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Marc B. Skaddan
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Lei Zhang
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Soheila Najafzadeh
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Shu-fei Lin
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Christopher J. Helal
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Tracey L. Boyden
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Cheng Chang
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Jim Ropchan
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Richard E. Carson
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
Anabella Villalobos
1Pfizer Worldwide Research and Development, Groton, Connecticut; and
Yiyun Huang
2PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut
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Journal of Nuclear Medicine
Vol. 57, Issue 9
September 1, 2016
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme
Laigao Chen, Nabeel Nabulsi, Mika Naganawa, Kenneth Zasadny, Marc B. Skaddan, Lei Zhang, Soheila Najafzadeh, Shu-fei Lin, Christopher J. Helal, Tracey L. Boyden, Cheng Chang, Jim Ropchan, Richard E. Carson, Anabella Villalobos, Yiyun Huang
Journal of Nuclear Medicine Sep 2016, 57 (9) 1448-1453; DOI: 10.2967/jnumed.115.171454
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme
Laigao Chen, Nabeel Nabulsi, Mika Naganawa, Kenneth Zasadny, Marc B. Skaddan, Lei Zhang, Soheila Najafzadeh, Shu-fei Lin, Christopher J. Helal, Tracey L. Boyden, Cheng Chang, Jim Ropchan, Richard E. Carson, Anabella Villalobos, Yiyun Huang
Journal of Nuclear Medicine Sep 2016, 57 (9) 1448-1453; DOI: 10.2967/jnumed.115.171454