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Research ArticleClinical Investigations

In Vivo Imaging of Human Cholinergic Nerve Terminals with (–)-5-18F-Fluoroethoxybenzovesamicol: Biodistribution, Dosimetry, and Tracer Kinetic Analyses

Myria Petrou, Kirk A. Frey, Michael R. Kilbourn, Peter J.H. Scott, David M. Raffel, Nicolaas I. Bohnen, Martijn L.T.M. Müller, Roger L. Albin and Robert A. Koeppe
Journal of Nuclear Medicine March 2014, 55 (3) 396-404; DOI: https://doi.org/10.2967/jnumed.113.124792
Myria Petrou
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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Kirk A. Frey
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
2Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan; and
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Michael R. Kilbourn
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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Peter J.H. Scott
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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David M. Raffel
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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Nicolaas I. Bohnen
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
2Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan; and
3Neurology Service and GRECC, VAAAHS, Ann Arbor, Michigan
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Martijn L.T.M. Müller
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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Roger L. Albin
2Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan; and
3Neurology Service and GRECC, VAAAHS, Ann Arbor, Michigan
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Robert A. Koeppe
1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
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Article Information

vol. 55 no. 3 396-404
DOI 
https://doi.org/10.2967/jnumed.113.124792
PubMed 
24481024

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication April 13, 2013
  • Accepted for publication October 10, 2013
  • Published online March 3, 2014.

Article Versions

  • previous version (January 30, 2014 - 05:29).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Myria Petrou1,
  2. Kirk A. Frey1,2,
  3. Michael R. Kilbourn1,
  4. Peter J.H. Scott1,
  5. David M. Raffel1,
  6. Nicolaas I. Bohnen1–3,
  7. Martijn L.T.M. Müller1,
  8. Roger L. Albin2,3 and
  9. Robert A. Koeppe1
  1. 1Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical School, Ann Arbor, Michigan
  2. 2Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan; and
  3. 3Neurology Service and GRECC, VAAAHS, Ann Arbor, Michigan
  1. For correspondence contact: Robert A. Koeppe, University of Michigan, 2276 Med Sci I, SPC 5610, 1301 Catherine, Ann Arbor, MI 48109-5610. E-mail: koeppe{at}umich.edu
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Journal of Nuclear Medicine: 55 (3)
Journal of Nuclear Medicine
Vol. 55, Issue 3
March 1, 2014
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In Vivo Imaging of Human Cholinergic Nerve Terminals with (–)-5-18F-Fluoroethoxybenzovesamicol: Biodistribution, Dosimetry, and Tracer Kinetic Analyses
Myria Petrou, Kirk A. Frey, Michael R. Kilbourn, Peter J.H. Scott, David M. Raffel, Nicolaas I. Bohnen, Martijn L.T.M. Müller, Roger L. Albin, Robert A. Koeppe
Journal of Nuclear Medicine Mar 2014, 55 (3) 396-404; DOI: 10.2967/jnumed.113.124792

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In Vivo Imaging of Human Cholinergic Nerve Terminals with (–)-5-18F-Fluoroethoxybenzovesamicol: Biodistribution, Dosimetry, and Tracer Kinetic Analyses
Myria Petrou, Kirk A. Frey, Michael R. Kilbourn, Peter J.H. Scott, David M. Raffel, Nicolaas I. Bohnen, Martijn L.T.M. Müller, Roger L. Albin, Robert A. Koeppe
Journal of Nuclear Medicine Mar 2014, 55 (3) 396-404; DOI: 10.2967/jnumed.113.124792
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