Research ArticleClinical Investigations
First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430
Mika Naganawa, Rikki N. Waterhouse, Nabeel Nabulsi, Shu-Fei Lin, David Labaree, Jim Ropchan, Sanela Tarabar, Nicholas DeMartinis, Adam Ogden, Anindita Banerjee, Yiyun Huang and Richard E. Carson
Journal of Nuclear Medicine September 2016, 57 (9) 1388-1395; DOI: https://doi.org/10.2967/jnumed.115.166850
Mika Naganawa
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Rikki N. Waterhouse
2Pfizer Worldwide Research and Development, Cambridge, Massachusetts
Nabeel Nabulsi
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Shu-Fei Lin
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
David Labaree
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Jim Ropchan
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Sanela Tarabar
2Pfizer Worldwide Research and Development, Cambridge, Massachusetts
Nicholas DeMartinis
2Pfizer Worldwide Research and Development, Cambridge, Massachusetts
Adam Ogden
2Pfizer Worldwide Research and Development, Cambridge, Massachusetts
Anindita Banerjee
2Pfizer Worldwide Research and Development, Cambridge, Massachusetts
Yiyun Huang
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Richard E. Carson
1Department of Radiology and Biomedical Imaging, PET Center, Yale School of Medicine, New Haven, Connecticut; and
Data supplements
Supplemental Data
Files in this Data Supplement:
In this issue
Journal of Nuclear Medicine
Vol. 57, Issue 9
September 1, 2016
First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430
Mika Naganawa, Rikki N. Waterhouse, Nabeel Nabulsi, Shu-Fei Lin, David Labaree, Jim Ropchan, Sanela Tarabar, Nicholas DeMartinis, Adam Ogden, Anindita Banerjee, Yiyun Huang, Richard E. Carson
Journal of Nuclear Medicine Sep 2016, 57 (9) 1388-1395; DOI: 10.2967/jnumed.115.166850
First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430
Mika Naganawa, Rikki N. Waterhouse, Nabeel Nabulsi, Shu-Fei Lin, David Labaree, Jim Ropchan, Sanela Tarabar, Nicholas DeMartinis, Adam Ogden, Anindita Banerjee, Yiyun Huang, Richard E. Carson
Journal of Nuclear Medicine Sep 2016, 57 (9) 1388-1395; DOI: 10.2967/jnumed.115.166850
Jump to section
Related Articles
Cited By...
- Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain
- Target Engagement of a Phosphodiesterase 2A Inhibitor Affecting Long-Term Memory in the Rat
- Imaging the Enzyme 11{beta}-Hydroxysteroid Dehydrogenase Type 1 with PET: Evaluation of the Novel Radiotracer 11C-AS2471907 in Human Brain
- Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand 11C-BMT-136088 for Lung Imaging in Rhesus Monkeys
- Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme