Hybrid SLN biopsy guidance: van den Berg and colleagues provide an update and overview of technological innovations that can improve surgical guidance during sentinel lymph node biopsy procedures.
PET, RT, and head and neck cancer: Menda and Buatti look at current evidence supporting the predictive utility of early PET imaging during radiotherapy in patients with head and neck cancer.
Functional PET in uterine tumors: Zhao and colleagues investigate information about sex hormone receptors and indices of tumor proliferation provided by 18F-FES and 18F-FDG PET in patients with mesenchymal uterine tumors.
18F-FDG PET/CT in T/NK cell lymphomas: Li et al. assess the value of interim and posttherapy PET/CT as predictors of progression-free and overall survival in T-cell and natural killer lymphomas.
99mTc-MAA uptake in CRC liver lesions: Ulrich and colleagues research the predictive value of pretherapy intratumoral 99mTc-MAA uptake on perfusion scintigraphy in patients with colorectal liver metastases scheduled for 90Y-microsphere radioembolization.
Brown fat O2 consumption: Muzik and colleagues determine to what extent brown adipose tissue thermogenesis is activated during cold stress in an effort to elucidate relationships between 18F-FDG tracer uptake on PET and brown fat oxidative metabolism.
18F-FLT PET and early therapy response: Hoeben and colleagues study the use of sequential 18F-FLT PET to monitor early response to radiation or chemotherapy for head and neck cancer.
Prognostic impact of mIBG scoring: Yanik and colleagues from the Children’s Oncology Group look at the predictive capabilities of metaiodobenzylguanidine imaging in patients with stage 4 neuroblastoma at various time points in diagnosis and treatment.
Artificial intelligence SPECT: Arsanjani and colleagues report on efforts to improve the diagnostic accuracy of automatic myocardial perfusion SPECT interpretation analysis for prediction of coronary artery disease by integrating quantitative perfusion and functional variables using a computer machine learning method.
CZT MPI SPECT and LV function: Cochet and colleagues evaluate myocardial perfusion imaging using cadmium-zinc-telluride SPECT cameras to measure left ventricular global and regional function and also assess absolute wall motion and thickness measurements with cardiac MR as a reference.
Sex differences in extraaortic 18F-FDG: Kaneko and colleagues describe differences in extraaortic arterial 18F-FDG accumulation in asymptomatic men and women to clarify the association between such accumulation and both cardiovascular risk factors and coronary artery stenosis.
Software reproducibility of 82Rb PET MBF: deKemp and colleagues detail the performance of 3 highly automated software programs commonly used for absolute myocardial blood flow and flow reserve assessment with 82Rb PET imaging.
99mTc(CO)3(NTA) and 131I-OIH: Taylor and colleagues compare the pharmacokinetics of these tracers in imaging patients with stage 3–4 renal failure and describe the potential of the new 99mTc agent for routine clinical measurement of effective renal plasma flow.
PET/CT lymphoscintigraphy in oral cancer: Heuveling and colleagues investigate the clinical feasibility of PET/CT lymphoscintigraphy using 89Zr-nanocolloidal albumin in patients with early-stage oral cancer.
Dynamic bone imaging: Wong and Piert offer an educational overview of the mechanisms of uptake of 99mTc-labeled diphosphonates and 18F-sodium fluoride and discuss and compare the performance of these bone-seeking radiotracers in clinical and research applications.
In vivo Bmax and Kd of 11C-GR103545: Tomasi and colleagues describe the development of this selective κ-opioid receptor PET tracer and the results of a study in rhesus monkeys to estimate in vivo receptor concentration and dissociation equilibrium constant.
PET and cardiac hypertrophy: Zhong and colleagues use a mouse model of transverse aortic constriction to explore the hypothesis that metabolic remodeling with increased 18F-FDG uptake precedes and triggers severe contractile dysfunction in pressure-overload left ventricular hypertrophy.
Imaging V/Q in a model of COPD: Jobse and colleagues assess ventilation/perfusion SPECT imaging in mouse studies to determine the ways in which chronic exposure to cigarette smoke affects the lungs, with special reference to early functional changes.
Hepatobiliary transport and SPECT: Neyt and colleagues demonstrate a noninvasive method to visualize and quantify disturbances in hepatic uptake and biliary efflux of 99mTc-mebrofenin.
4D CT generation from 4D PET: Fayad and colleagues present a method for dynamic CT image generation from a combination of a reference CT image and deformation matrices obtained from elastic registration of 4D PET images not corrected for attenuation.
Optical/nuclear small-animal imaging: Solomon and colleagues report on a fiber-based fluorescence-mediated tomography system combined with a preclinical SPECT/CT platform and results in proof-of-concept studies in rats.
Guidelines for inflammation/infection imaging: Donohoe and other experts from the SNMMI and the European Association of Nuclear Medicine detail new evidence-based guidelines for performing 18F-FDG PET or PET/CT in inflammation and infection.
ON THE COVER
As can be seen in this patient, SPECT/CT clarifies the anatomic location of the SLNs located outside the extended pelvic lymphadenectomy field (white and pink arrows). See page 493.
- © 2013 by the Society of Nuclear Medicine and Molecular Imaging, Inc.
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