Research ArticleBasic Science Investigations
N-Terminal Modifications Improve the Receptor Affinity and Pharmacokinetics of Radiolabeled Peptidic Gastrin-Releasing Peptide Receptor Antagonists: Examples of 68Ga- and 64Cu-Labeled Peptides for PET Imaging
Eleni Gourni, Rosalba Mansi, Mazen Jamous, Beatrice Waser, Christiane Smerling, Antje Burian, Franz Buchegger, Jean Claude Reubi and Helmut R. Maecke
Journal of Nuclear Medicine October 2014, 55 (10) 1719-1725; DOI: https://doi.org/10.2967/jnumed.114.141242
Eleni Gourni
1German Cancer Consortium (DKTK), Heidelberg, Germany
2Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany
3German Cancer Research Center (DKFZ), Heidelberg, Germany
Rosalba Mansi
2Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany
4Division of Radiological Chemistry, University Hospital Basel, Basel, Switzerland
Mazen Jamous
4Division of Radiological Chemistry, University Hospital Basel, Basel, Switzerland
Beatrice Waser
5Department of Pathology, University Hospital Bern, Bern, Switzerland
Christiane Smerling
63B Pharmaceuticals, Berlin, Germany; and
Antje Burian
63B Pharmaceuticals, Berlin, Germany; and
Franz Buchegger
7Department of Nuclear Medicine, Lausanne University Hospital, Lausanne, Switzerland
Jean Claude Reubi
5Department of Pathology, University Hospital Bern, Bern, Switzerland
Helmut R. Maecke
2Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany
Data supplements
Supplemental Data
Files in this Data Supplement:
In this issue
Journal of Nuclear Medicine
Vol. 55, Issue 10
October 1, 2014
N-Terminal Modifications Improve the Receptor Affinity and Pharmacokinetics of Radiolabeled Peptidic Gastrin-Releasing Peptide Receptor Antagonists: Examples of 68Ga- and 64Cu-Labeled Peptides for PET Imaging
Eleni Gourni, Rosalba Mansi, Mazen Jamous, Beatrice Waser, Christiane Smerling, Antje Burian, Franz Buchegger, Jean Claude Reubi, Helmut R. Maecke
Journal of Nuclear Medicine Oct 2014, 55 (10) 1719-1725; DOI: 10.2967/jnumed.114.141242
N-Terminal Modifications Improve the Receptor Affinity and Pharmacokinetics of Radiolabeled Peptidic Gastrin-Releasing Peptide Receptor Antagonists: Examples of 68Ga- and 64Cu-Labeled Peptides for PET Imaging
Eleni Gourni, Rosalba Mansi, Mazen Jamous, Beatrice Waser, Christiane Smerling, Antje Burian, Franz Buchegger, Jean Claude Reubi, Helmut R. Maecke
Journal of Nuclear Medicine Oct 2014, 55 (10) 1719-1725; DOI: 10.2967/jnumed.114.141242