Research ArticleBasic Science Investigations
An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of 11C-LY2459989
Ming-Qiang Zheng, Su Jin Kim, Daniel Holden, Shu-fei Lin, Anne Need, Karen Rash, Vanessa Barth, Charles Mitch, Antonio Navarro, Michael Kapinos, Kathleen Maloney, Jim Ropchan, Richard E. Carson and Yiyun Huang
Journal of Nuclear Medicine July 2014, 55 (7) 1185-1191; DOI: https://doi.org/10.2967/jnumed.114.138701
Ming-Qiang Zheng
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Su Jin Kim
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Daniel Holden
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Shu-fei Lin
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Anne Need
2Eli Lilly & Company, Indianapolis, Indiana
Karen Rash
2Eli Lilly & Company, Indianapolis, Indiana
Vanessa Barth
2Eli Lilly & Company, Indianapolis, Indiana
Charles Mitch
2Eli Lilly & Company, Indianapolis, Indiana
Antonio Navarro
2Eli Lilly & Company, Indianapolis, Indiana
Michael Kapinos
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Kathleen Maloney
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Jim Ropchan
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Richard E. Carson
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
Yiyun Huang
1PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut; and
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Journal of Nuclear Medicine
Vol. 55, Issue 7
July 1, 2014
An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of 11C-LY2459989
Ming-Qiang Zheng, Su Jin Kim, Daniel Holden, Shu-fei Lin, Anne Need, Karen Rash, Vanessa Barth, Charles Mitch, Antonio Navarro, Michael Kapinos, Kathleen Maloney, Jim Ropchan, Richard E. Carson, Yiyun Huang
Journal of Nuclear Medicine Jul 2014, 55 (7) 1185-1191; DOI: 10.2967/jnumed.114.138701
An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of 11C-LY2459989
Ming-Qiang Zheng, Su Jin Kim, Daniel Holden, Shu-fei Lin, Anne Need, Karen Rash, Vanessa Barth, Charles Mitch, Antonio Navarro, Michael Kapinos, Kathleen Maloney, Jim Ropchan, Richard E. Carson, Yiyun Huang
Journal of Nuclear Medicine Jul 2014, 55 (7) 1185-1191; DOI: 10.2967/jnumed.114.138701