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Journal of Nuclear Medicine

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Table of Contents

April 1, 2015; Volume 56,Issue 4

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 8A;

SNMMI Newsline

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    Canadian NRU Extended; Medical Isotope Partnership Announced
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 9N;
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    NIH Partnership Launches Big Data Portal for AD Drug Discovery
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 10N;
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    History Corner: From the New SNMMI Historian
    Frederic Fahey
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 11N;
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    AMA, 99 Other Groups Call for ICD-10 Transition Contingencies
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 12N;
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    Lenvatinib Receives Approval in DTC
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 12N;
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    SNMMI Leadership Update: SNMMI Annual Meeting Heads to Baltimore
    Virginia Pappas
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 13N;
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    Newsbriefs
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 14N-15N;
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    From the Literature
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 16N-20N;

Focus on Molecular Imaging

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    The Role of Exploratory Investigational New Drugs for Translating Radiopharmaceuticals into First-in-Human Studies
    Sally W. Schwarz and Reiko Oyama
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 497-500; DOI: https://doi.org/10.2967/jnumed.114.146472

Invited Perspectives

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    γ-H2AX Foci in Peripheral Blood Lymphocytes to Quantify Radiation-Induced DNA Damage After 177Lu-DOTA-Octreotate Peptide Receptor Radionuclide Therapy
    Johan Bussink and Paul N. Span
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 501-502; DOI: https://doi.org/10.2967/jnumed.115.153841
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    PET Assessment of Vascular Inflammation and Atherosclerotic Plaques: SUV or TBR?
    Wengen Chen and Vasken Dilsizian
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 503-504; DOI: https://doi.org/10.2967/jnumed.115.154385

Clinical Investigations

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    Analysis of 177Lu-DOTA-Octreotate Therapy–Induced DNA Damage in Peripheral Blood Lymphocytes of Patients with Neuroendocrine Tumors
    Delphine Denoyer, Pavel Lobachevsky, Price Jackson, Mick Thompson, Olga A. Martin and Rodney J. Hicks
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 505-511; DOI: https://doi.org/10.2967/jnumed.114.145581
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    The 18-kDa Mitochondrial Translocator Protein in Human Gliomas: An 11C-(R)PK11195 PET Imaging and Neuropathology Study
    Zhangjie Su, Federico Roncaroli, Pascal F. Durrenberger, David J. Coope, Konstantina Karabatsou, Rainer Hinz, Gerard Thompson, Federico E. Turkheimer, Karolina Janczar, Daniel Du Plessis, Andrew Brodbelt, Alan Jackson, Alexander Gerhard and Karl Herholz
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 512-517; DOI: https://doi.org/10.2967/jnumed.114.151621
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    Metabolic PET/CT-Guided Lung Lesion Biopsies: Impact on Diagnostic Accuracy and Rate of Sampling Error
    Ludmila Guralnik, Radu Rozenberg, Alex Frenkel, Ora Israel and Zohar Keidar
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 518-522; DOI: https://doi.org/10.2967/jnumed.113.131466
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    Improving Patient Selection for 18F-FDG PET Scanning in the Staging of Gastric Cancer
    Yui Kaneko, William K Murray, Emma Link, Rodney J. Hicks and Cuong Duong
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 523-529; DOI: https://doi.org/10.2967/jnumed.114.150946
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    PET Response Criteria in Solid Tumors Predicts Progression-Free Survival and Time to Local or Distant Progression After Chemotherapy with Regional Hyperthermia for Soft-Tissue Sarcoma
    Wolfgang P. Fendler, Mona Lehmann, Andrei Todica, Ken Herrmann, Thomas Knösel, Martin K. Angele, Hans Roland Dürr, Josefine Rauch, Peter Bartenstein, Clemens C. Cyran, Marcus Hacker and Lars H. Lindner
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 530-537; DOI: https://doi.org/10.2967/jnumed.114.152462
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    Feasibility of In Situ, High-Resolution Correlation of Tracer Uptake with Histopathology by Quantitative Autoradiography of Biopsy Specimens Obtained Under 18F-FDG PET/CT Guidance
    Louise M. Fanchon, Snjezana Dogan, Andre L. Moreira, Sean A. Carlin, C. Ross Schmidtlein, Ellen Yorke, Aditya P. Apte, Irene A. Burger, Jeremy C. Durack, Joseph P. Erinjeri, Majid Maybody, Heiko Schöder, Robert H. Siegelbaum, Constantinos T. Sofocleous, Joseph O. Deasy, Stephen B. Solomon, John L. Humm and Assen S. Kirov
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 538-544; DOI: https://doi.org/10.2967/jnumed.114.148668
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    Radiation Dose and Prognosis of Ultra-Low-Dose Stress-First Myocardial Perfusion SPECT in Patients with Chest Pain Using a High-Efficiency Camera
    Andrew J. Einstein, Lynne L. Johnson, Albert J. DeLuca, Andrew C. Kontak, Daniel W. Groves, Jennifer Stant, Ted Pozniakoff, Bin Cheng, LeRoy E. Rabbani and Sabahat Bokhari
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 545-551; DOI: https://doi.org/10.2967/jnumed.114.150664
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    Variability and Uncertainty of 18F-FDG PET Imaging Protocols for Assessing Inflammation in Atherosclerosis: Suggestions for Improvement
    Pauline Huet, Samuel Burg, Dominique Le Guludec, Fabien Hyafil and Irène Buvat
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 552-559; DOI: https://doi.org/10.2967/jnumed.114.142596
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    Improved Power for Characterizing Longitudinal Amyloid-β PET Changes and Evaluating Amyloid-Modifying Treatments with a Cerebral White Matter Reference Region
    Kewei Chen, Auttawut Roontiva, Pradeep Thiyyagura, Wendy Lee, Xiaofen Liu, Napatkamon Ayutyanont, Hillary Protas, Ji.Luo Luo, Robert Bauer, Cole Reschke, Daniel Bandy, Robert A. Koeppe, Adam S. Fleisher, Richard J. Caselli, Susan Landau, William J. Jagust, Michael W. Weiner and Eric M. Reiman
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 560-566; DOI: https://doi.org/10.2967/jnumed.114.149732
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    Measurement of Longitudinal β-Amyloid Change with 18F-Florbetapir PET and Standardized Uptake Value Ratios
    Susan M. Landau, Allison Fero, Suzanne L. Baker, Robert Koeppe, Mark Mintun, Kewei Chen, Eric M. Reiman and William J. Jagust
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 567-574; DOI: https://doi.org/10.2967/jnumed.114.148981
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    Establishing Age-Associated Normative Ranges of the Cerebral 18F-FDG Uptake Ratio in Children
    Chiaho Hua, Thomas E. Merchant, Xingyu Li, Yimei Li and Barry L. Shulkin
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 575-579; DOI: https://doi.org/10.2967/jnumed.114.146993
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    Aromatase Imaging with [N-Methyl-11C]Vorozole PET in Healthy Men and Women
    Anat Biegon, David L. Alexoff, Sung Won Kim, Jean Logan, Deborah Pareto, David Schlyer, Gene-Jack Wang and Joanna S. Fowler
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 580-585; DOI: https://doi.org/10.2967/jnumed.114.150383
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    Characterization in Humans of 18F-MNI-444, a PET Radiotracer for Brain Adenosine 2A Receptors
    Olivier Barret, Jonas Hannestad, Christine Vala, David Alagille, Adriana Tavares, Marc Laruelle, Danna Jennings, Ken Marek, David Russell, John Seibyl and Gilles Tamagnan
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 586-591; DOI: https://doi.org/10.2967/jnumed.114.152546

Continuing Education

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    Approaches to Reducing Radiation Dose from Radionuclide Myocardial Perfusion Imaging
    Sharmila Dorbala, Ron Blankstein, Hicham Skali, Mi-Ae Park, Jolene Fantony, Charles Mauceri, James Semer, Stephen C. Moore and Marcelo F. Di Carli
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 592-599; DOI: https://doi.org/10.2967/jnumed.112.115097

Basic Science Investigations

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    Mesenchymal Stem Cell–Mediated, Tumor Stroma–Targeted Radioiodine Therapy of Metastatic Colon Cancer Using the Sodium Iodide Symporter as Theranostic Gene
    Kerstin Knoop, Nathalie Schwenk, Kathrin Schmohl, Andrea Müller, Christian Zach, Clemens Cyran, Janette Carlsen, Guido Böning, Peter Bartenstein, Burkhard Göke, Ernst Wagner, Peter J. Nelson and Christine Spitzweg
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 600-606; DOI: https://doi.org/10.2967/jnumed.114.146662
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    The Reverse Warburg Effect and 18F-FDG Uptake in Non–Small Cell Lung Cancer A549 in Mice: A Pilot Study
    Guojian Zhang, Jianbo Li, Xuemei Wang, Yuanyuan Ma, Xindao Yin, Feng Wang, Huaiyu Zheng, Xiaoxian Duan, Gregory C. Postel and Xiao-Feng Li
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 607-612; DOI: https://doi.org/10.2967/jnumed.114.148254
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    Triple-Peptide Receptor Targeting In Vitro Allows Detection of All Tested Gut and Bronchial NETs
    Jean Claude Reubi and Beatrice Waser
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 613-615; DOI: https://doi.org/10.2967/jnumed.114.153189
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    PET Imaging of Tenascin-C with a Radiolabeled Single-Stranded DNA Aptamer
    Orit Jacobson, Xuefeng Yan, Gang Niu, Ido D. Weiss, Ying Ma, Lawrence P. Szajek, Baozhong Shen, Dale O. Kiesewetter and Xiaoyuan Chen
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 616-621; DOI: https://doi.org/10.2967/jnumed.114.149484
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    Comparative Studies of Three 68Ga-Labeled [Des-Arg10]Kallidin Derivatives for Imaging Bradykinin B1 Receptor Expression with PET
    Kuo-Shyan Lin, Guillaume Amouroux, Jinhe Pan, Zhengxing Zhang, Silvia Jenni, Joseph Lau, Zhibo Liu, Navjit Hundal-Jabal, Nadine Colpo and François Bénard
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 622-627; DOI: https://doi.org/10.2967/jnumed.114.152132
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    Preclinical Evaluation of 86Y-Labeled Inhibitors of Prostate-Specific Membrane Antigen for Dosimetry Estimates
    Sangeeta Ray Banerjee, Catherine A. Foss, Mrudula Pullambhatla, Yuchuan Wang, Senthamizhchelvan Srinivasan, Robert F. Hobbs, Kwamena E. Baidoo, Martin W. Brechbiel, Sridhar Nimmagadda, Ronnie C. Mease, George Sgouros and Martin G. Pomper
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 628-634; DOI: https://doi.org/10.2967/jnumed.114.149062
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    Impact of Time-of-Flight PET on Quantification Errors in MR Imaging–Based Attenuation Correction
    Abolfazl Mehranian and Habib Zaidi
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 635-641; DOI: https://doi.org/10.2967/jnumed.114.148817

Special Contributions

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    American College of Radiology and Society of Nuclear Medicine and Molecular Imaging Joint Credentialing Statement for PET/MR Imaging: Brain
    Hossein Jadvar, Rathan M. Subramaniam, Claudia G. Berman, Fernando Boada, Patrick M. Colletti, Alexander R. Guimaraes, Jonathan McConathy, Carolyn C. Meltzer, Richard B. Noto, Alan B. Packard, Eric M. Rohren and M. Elizabeth Oates
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 642-645; DOI: https://doi.org/10.2967/jnumed.115.155218
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    Standardization of Administered Activities in Pediatric Nuclear Medicine: A Report of the First Nuclear Medicine Global Initiative Project, Part 1—Statement of the Issue and a Review of Available Resources
    Frederic H. Fahey, Henry Hee-Seong Bom, Arturo Chiti, Yun Young Choi, Gang Huang, Michael Lassmann, Norman Laurin, Fernando Mut, Rodolfo Nuñez-Miller, Darin O’Keeffe, Prasanta Pradhan, Andrew M. Scott, Shaoli Song, Nischal Soni, Mayuki Uchiyama and Luis Vargas
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 646-651; DOI: https://doi.org/10.2967/jnumed.114.152249

Book Reviews

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    Imaging in Clinical Oncology
    E. Edmund Kim
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 652; DOI: https://doi.org/10.2967/jnumed.115.155523

Letters to the Editor

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    Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding
    Cameron J. Koch and Sydney M. Evans
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 653; DOI: https://doi.org/10.2967/jnumed.114.151662
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    Reply: Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding
    Satish K. Chitneni, Gerald T. Bida, Michael R. Zalutsky and Mark W. Dewhirst
    Journal of Nuclear Medicine April 1, 2015, 56 (4) 653-654; DOI: https://doi.org/10.2967/jnumed.115.154054
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In this issue

Journal of Nuclear Medicine: 56 (4)
Journal of Nuclear Medicine
Vol. 56, Issue 4
April 1, 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • The Role of Exploratory Investigational New Drugs for Translating Radiopharmaceuticals into First-in-Human Studies
  • Improving Patient Selection for 18F-FDG PET Scanning in the Staging of Gastric Cancer
  • Establishing Age-Associated Normative Ranges of the Cerebral 18F-FDG Uptake Ratio in Children
  • Approaches to Reducing Radiation Dose from Radionuclide Myocardial Perfusion Imaging
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  • Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View
  • Slow but Evident Recovery from Neocortical Dysfunction and Cognitive Impairment in a Series of Chronic COVID-19 Patients
  • Tumor Response to Radiopharmaceutical Therapies: The Knowns and the Unknowns
  • Is FDG maximum standardized uptake value (SUV max) of primary breast cancer can predict axillary lymph node metastasis?
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