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Research ArticleClinical Investigations

Transient Ischemic Dilation of the Left Ventricle on SPECT: Correlation with Findings at Coronary CT Angiography

William T. Halligan, Pamela B. Morris, U. Joseph Schoepf, Blaine T. Mischen, James V. Spearman, J. Reid Spears, Philipp Blanke, Young Jun Cho, Justin R. Silverman, Salvatore A. Chiaramida and Ullrich Ebersberger
Journal of Nuclear Medicine June 2014, 55 (6) 917-922; DOI: https://doi.org/10.2967/jnumed.113.125880
William T. Halligan
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Pamela B. Morris
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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U. Joseph Schoepf
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Blaine T. Mischen
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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James V. Spearman
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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J. Reid Spears
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Philipp Blanke
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Young Jun Cho
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
2Department of Radiology, Konyang University College of Medicine, Daejeon, Korea; and
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Justin R. Silverman
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Salvatore A. Chiaramida
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
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Ullrich Ebersberger
1Heart and Vascular Center, Medical University of South Carolina, Charleston, South Carolina
3Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany
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  • FIGURE 1.
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    FIGURE 1.

    Prevalence of coronary artery plaques and significant stenosis. Prevalence of coronary artery plaque and significant stenosis found on cCTA in TID-positive and -negative patients in setting of both normal and pathologic myocardial perfusion on SPECT.

  • FIGURE 2.
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    FIGURE 2.

    cCTA and SPECT in TID-positive/normal perfusion patient. A 54-y-old woman with exclusion of CAD at cCTA (A) and normal myocardial perfusion on SPECT imaging (B). GRst = (ECG)-gated rest study; GStr = (ECG)-gated stress study; SA = short axis.

  • FIGURE 3.
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    FIGURE 3.

    cCTA and SPECT in TID-positive/pathologic perfusion patient. (A) A 68-y-old man with significant coronary artery stenosis of proximal and mid portion of left anterior descending artery (arrows). (B) SPECT imaging revealed myocardial perfusion defect in corresponding segments. GRst = (ECG)-gated rest study; GStr = (ECG)-gated stress study; SA = short axis.

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    TABLE 1

    Baseline Patient Characteristics

    CharacteristicAll patients (n = 90)Patients with TID (n = 30)Patients without TID (n = 60)P
    Age (y)62 ± 1262 ± 1262 ± 120.91
    Male54 (60)18 (60)36 (60)0.99
    BMI30 ± 630 ± 729 ± 70.69
    Diabetes mellitus32 (36)11 (37)21 (35)0.99
    Hypertension87 (96.7)29 (97)58 (97)0.99
    Hyperlipidemia60 (67)22 (73)38 (63)0.48
    Current smoker33 (37)16 (57)17 (27)0.17
    Family history43 (47.8)19 (60)24 (40)0.22
    White55 (61)18 (60)37 (62)0.99
    • Data are n, with percentages in parentheses, or mean ± SD, unless otherwise indicated.

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    TABLE 2

     Patient Physiologic Parameters During SPECT MPI

    CharacteristicAll patients (n = 90)Patients with TID (n = 30)Patients without TID (n = 60)P
    Heart rate (stress)128 ± 31128 ± 28129 ± 320.935
    Systolic blood pressure (stress)161 ± 29158 ± 28162 ± 310.312
    Atrial fibrillation3 (3)2 (7)1 (2)0.613
    • Data are n, with percentages in parentheses, or mean ± SD, unless otherwise indicated.

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Journal of Nuclear Medicine: 55 (6)
Journal of Nuclear Medicine
Vol. 55, Issue 6
June 1, 2014
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Transient Ischemic Dilation of the Left Ventricle on SPECT: Correlation with Findings at Coronary CT Angiography
William T. Halligan, Pamela B. Morris, U. Joseph Schoepf, Blaine T. Mischen, James V. Spearman, J. Reid Spears, Philipp Blanke, Young Jun Cho, Justin R. Silverman, Salvatore A. Chiaramida, Ullrich Ebersberger
Journal of Nuclear Medicine Jun 2014, 55 (6) 917-922; DOI: 10.2967/jnumed.113.125880

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Transient Ischemic Dilation of the Left Ventricle on SPECT: Correlation with Findings at Coronary CT Angiography
William T. Halligan, Pamela B. Morris, U. Joseph Schoepf, Blaine T. Mischen, James V. Spearman, J. Reid Spears, Philipp Blanke, Young Jun Cho, Justin R. Silverman, Salvatore A. Chiaramida, Ullrich Ebersberger
Journal of Nuclear Medicine Jun 2014, 55 (6) 917-922; DOI: 10.2967/jnumed.113.125880
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Keywords

  • myocardial perfusion imaging
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