Research ArticleBasic Science Investigations
Radiosynthesis, Photoisomerization, Biodistribution, and Metabolite Analysis of 11C-PBB3 as a Clinically Useful PET Probe for Imaging of Tau Pathology
Hiroki Hashimoto, Kazunori Kawamura, Nobuyuki Igarashi, Makoto Takei, Tomoya Fujishiro, Yoshiharu Aihara, Satoshi Shiomi, Masatoshi Muto, Takehito Ito, Kenji Furutsuka, Tomoteru Yamasaki, Joji Yui, Lin Xie, Maiko Ono, Akiko Hatori, Kazuyoshi Nemoto, Tetsuya Suhara, Makoto Higuchi and Ming-Rong Zhang
Journal of Nuclear Medicine September 2014, 55 (9) 1532-1538; DOI: https://doi.org/10.2967/jnumed.114.139550
Hiroki Hashimoto
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Kazunori Kawamura
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Nobuyuki Igarashi
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Makoto Takei
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Tomoya Fujishiro
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Yoshiharu Aihara
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Satoshi Shiomi
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Masatoshi Muto
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
2Tokyo Nuclear Services Co., Ltd., Tokyo, Japan; and
Takehito Ito
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
3SHI Accelerator Service Ltd., Tokyo, Japan
Kenji Furutsuka
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
3SHI Accelerator Service Ltd., Tokyo, Japan
Tomoteru Yamasaki
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Joji Yui
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Lin Xie
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Maiko Ono
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Akiko Hatori
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Kazuyoshi Nemoto
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Tetsuya Suhara
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Makoto Higuchi
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Ming-Rong Zhang
1Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
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In this issue
Journal of Nuclear Medicine
Vol. 55, Issue 9
September 1, 2014
Radiosynthesis, Photoisomerization, Biodistribution, and Metabolite Analysis of 11C-PBB3 as a Clinically Useful PET Probe for Imaging of Tau Pathology
Hiroki Hashimoto, Kazunori Kawamura, Nobuyuki Igarashi, Makoto Takei, Tomoya Fujishiro, Yoshiharu Aihara, Satoshi Shiomi, Masatoshi Muto, Takehito Ito, Kenji Furutsuka, Tomoteru Yamasaki, Joji Yui, Lin Xie, Maiko Ono, Akiko Hatori, Kazuyoshi Nemoto, Tetsuya Suhara, Makoto Higuchi, Ming-Rong Zhang
Journal of Nuclear Medicine Sep 2014, 55 (9) 1532-1538; DOI: 10.2967/jnumed.114.139550
Radiosynthesis, Photoisomerization, Biodistribution, and Metabolite Analysis of 11C-PBB3 as a Clinically Useful PET Probe for Imaging of Tau Pathology
Hiroki Hashimoto, Kazunori Kawamura, Nobuyuki Igarashi, Makoto Takei, Tomoya Fujishiro, Yoshiharu Aihara, Satoshi Shiomi, Masatoshi Muto, Takehito Ito, Kenji Furutsuka, Tomoteru Yamasaki, Joji Yui, Lin Xie, Maiko Ono, Akiko Hatori, Kazuyoshi Nemoto, Tetsuya Suhara, Makoto Higuchi, Ming-Rong Zhang
Journal of Nuclear Medicine Sep 2014, 55 (9) 1532-1538; DOI: 10.2967/jnumed.114.139550
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