Dose-Finding Quantitative 18F-FDG PET Imaging Study with the Oral Pan-AKT Inhibitor GSK2141795 in Patients with Gynecologic Malignancies

Hatice Gungor; Azeem Saleem; Syed Babar; Roberto Dina; Mona A. El-Bahrawy; Ed Curry; Nona Rama; Michele Chen; Emily Pickford; Roshan Agarwal; Sarah Blagden; Sabin Carme; Cristian Salinas; Sam Madison; Elizabeth Krachey; Ademi Santiago-Walker; Deborah A. Smith; Shannon R. Morris; Euan A. Stronach; Hani Gabra

doi:10.2967/jnumed.115.156505

Research ArticleClinical Investigations

Dose-Finding Quantitative ¹⁸F-FDG PET Imaging Study with the Oral Pan-AKT Inhibitor GSK2141795 in Patients with Gynecologic Malignancies

Hatice Gungor, Azeem Saleem, Syed Babar, Roberto Dina, Mona A. El-Bahrawy, Ed Curry, Nona Rama, Michele Chen, Emily Pickford, Roshan Agarwal, Sarah Blagden, Sabin Carme, Cristian Salinas, Sam Madison, Elizabeth Krachey, Ademi Santiago-Walker, Deborah A. Smith, Shannon R. Morris, Euan A. Stronach and Hani Gabra

Journal of Nuclear Medicine December 2015, 56 (12) 1828-1835; DOI: https://doi.org/10.2967/jnumed.115.156505

Hatice Gungor

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Azeem Saleem

2Imanova Centre for Imaging Sciences (formerly GSK Clinical Imaging Centre), Hammersmith Hospital, London, United Kingdom

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Syed Babar

3Department of Radiology, Imperial College Healthcare NHS Trust, London, United Kingdom

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Roberto Dina

4Department of Histopathology, Imperial College London, London, United Kingdom

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Mona A. El-Bahrawy

4Department of Histopathology, Imperial College London, London, United Kingdom

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Ed Curry

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Nona Rama

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Michele Chen

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Emily Pickford

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Roshan Agarwal

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Sarah Blagden

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Sabin Carme

5AVIESAN, Strategic Valorization, Paris, France

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Cristian Salinas

2Imanova Centre for Imaging Sciences (formerly GSK Clinical Imaging Centre), Hammersmith Hospital, London, United Kingdom

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Sam Madison

6GlaxoSmithKline, Collegeville, Pennsylvania and Research Triangle Park, North Carolina; and

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Elizabeth Krachey

6GlaxoSmithKline, Collegeville, Pennsylvania and Research Triangle Park, North Carolina; and

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Ademi Santiago-Walker

6GlaxoSmithKline, Collegeville, Pennsylvania and Research Triangle Park, North Carolina; and

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Deborah A. Smith

6GlaxoSmithKline, Collegeville, Pennsylvania and Research Triangle Park, North Carolina; and

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Shannon R. Morris

7MedImmune, AstraZeneca, Gaithersburg, Maryland

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Euan A. Stronach

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Hani Gabra

1Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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Dose-Finding Quantitative ¹⁸F-FDG PET Imaging Study with the Oral Pan-AKT Inhibitor GSK2141795 in Patients with Gynecologic Malignancies

Journal of Nuclear Medicine Dec 2015, 56 (12) 1828-1835; DOI: 10.2967/jnumed.115.156505

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Dose-Finding Quantitative ¹⁸F-FDG PET Imaging Study with the Oral Pan-AKT Inhibitor GSK2141795 in Patients with Gynecologic Malignancies

Journal of Nuclear Medicine Dec 2015, 56 (12) 1828-1835; DOI: 10.2967/jnumed.115.156505

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Keywords

FDG-PET
GSK2141795
imaging
AKT
ovarian cancer

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